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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Monomerid = 50327693   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50327693
PNG
(3-(2-(pyridin-2-yl)-3aH-pyrrolo[3,4-d]oxazol-5(4H,...)
Show SMILES N#Cc1cccc(c1)N1CC2OC(=NC2C1)c1ccccn1
Show InChI InChI=1S/C17H14N4O/c18-9-12-4-3-5-13(8-12)21-10-15-16(11-21)22-17(20-15)14-6-1-2-7-19-14/h1-8,15-16H,10-11H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 129n/an/an/an/an/an/a



Sepracor Inc.

Curated by ChEMBL


Assay Description
Modulation of human recombinant mGluR5 expressed in CHO cells assessed as inhibition of glutamate-induced response


J Med Chem 53: 7107-18 (2010)


Article DOI: 10.1021/jm100736h
BindingDB Entry DOI: 10.7270/Q20G3KCJ
More data for this
Ligand-Target Pair