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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cathepsin S' and Monomerid = 50323078   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cathepsin S


(Homo sapiens (Human))
BDBM50323078
PNG
(4-(3-isobutylphenyl)-6-propylpyrimidine-2-carbonit...)
Show SMILES CCCc1cc(nc(n1)C#N)-c1cccc(CC(C)C)c1
Show InChI InChI=1S/C18H21N3/c1-4-6-16-11-17(21-18(12-19)20-16)15-8-5-7-14(10-15)9-13(2)3/h5,7-8,10-11,13H,4,6,9H2,1-3H3
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 224n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human recombinant cathepsin S


Bioorg Med Chem Lett 20: 4447-50 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.049
BindingDB Entry DOI: 10.7270/Q2RJ4JP2
More data for this
Ligand-Target Pair