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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Peroxisome proliferator-activated receptor alpha' and Monomerid = 50317119   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50317119
PNG
(2-((3-((2-(4-chlorophenyl)thiazol-4-yl)methoxy)ben...)
Show SMILES COC(=O)N(CC(O)=O)Cc1cccc(OCc2csc(n2)-c2ccc(Cl)cc2)c1
Show InChI InChI=1S/C21H19ClN2O5S/c1-28-21(27)24(11-19(25)26)10-14-3-2-4-18(9-14)29-12-17-13-30-20(23-17)15-5-7-16(22)8-6-15/h2-9,13H,10-12H2,1H3,(H,25,26)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 90n/an/an/an/a



Bristol-Myers Squibb R&D

Curated by ChEMBL


Assay Description
Agonist activity against human Gal4-fussed PPARalpha in HEK293 cells by luciferase reporter gene assay


Bioorg Med Chem Lett 20: 2933-7 (2010)


Article DOI: 10.1016/j.bmcl.2010.03.019
BindingDB Entry DOI: 10.7270/Q2K35TS2
More data for this
Ligand-Target Pair