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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Monomerid = 50318340   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50318340
PNG
(5-hexyl-3-(3-(methylsulfonyl)phenyl)oxazolidin-2-o...)
Show SMILES CCCCCCC1CN(C(=O)O1)c1cccc(c1)S(C)(=O)=O
Show InChI InChI=1S/C16H23NO4S/c1-3-4-5-6-9-14-12-17(16(18)21-14)13-8-7-10-15(11-13)22(2,19)20/h7-8,10-11,14H,3-6,9,12H2,1-2H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 2.70E+3n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...


Bioorg Med Chem Lett 20: 3129-33 (2010)


Article DOI: 10.1016/j.bmcl.2010.03.089
BindingDB Entry DOI: 10.7270/Q2Z038B7
More data for this
Ligand-Target Pair