BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Monomerid = 50317331   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50317331
PNG
(1-tert-butyl-N-(3-fluoro-4-(2-(1-methyl-1H-imidazo...)
Show SMILES Cn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)c4cnn(c4C(F)(F)F)C(C)(C)C)cc3F)c2s1
Show InChI InChI=1S/C26H22F4N6O2S/c1-25(2,3)36-23(26(28,29)30)15(11-33-36)24(37)34-14-5-6-19(16(27)9-14)38-20-7-8-31-17-10-21(39-22(17)20)18-12-35(4)13-32-18/h5-13H,1-4H3,(H,34,37)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 70n/an/an/an/an/an/a



MethylGene Inc.

Curated by ChEMBL


Assay Description
Inhibition of c-Met


Bioorg Med Chem Lett 20: 2745-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.03.073
BindingDB Entry DOI: 10.7270/Q24T6JJ6
More data for this
Ligand-Target Pair