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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Monomerid = 50318357   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50318357
PNG
(5-((3-tert-butylphenoxy)methyl)-3-phenyloxazolidin...)
Show SMILES CC(C)(C)c1cccc(OCC2CN(C(=O)O2)c2ccccc2)c1
Show InChI InChI=1S/C20H23NO3/c1-20(2,3)15-8-7-11-17(12-15)23-14-18-13-21(19(22)24-18)16-9-5-4-6-10-16/h4-12,18H,13-14H2,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 350n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...


Bioorg Med Chem Lett 20: 3129-33 (2010)


Article DOI: 10.1016/j.bmcl.2010.03.089
BindingDB Entry DOI: 10.7270/Q2Z038B7
More data for this
Ligand-Target Pair