Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mineralocorticoid receptor' and Monomerid = 50324116   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50324116 ((R)-Methyl 2-((1H-Tetrazol-1-yl)methyl)-4-(2-chlor...) Show SMILES COC(=O)C1=C(Cn2cnnn2)N=C(C)C(C#N)[C@H]1c1ccc(F)cc1Cl Show InChI InChI=1S/C17H14ClFN6O2/c1-9-12(6-20)15(11-4-3-10(19)5-13(11)18)16(17(26)27-2)14(22-9)7-25-8-21-23-24-25/h3-5,8,12,15H,7H2,1-2H3/t12?,15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Antagonist activity at mineralocorticoid receptor LBD expressed in human HUH7 cells coexpressing GAL4 by luciferase reporter gene assay				J Med Chem 53: 5970-8 (2010) Article DOI: 10.1021/jm100506y BindingDB Entry DOI: 10.7270/Q2XW4KST
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