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Found 2 Enz. Inhib. hit(s) with Target = 'Cathepsin S' and Monomerid = 50314241
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314241(2-(5-(1-(2-hydroxy-3-(4-(pyridin-2-yl)piperidin-1-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314241(2-(5-(1-(2-hydroxy-3-(4-(pyridin-2-yl)piperidin-1-...)
Affinity DataIC50:  1.54E+3nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of invariant chain p10li after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed