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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Src' and Monomerid = 6089   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM6089
PNG
(7-[(2,4-Dichlorophenyl)amino]-2-{5-[(4-methylpiper...)
Show SMILES CN1CCN(Cc2cc(cs2)-c2cc3ncc(C#N)c(Nc4ccc(Cl)cc4Cl)c3s2)CC1
Show InChI InChI=1S/C24H21Cl2N5S2/c1-30-4-6-31(7-5-30)13-18-8-15(14-32-18)22-10-21-24(33-22)23(16(11-27)12-28-21)29-20-3-2-17(25)9-19(20)26/h2-3,8-10,12,14H,4-7,13H2,1H3,(H,28,29)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 67n/an/an/an/an/an/a



Wyeth Research



Assay Description
Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...


J Med Chem 48: 3891-902 (2005)


Article DOI: 10.1021/jm050175p
BindingDB Entry DOI: 10.7270/Q2T43R88
More data for this
Ligand-Target Pair