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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Excitatory amino acid transporter 1' and Monomerid = 50328521   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Excitatory amino acid transporter 1


(Homo sapiens (Human))
BDBM50328521
PNG
(CHEMBL1259100 | anti-2-Amino-5-oxo-4,7-diphenyl-4,...)
Show SMILES N=C1OC2=C([C@@H](C1C#N)c1ccccc1)C(=O)O[C@@H](C2)c1ccccc1
Show InChI InChI=1/C21H16N2O3/c22-12-15-18(14-9-5-2-6-10-14)19-17(25-20(15)23)11-16(26-21(19)24)13-7-3-1-4-8-13/h1-10,15-16,18,23H,11H2/t15?,16-,18+/s2
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>3.00E+5n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Inhibition of human EAAT1 expressed in HEK293 cells by [3H]D-Asp uptake assay


J Med Chem 53: 7180-91 (2010)


Article DOI: 10.1021/jm1009154
BindingDB Entry DOI: 10.7270/Q2VM4CGX
More data for this
Ligand-Target Pair