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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutaminyl Cyclase' and Monomerid = 7961   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutaminyl Cyclase


(Homo sapiens (Human))
BDBM7961
PNG
(1-(6-phenoxyhexyl)-1H-imidazole | Imidazole N-1 de...)
Show SMILES C(CCCn1ccnc1)CCOc1ccccc1
Show InChI InChI=1S/C15H20N2O/c1(6-11-17-12-10-16-14-17)2-7-13-18-15-8-4-3-5-9-15/h3-5,8-10,12,14H,1-2,6-7,11,13H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
6.20E+3n/an/an/an/an/an/an/an/a



Probiodrug AG



Assay Description
QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...


J Biol Chem 278: 49773-9 (2003)


Article DOI: 10.1074/jbc.M309077200
BindingDB Entry DOI: 10.7270/Q2513WDS
More data for this
Ligand-Target Pair