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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Beta-1 Adrenergic Receptor' and Monomerid = 50328332   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-1 adrenergic receptor


(Homo sapiens (Human))
BDBM50328332
PNG
(1-(1-(5-phenylthieno[2,3-d]pyrimidin-4-yl)piperidi...)
Show SMILES OC(CNC1CCN(CC1)c1ncnc2scc(-c3ccccc3)c12)COc1cccc(OC(F)(F)F)c1
Show InChI InChI=1/C27H27F3N4O3S/c28-27(29,30)37-22-8-4-7-21(13-22)36-15-20(35)14-31-19-9-11-34(12-10-19)25-24-23(18-5-2-1-3-6-18)16-38-26(24)33-17-32-25/h1-8,13,16-17,19-20,31,35H,9-12,14-15H2
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PC cid
PC sid
UniChem

Similars

Article
PubMed
996n/an/an/an/an/an/an/an/a



4SC AG

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant adrenergic beta-1 receptor expressed in CHO cells assessed as cyclic AMP formation by HTRF assay


Bioorg Med Chem Lett 20: 6108-15 (2010)


Article DOI: 10.1016/j.bmcl.2010.08.039
BindingDB Entry DOI: 10.7270/Q2WM1DNR
More data for this
Ligand-Target Pair