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Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H4 Receptor' and Monomerid = 50315326   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50315326
PNG
(1-(8-chlorobenzofuro[3,2-d]pyrimidin-4-yl)-N-ethyl...)
Show SMILES CCNC1CCN(C1)c1ncnc2c3cc(Cl)ccc3oc12
Show InChI InChI=1/C16H17ClN4O/c1-2-18-11-5-6-21(8-11)16-15-14(19-9-20-16)12-7-10(17)3-4-13(12)22-15/h3-4,7,9,11,18H,2,5-6,8H2,1H3
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UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Argenta Discovery Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]histamine dihydrochloride from human histamine H4 receptor after 2.5 hrs by scintillation proximity assay


Bioorg Med Chem Lett 20: 2516-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.097
BindingDB Entry DOI: 10.7270/Q2CN74V3
More data for this
Ligand-Target Pair