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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Monomerid = 50327690   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50327690
PNG
(3-(2-(Pyridin-2-yl)-4,5,6,7-tetrahydrooxazolo[5,4-...)
Show SMILES O=C(N1CCc2nc(oc2C1)-c1ccccn1)c1cccc(c1)C#N
Show InChI InChI=1S/C19H14N4O2/c20-11-13-4-3-5-14(10-13)19(24)23-9-7-15-17(12-23)25-18(22-15)16-6-1-2-8-21-16/h1-6,8,10H,7,9,12H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 2.60E+3n/an/an/an/an/an/a



Sepracor Inc.

Curated by ChEMBL


Assay Description
Modulation of human recombinant mGluR5 expressed in CHO cells assessed as inhibition of glutamate-induced response


J Med Chem 53: 7107-18 (2010)


Article DOI: 10.1021/jm100736h
BindingDB Entry DOI: 10.7270/Q20G3KCJ
More data for this
Ligand-Target Pair