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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Src' and Monomerid = 6079   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM6079
PNG
(7-[(2,4-Dichloro-5-methoxyphenyl)amino]-2-{4-[(4-m...)
Show SMILES COc1cc(Nc2c(cnc3cc(sc23)-c2ccc(cc2)C(=O)N2CCN(C)CC2)C#N)c(Cl)cc1Cl
Show InChI InChI=1S/C27H23Cl2N5O2S/c1-33-7-9-34(10-8-33)27(35)17-5-3-16(4-6-17)24-13-22-26(37-24)25(18(14-30)15-31-22)32-21-12-23(36-2)20(29)11-19(21)28/h3-6,11-13,15H,7-10H2,1-2H3,(H,31,32)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 13n/an/an/an/a7.537



Wyeth Research



Assay Description
Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...


J Med Chem 48: 3891-902 (2005)


Article DOI: 10.1021/jm050175p
BindingDB Entry DOI: 10.7270/Q2T43R88
More data for this
Ligand-Target Pair