BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Monomerid = 50317748   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50317748
PNG
(2-(4-(2-aminopyridin-4-yloxy)-3-fluorophenylamino)...)
Show SMILES Nc1cc(Oc2ccc(Nc3ncccc3C(=O)Nc3ccc(Cl)cc3)cc2F)ccn1
Show InChI InChI=1S/C23H17ClFN5O2/c24-14-3-5-15(6-4-14)30-23(31)18-2-1-10-28-22(18)29-16-7-8-20(19(25)12-16)32-17-9-11-27-21(26)13-17/h1-13H,(H2,26,27)(H,28,29)(H,30,31)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 11n/an/an/an/an/an/a



Bristol-Myers Squibb Research and Development

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged human recombinant c-met N terminal domain expressed in Hi5 insect cells after 60 mins by liquid scintillation counting


Bioorg Med Chem Lett 20: 2998-3002 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.042
BindingDB Entry DOI: 10.7270/Q2PN95TM
More data for this
Ligand-Target Pair