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Found 1 Enz. Inhib. hit(s) with Target = 'Phosphodiesterase 10A' and Monomerid = 50319182
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Biotie Therapies

Curated by ChEMBL
LigandPNGBDBM50319182(8-Methoxy-3-methyl-1-propyl-4-ureido-imidazo[1,5-a...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human recombinant PDE10A expressed in baculovirus-SF21 cell system assessed as hydrolysis of [3H]cAMP after 1 hr by liquid scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed