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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '5-Lipoxygenase' and Monomerid = 50323699   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Homo sapiens (Human))
BDBM50323699
PNG
(2-(benzyloxy)naphthalene | 2-Benzyloxy-naphthalene...)
Show SMILES C(Oc1ccc2ccccc2c1)c1ccccc1
Show InChI InChI=1S/C17H14O/c1-2-6-14(7-3-1)13-18-17-11-10-15-8-4-5-9-16(15)12-17/h1-12H,13H2
PDB
MMDB

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PC sid
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Article
PubMed
n/an/a 7.50E+3n/an/an/an/an/an/a



Max Planck Institute of Molecular Physiology

Curated by ChEMBL


Assay Description
Inhibition of 5-LOX


J Med Chem 55: 5989-6001 (2012)


Article DOI: 10.1021/jm300288g
BindingDB Entry DOI: 10.7270/Q2J38TPJ
More data for this
Ligand-Target Pair
Arachidonate 5-lipoxygenase


(Homo sapiens (Human))
BDBM50323699
PNG
(2-(benzyloxy)naphthalene | 2-Benzyloxy-naphthalene...)
Show SMILES C(Oc1ccc2ccccc2c1)c1ccccc1
Show InChI InChI=1S/C17H14O/c1-2-6-14(7-3-1)13-18-17-11-10-15-8-4-5-9-16(15)12-17/h1-12H,13H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 9.50E+3n/an/an/an/an/an/a



Institut für Molekulare Physiologie

Curated by ChEMBL


Assay Description
Inhibition of LOX5 in human whole blood assessed as inhibition of conversion of aracidonic acid to leukotrine


Nat Chem Biol 5: 585-92 (2009)


Article DOI: 10.1038/nchembio.188
BindingDB Entry DOI: 10.7270/Q2MP53F2
More data for this
Ligand-Target Pair