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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Monomerid = 50316012   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50316012
PNG
(9-Amino-3-(4-methoxy-phenyl)-7-methyl-3H-thieno[2,...)
Show SMILES COc1ccc(cc1)-n1cnc2c(sc3nc(C)nc(N)c23)c1=O
Show InChI InChI=1S/C16H13N5O2S/c1-8-19-14(17)11-12-13(24-15(11)20-8)16(22)21(7-18-12)9-3-5-10(23-2)6-4-9/h3-7H,1-2H3,(H2,17,19,20)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 188n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity at human mGluR1


Bioorg Med Chem Lett 20: 2474-7 (2010)


Article DOI: 10.1016/j.bmcl.2010.03.004
BindingDB Entry DOI: 10.7270/Q2TT4R39
More data for this
Ligand-Target Pair