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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Monomerid = 50316010   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50316010
PNG
(9-Amino-7-cyclopropyl-3-p-tolyl-3H-thieno[2,3-d:4,...)
Show SMILES Cc1ccc(cc1)-n1cnc2c(sc3nc(nc(N)c23)C2CC2)c1=O
Show InChI InChI=1S/C18H15N5OS/c1-9-2-6-11(7-3-9)23-8-20-13-12-15(19)21-16(10-4-5-10)22-17(12)25-14(13)18(23)24/h2-3,6-8,10H,4-5H2,1H3,(H2,19,21,22)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 326n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity at human mGluR1


Bioorg Med Chem Lett 20: 2474-7 (2010)


Article DOI: 10.1016/j.bmcl.2010.03.004
BindingDB Entry DOI: 10.7270/Q2TT4R39
More data for this
Ligand-Target Pair