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Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Monomerid = 50330811   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50330811
PNG
(2-Chloro-5-[[(5-(o-hydroxyl-p-methoxyphenyl)-1,3,4...)
Show SMILES COc1ccc(-c2nnc(SCc3ccc(Cl)nc3)o2)c(O)c1
Show InChI InChI=1S/C15H12ClN3O3S/c1-21-10-3-4-11(12(20)6-10)14-18-19-15(22-14)23-8-9-2-5-13(16)17-7-9/h2-7,20H,8H2,1H3
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.30E+3n/an/an/an/an/an/a



Nanjing University

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human SGC7901 cells by TRAP assay


Bioorg Med Chem 18: 7836-41 (2010)


Article DOI: 10.1016/j.bmc.2010.09.051
BindingDB Entry DOI: 10.7270/Q2930TDR
More data for this
Ligand-Target Pair