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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Excitatory amino acid transporter 1' and Monomerid = 50328515   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Excitatory amino acid transporter 1


(Homo sapiens (Human))
BDBM50328515
PNG
((E)-Ethyl N-3-Cyano-5-oxo-4,7-diphenyl-5,6,7,8-tet...)
Show SMILES CCO\C=N\C1=C(C#N)C(C2=C(CC(CC2=O)c2ccccc2)O1)c1ccccc1
Show InChI InChI=1/C25H22N2O3/c1-2-29-16-27-25-20(15-26)23(18-11-7-4-8-12-18)24-21(28)13-19(14-22(24)30-25)17-9-5-3-6-10-17/h3-12,16,19,23H,2,13-14H2,1H3/b27-16+
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KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Inhibition of human EAAT1 expressed in HEK293 cells by [3H]D-Asp uptake assay


J Med Chem 53: 7180-91 (2010)


Article DOI: 10.1021/jm1009154
BindingDB Entry DOI: 10.7270/Q2VM4CGX
More data for this
Ligand-Target Pair