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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-Lipoxygenase' and Monomerid = 50315285   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Homo sapiens (human))
BDBM50315285
PNG
(CHEMBL1089840 | aR-6,7-dihydro-6-(10-hydroxyethyl)...)
Show SMILES COc1cc2CC(C)(Cc3cc(OC)c(O)c(O)c3-c2c(O)c1O)C(C)O
Show InChI InChI=1S/C20H24O7/c1-9(21)20(2)7-10-5-12(26-3)16(22)18(24)14(10)15-11(8-20)6-13(27-4)17(23)19(15)25/h5-6,9,21-25H,7-8H2,1-4H3
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Similars

Article
PubMed
n/an/a 4.20E+3n/an/an/an/an/an/a



University of Graz

Curated by ChEMBL


Assay Description
Inhibition of 5-LOX-mediated LTB4 production in stimulated human neutrophile granulocytes after 10 mins by EIA


Bioorg Med Chem 18: 2809-15 (2010)


Article DOI: 10.1016/j.bmc.2009.10.031
BindingDB Entry DOI: 10.7270/Q2MG7PNG
More data for this
Ligand-Target Pair