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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Src' and Monomerid = 6116   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM6116
PNG
(4-[(2,4-dichloro-5-methoxyphenyl)amino]-7-[5-(pipe...)
Show SMILES COc1cc(Nc2c(cnc3cc(ccc23)-c2ccc(CN3CCCCC3)s2)C#N)c(Cl)cc1Cl
Show InChI InChI=1S/C27H24Cl2N4OS/c1-34-25-13-24(21(28)12-22(25)29)32-27-18(14-30)15-31-23-11-17(5-7-20(23)27)26-8-6-19(35-26)16-33-9-3-2-4-10-33/h5-8,11-13,15H,2-4,9-10,16H2,1H3,(H,31,32)
PDB
MMDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.20n/an/an/an/a7.530



Wyeth Research



Assay Description
Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...


Bioorg Med Chem Lett 12: 2011-4 (2002)


Article DOI: 10.1016/s0960-894x(02)00302-5
BindingDB Entry DOI: 10.7270/Q2PC30KC
More data for this
Ligand-Target Pair