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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycine transporter 1' and Monomerid = 50322445   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM50322445
PNG
(CHEMBL1172010 | rac-[5-Methanesulfonyl-2-(2,2,2-tr...)
Show SMILES COc1ccc(cc1)N1CCN(CC1)C(=O)c1cc(ccc1OC(C)C(F)(F)F)S(C)(=O)=O
Show InChI InChI=1S/C22H25F3N2O5S/c1-15(22(23,24)25)32-20-9-8-18(33(3,29)30)14-19(20)21(28)27-12-10-26(11-13-27)16-4-6-17(31-2)7-5-16/h4-9,14-15H,10-13H2,1-3H3
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 430n/an/an/an/a



F. Hoffmann-La Roche Ltd.

Curated by ChEMBL


Assay Description
Inhibition of human GlyT1b expressed in CHO cells assessed as inhibition of [3H]glycine uptake by liquid scintillation counting


J Med Chem 53: 4603-14 (2010)


Article DOI: 10.1021/jm100210p
BindingDB Entry DOI: 10.7270/Q28916TT
More data for this
Ligand-Target Pair