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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Monomerid = 50314598   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50314598
PNG
(CHEMBL1090759 | N-(3-chloro-4-(4-ethylpiperazin-1-...)
Show SMILES CCN1CCN(CC1)c1ccc(NC(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1Cl
Show InChI InChI=1S/C21H20ClF6N3O/c1-2-30-5-7-31(8-6-30)18-4-3-16(12-17(18)22)29-19(32)13-9-14(20(23,24)25)11-15(10-13)21(26,27)28/h3-4,9-12H,2,5-8H2,1H3,(H,29,32)
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UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Antagonist activity at human muscarinic M3 receptor expressed in CHO-K1 cells assessed as inhibition of acetylcholine-induced calcium mobilization


Bioorg Med Chem Lett 20: 2174-7 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.041
BindingDB Entry DOI: 10.7270/Q2D50N38
More data for this
Ligand-Target Pair