Compile Data Set for Download or QSAR
maximum 50k data
Found 21 from Institutet
TargetD(2) dopamine receptor(Homo sapiens (Human))
Institutet

Curated by ChEMBL
LigandPNGBDBM50007522(5-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,3-dime...)
Affinity DataKi:  0.00300nMAssay Description:Binding affinity to dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institutet

Curated by ChEMBL
LigandPNGBDBM50007522(5-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,3-dime...)
Affinity DataKi:  0.220nMAssay Description:Binding affinity to dopamine D3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Institutet

Curated by ChEMBL
LigandPNGBDBM35229(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...)
Affinity DataKi:  1nMAssay Description:Binding affinity at NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Institutet

Curated by ChEMBL
LigandPNGBDBM50199005((S)-2-((S)-(2-methoxyphenoxy)(phenyl)methyl)morpho...)
Affinity DataKi:  7.93nMAssay Description:Binding affinity at NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Institutet

Curated by ChEMBL
LigandPNGBDBM50199003((R)-1-(10,11-dihydro-dibenzo[b,f]azepin-5-yl)-3-me...)
Affinity DataKi:  8.29nMAssay Description:Binding affinity at NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Institutet

Curated by ChEMBL
LigandPNGBDBM50199004((S,S)-1-cyclopentyl-2-(5-fluoro-2-methoxy-phenyl)-...)
Affinity DataKi:  10.8nMAssay Description:Binding affinity at NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Institutet

Curated by ChEMBL
LigandPNGBDBM50296783((E)-N-(3-iodoprop-2-enyl)-2beta-carbofluoroethoxy-...)
Affinity DataKi:  12nMAssay Description:Displacement of [125I]PE2I from rat DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Institutet

Curated by ChEMBL
LigandPNGBDBM50296782((1R,2S,3S,5S)-methyl 8-((E)-3-iodoallyl)-3-p-tolyl...)
Affinity DataKi:  16nMAssay Description:Displacement of [125I]PE2I from rat DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Institutet

Curated by ChEMBL
LigandPNGBDBM27533(4-(3-(1,4-diazepane-1-carbonyl)-4-fluorobenzyl)pht...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Institutet

Curated by ChEMBL
LigandPNGBDBM27497(2-(dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridi...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Institutet

Curated by ChEMBL
LigandPNGBDBM50277614(2-methyl-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]py...)
Affinity DataKd:  200nMAssay Description:Binding affinity to human PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Institutet

Curated by ChEMBL
LigandPNGBDBM27533(4-(3-(1,4-diazepane-1-carbonyl)-4-fluorobenzyl)pht...)
Affinity DataKd:  19nMAssay Description:Binding affinity to human PARP1 by isothermal titration colorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Institutet

Curated by ChEMBL
LigandPNGBDBM27497(2-(dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridi...)
Affinity DataKd:  110nMAssay Description:Binding affinity to human PARP1 by isothermal titration colorimetryMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Institutet

Curated by ChEMBL
LigandPNGBDBM50277614(2-methyl-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]py...)
Affinity DataKd:  150nMAssay Description:Binding affinity to human PARP1 by isothermal titration colorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Homo sapiens (Human))
Institutet

Curated by ChEMBL
LigandPNGBDBM27533(4-(3-(1,4-diazepane-1-carbonyl)-4-fluorobenzyl)pht...)
Affinity DataKd:  70nMAssay Description:Binding affinity to human PARP3 PARP domain by isothermal titration colorimetryMore data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Homo sapiens (Human))
Institutet

Curated by ChEMBL
LigandPNGBDBM27497(2-(dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridi...)
Affinity DataKd:  700nMAssay Description:Binding affinity to human PARP3 PARP domain by isothermal titration colorimetryMore data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Homo sapiens (Human))
Institutet

Curated by ChEMBL
LigandPNGBDBM50277614(2-methyl-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]py...)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to human PARP3 PARP domain by isothermal titration colorimetryMore data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Homo sapiens (Human))
Institutet

Curated by ChEMBL
LigandPNGBDBM50226518(3-Aminobenzoesaeure | 3-aminobenzoic acid | CHEMBL...)
Affinity DataKd: >2.00E+3nMAssay Description:Binding affinity to human PARP3 PARP domain by isothermal titration colorimetryMore data for this Ligand-Target Pair
TargetCystathionine beta-synthase(Homo sapiens (Human))
Institutet

Curated by ChEMBL
LigandPNGBDBM50550146(CHEMBL4757665)
Affinity DataKd:  9.40E+4nMAssay Description:Binding affinity to human CBS by PLP fluorescence-based screening assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Institutet

Curated by ChEMBL
LigandPNGBDBM50063266(6-Nitro-2-piperazin-1-yl-quinoline | 6-nitroquipaz...)
Affinity DataKd:  0.0510nMAssay Description:Binding affinity of the radio labeled [3H]-5-Methyl-6-nitroquipazine compound against Serotonin transporter in rat frontal cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Institutet

Curated by ChEMBL
LigandPNGBDBM50121451(5-Methyl-6-nitro-2-piperazin-1-yl-quinoline | CHEM...)
Affinity DataKd:  0.0510nMAssay Description:Binding affinity of the radio labeled [3H]-5-Methyl-6-nitroquipazine compound against Serotonin transporter in rat frontal cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed