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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Monomerid = 50327695   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50327695
PNG
(3-Fluoro-5-(2-(pyridin-2-yl)-7,8-dihydro-4H-oxazol...)
Show SMILES Fc1cc(cc(c1)N1CCCc2oc(nc2C1)-c1ccccn1)C#N
Show InChI InChI=1S/C19H15FN4O/c20-14-8-13(11-21)9-15(10-14)24-7-3-5-18-17(12-24)23-19(25-18)16-4-1-2-6-22-16/h1-2,4,6,8-10H,3,5,7,12H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 16n/an/an/an/an/an/a



Sepracor Inc.

Curated by ChEMBL


Assay Description
Modulation of human recombinant mGluR5 expressed in CHO cells assessed as inhibition of glutamate-induced response


J Med Chem 53: 7107-18 (2010)


Article DOI: 10.1021/jm100736h
BindingDB Entry DOI: 10.7270/Q20G3KCJ
More data for this
Ligand-Target Pair