BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 93 hits with Last Name = 'brown' and Initial = 'br'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50403291
PNG
(CHEMBL69836)
Show SMILES OC(=O)CN1C[C@H](SC[C@H](NC(=O)[C@@H](CS)Cc2ccccc2)C1=O)c1ccccc1
Show InChI InChI=1S/C23H26N2O4S2/c26-21(27)13-25-12-20(17-9-5-2-6-10-17)31-15-19(23(25)29)24-22(28)18(14-30)11-16-7-3-1-4-8-16/h1-10,18-20,30H,11-15H2,(H,24,28)(H,26,27)/t18-,19+,20+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 0.900n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of Neutral Endopeptidase isolated from rat kidney.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50403250
PNG
(CHEMBL51780)
Show SMILES OC(=O)CN1c2ccccc2SC[C@H](NC(=O)[C@@H](CS)Cc2ccccc2)C1=O
Show InChI InChI=1S/C21H22N2O4S2/c24-19(25)11-23-17-8-4-5-9-18(17)29-13-16(21(23)27)22-20(26)15(12-28)10-14-6-2-1-3-7-14/h1-9,15-16,28H,10-13H2,(H,22,26)(H,24,25)/t15-,16+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 1n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of Neutral Endopeptidase isolated from rat kidney.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50403294
PNG
(CHEMBL305020)
Show SMILES OC(=O)CN1CCSC[C@H](NC(=O)[C@@H](CS)Cc2ccccc2)C1=O
Show InChI InChI=1S/C17H22N2O4S2/c20-15(21)9-19-6-7-25-11-14(17(19)23)18-16(22)13(10-24)8-12-4-2-1-3-5-12/h1-5,13-14,24H,6-11H2,(H,18,22)(H,20,21)/t13-,14+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 2.40n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of Neutral Endopeptidase isolated from rat kidney.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50403299
PNG
(CHEMBL305050)
Show SMILES OC(=O)CN1[C@H](SC[C@H](NC(=O)[C@@H](CS)Cc2ccccc2)C1=O)c1ccccc1
Show InChI InChI=1S/C22H24N2O4S2/c25-19(26)12-24-21(28)18(14-30-22(24)16-9-5-2-6-10-16)23-20(27)17(13-29)11-15-7-3-1-4-8-15/h1-10,17-18,22,29H,11-14H2,(H,23,27)(H,25,26)/t17-,18+,22-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 2.5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of Neutral Endopeptidase isolated from rat kidney.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50403298
PNG
(CHEMBL71769)
Show SMILES OC(=O)CN1[C@@H](SC[C@H](NC(=O)[C@@H](CS)Cc2ccccc2)C1=O)c1ccccc1
Show InChI InChI=1S/C22H24N2O4S2/c25-19(26)12-24-21(28)18(14-30-22(24)16-9-5-2-6-10-16)23-20(27)17(13-29)11-15-7-3-1-4-8-15/h1-10,17-18,22,29H,11-14H2,(H,23,27)(H,25,26)/t17-,18+,22+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 2.70n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of Neutral Endopeptidase isolated from rat kidney.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Rattus norvegicus)
BDBM50403301
PNG
(CHEMBL71496)
Show SMILES C[C@@H]1SCC[C@H](NC(=O)[C@@H](S)Cc2ccccc2)C(=O)N1CC(O)=O
Show InChI InChI=1S/C17H22N2O4S2/c1-11-19(10-15(20)21)17(23)13(7-8-25-11)18-16(22)14(24)9-12-5-3-2-4-6-12/h2-6,11,13-14,24H,7-10H2,1H3,(H,18,22)(H,20,21)/t11-,13-,14-/m0/s1
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 11.7n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of angiotensin converting enzyme isolated from rat lung.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Rattus norvegicus)
BDBM50403259
PNG
(CHEMBL298388)
Show SMILES OC(=O)CN1c2ccccc2SC[C@H](NC(=O)[C@@H](S)Cc2ccccc2)C1=O
Show InChI InChI=1S/C20H20N2O4S2/c23-18(24)11-22-15-8-4-5-9-17(15)28-12-14(20(22)26)21-19(25)16(27)10-13-6-2-1-3-7-13/h1-9,14,16,27H,10-12H2,(H,21,25)(H,23,24)/t14-,16-/m0/s1
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 13n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of angiotensin converting enzyme isolated from rat lung.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Rattus norvegicus)
BDBM50403305
PNG
(CHEMBL71351)
Show SMILES CC1(C)CSC[C@H](NC(=O)[C@@H](S)Cc2ccccc2)C(=O)N1CC(O)=O
Show InChI InChI=1S/C18H24N2O4S2/c1-18(2)11-26-10-13(17(24)20(18)9-15(21)22)19-16(23)14(25)8-12-6-4-3-5-7-12/h3-7,13-14,25H,8-11H2,1-2H3,(H,19,23)(H,21,22)/t13-,14-/m0/s1
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 13.8n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of angiotensin converting enzyme isolated from rat lung.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Rattus norvegicus)
BDBM50403250
PNG
(CHEMBL51780)
Show SMILES OC(=O)CN1c2ccccc2SC[C@H](NC(=O)[C@@H](CS)Cc2ccccc2)C1=O
Show InChI InChI=1S/C21H22N2O4S2/c24-19(25)11-23-17-8-4-5-9-18(17)29-13-16(21(23)27)22-20(26)15(12-28)10-14-6-2-1-3-7-14/h1-9,15-16,28H,10-13H2,(H,22,26)(H,24,25)/t15-,16+/m1/s1
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 17n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of angiotensin converting enzyme isolated from rat lung.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Rattus norvegicus)
BDBM50403295
PNG
(CHEMBL67924)
Show SMILES OC(=O)CN1[C@H](SC[C@@H](NC(=O)[C@@H](S)Cc2ccccc2)C1=O)c1ccccc1
Show InChI InChI=1S/C21H22N2O4S2/c24-18(25)12-23-20(27)16(13-29-21(23)15-9-5-2-6-10-15)22-19(26)17(28)11-14-7-3-1-4-8-14/h1-10,16-17,21,28H,11-13H2,(H,22,26)(H,24,25)/t16-,17+,21-/m1/s1
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 20n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of angiotensin converting enzyme isolated from rat lung.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Rattus norvegicus)
BDBM50403293
PNG
(CHEMBL304148)
Show SMILES OC(=O)CN1[C@@H](CSC[C@H](NC(=O)[C@@H](CS)Cc2ccccc2)C1=O)c1ccccc1
Show InChI InChI=1S/C23H26N2O4S2/c26-21(27)12-25-20(17-9-5-2-6-10-17)15-31-14-19(23(25)29)24-22(28)18(13-30)11-16-7-3-1-4-8-16/h1-10,18-20,30H,11-15H2,(H,24,28)(H,26,27)/t18-,19+,20+/m1/s1
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 22n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of angiotensin converting enzyme isolated from rat lung.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Rattus norvegicus)
BDBM50403292
PNG
(CHEMBL71538)
Show SMILES OC(=O)CN1[C@H](SC[C@H](NC(=O)[C@@H](S)Cc2ccccc2)C1=O)c1ccccc1
Show InChI InChI=1S/C21H22N2O4S2/c24-18(25)12-23-20(27)16(13-29-21(23)15-9-5-2-6-10-15)22-19(26)17(28)11-14-7-3-1-4-8-14/h1-10,16-17,21,28H,11-13H2,(H,22,26)(H,24,25)/t16-,17-,21+/m0/s1
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 25n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of angiotensin converting enzyme isolated from rat lung.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Rattus norvegicus)
BDBM50403304
PNG
(CHEMBL420192)
Show SMILES OC(=O)CN1[C@@H](CSC[C@H](NC(=O)[C@@H](S)Cc2ccccc2)C1=O)c1ccccc1
Show InChI InChI=1S/C22H24N2O4S2/c25-20(26)12-24-18(16-9-5-2-6-10-16)14-30-13-17(22(24)28)23-21(27)19(29)11-15-7-3-1-4-8-15/h1-10,17-19,29H,11-14H2,(H,23,27)(H,25,26)/t17-,18-,19-/m0/s1
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 29n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of angiotensin converting enzyme isolated from rat lung.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Rattus norvegicus)
BDBM50403291
PNG
(CHEMBL69836)
Show SMILES OC(=O)CN1C[C@H](SC[C@H](NC(=O)[C@@H](CS)Cc2ccccc2)C1=O)c1ccccc1
Show InChI InChI=1S/C23H26N2O4S2/c26-21(27)13-25-12-20(17-9-5-2-6-10-17)31-15-19(23(25)29)24-22(28)18(14-30)11-16-7-3-1-4-8-16/h1-10,18-20,30H,11-15H2,(H,24,28)(H,26,27)/t18-,19+,20+/m1/s1
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 33n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of angiotensin converting enzyme isolated from rat lung.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50403293
PNG
(CHEMBL304148)
Show SMILES OC(=O)CN1[C@@H](CSC[C@H](NC(=O)[C@@H](CS)Cc2ccccc2)C1=O)c1ccccc1
Show InChI InChI=1S/C23H26N2O4S2/c26-21(27)12-25-20(17-9-5-2-6-10-17)15-31-14-19(23(25)29)24-22(28)18(13-30)11-16-7-3-1-4-8-16/h1-10,18-20,30H,11-15H2,(H,24,28)(H,26,27)/t18-,19+,20+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 40n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of Neutral Endopeptidase isolated from rat kidney.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Rattus norvegicus)
BDBM50403300
PNG
(CHEMBL68849)
Show SMILES OC(=O)CN1C[C@H](SC[C@H](NC(=O)[C@@H](S)Cc2ccccc2)C1=O)c1ccccc1
Show InChI InChI=1S/C22H24N2O4S2/c25-20(26)13-24-12-19(16-9-5-2-6-10-16)30-14-17(22(24)28)23-21(27)18(29)11-15-7-3-1-4-8-15/h1-10,17-19,29H,11-14H2,(H,23,27)(H,25,26)/t17-,18-,19-/m0/s1
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 40n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of angiotensin converting enzyme isolated from rat lung.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Rattus norvegicus)
BDBM50403296
PNG
(CHEMBL67804)
Show SMILES OC(=O)CN1CSCC[C@H](NC(=O)[C@@H](S)Cc2ccccc2)C1=O
Show InChI InChI=1S/C16H20N2O4S2/c19-14(20)9-18-10-24-7-6-12(16(18)22)17-15(21)13(23)8-11-4-2-1-3-5-11/h1-5,12-13,23H,6-10H2,(H,17,21)(H,19,20)/t12-,13-/m0/s1
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 61n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of angiotensin converting enzyme isolated from rat lung.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50403259
PNG
(CHEMBL298388)
Show SMILES OC(=O)CN1c2ccccc2SC[C@H](NC(=O)[C@@H](S)Cc2ccccc2)C1=O
Show InChI InChI=1S/C20H20N2O4S2/c23-18(24)11-22-15-8-4-5-9-17(15)28-12-14(20(22)26)21-19(25)16(27)10-13-6-2-1-3-7-13/h1-9,14,16,27H,10-12H2,(H,21,25)(H,23,24)/t14-,16-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 64n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of Neutral Endopeptidase isolated from rat kidney.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Rattus norvegicus)
BDBM50403306
PNG
(CHEMBL306461)
Show SMILES OC(=O)CN1CCSC[C@H](NC(=O)[C@@H](S)Cc2ccccc2)C1=O
Show InChI InChI=1S/C16H20N2O4S2/c19-14(20)9-18-6-7-24-10-12(16(18)22)17-15(21)13(23)8-11-4-2-1-3-5-11/h1-5,12-13,23H,6-10H2,(H,17,21)(H,19,20)/t12-,13-/m0/s1
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 67n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of angiotensin converting enzyme isolated from rat lung.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Rattus norvegicus)
BDBM50403302
PNG
(CHEMBL71746)
Show SMILES OC(=O)CN1[C@@H](SC[C@H](NC(=O)[C@@H](S)Cc2ccccc2)C1=O)c1ccccc1
Show InChI InChI=1S/C21H22N2O4S2/c24-18(25)12-23-20(27)16(13-29-21(23)15-9-5-2-6-10-15)22-19(26)17(28)11-14-7-3-1-4-8-14/h1-10,16-17,21,28H,11-13H2,(H,22,26)(H,24,25)/t16-,17-,21-/m0/s1
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 73n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of angiotensin converting enzyme isolated from rat lung.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50403300
PNG
(CHEMBL68849)
Show SMILES OC(=O)CN1C[C@H](SC[C@H](NC(=O)[C@@H](S)Cc2ccccc2)C1=O)c1ccccc1
Show InChI InChI=1S/C22H24N2O4S2/c25-20(26)13-24-12-19(16-9-5-2-6-10-16)30-14-17(22(24)28)23-21(27)18(29)11-15-7-3-1-4-8-15/h1-10,17-19,29H,11-14H2,(H,23,27)(H,25,26)/t17-,18-,19-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 99n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of Neutral Endopeptidase isolated from rat kidney.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Rattus norvegicus)
BDBM50403294
PNG
(CHEMBL305020)
Show SMILES OC(=O)CN1CCSC[C@H](NC(=O)[C@@H](CS)Cc2ccccc2)C1=O
Show InChI InChI=1S/C17H22N2O4S2/c20-15(21)9-19-6-7-25-11-14(17(19)23)18-16(22)13(10-24)8-12-4-2-1-3-5-12/h1-5,13-14,24H,6-11H2,(H,18,22)(H,20,21)/t13-,14+/m1/s1
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 100n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of angiotensin converting enzyme isolated from rat lung.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Rattus norvegicus)
BDBM50403298
PNG
(CHEMBL71769)
Show SMILES OC(=O)CN1[C@@H](SC[C@H](NC(=O)[C@@H](CS)Cc2ccccc2)C1=O)c1ccccc1
Show InChI InChI=1S/C22H24N2O4S2/c25-19(26)12-24-21(28)18(14-30-22(24)16-9-5-2-6-10-16)23-20(27)17(13-29)11-15-7-3-1-4-8-15/h1-10,17-18,22,29H,11-14H2,(H,23,27)(H,25,26)/t17-,18+,22+/m1/s1
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 115n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of angiotensin converting enzyme isolated from rat lung.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Rattus norvegicus)
BDBM50403303
PNG
(CHEMBL71711)
Show SMILES OC(=O)CN1[C@H](SC[C@@H](NC(=O)[C@@H](CS)Cc2ccccc2)C1=O)c1ccccc1
Show InChI InChI=1S/C22H24N2O4S2/c25-19(26)12-24-21(28)18(14-30-22(24)16-9-5-2-6-10-16)23-20(27)17(13-29)11-15-7-3-1-4-8-15/h1-10,17-18,22,29H,11-14H2,(H,23,27)(H,25,26)/t17-,18-,22-/m1/s1
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 123n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of angiotensin converting enzyme isolated from rat lung.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50403303
PNG
(CHEMBL71711)
Show SMILES OC(=O)CN1[C@H](SC[C@@H](NC(=O)[C@@H](CS)Cc2ccccc2)C1=O)c1ccccc1
Show InChI InChI=1S/C22H24N2O4S2/c25-19(26)12-24-21(28)18(14-30-22(24)16-9-5-2-6-10-16)23-20(27)17(13-29)11-15-7-3-1-4-8-15/h1-10,17-18,22,29H,11-14H2,(H,23,27)(H,25,26)/t17-,18-,22-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 126n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of Neutral Endopeptidase isolated from rat kidney.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Rattus norvegicus)
BDBM50403299
PNG
(CHEMBL305050)
Show SMILES OC(=O)CN1[C@H](SC[C@H](NC(=O)[C@@H](CS)Cc2ccccc2)C1=O)c1ccccc1
Show InChI InChI=1S/C22H24N2O4S2/c25-19(26)12-24-21(28)18(14-30-22(24)16-9-5-2-6-10-16)23-20(27)17(13-29)11-15-7-3-1-4-8-15/h1-10,17-18,22,29H,11-14H2,(H,23,27)(H,25,26)/t17-,18+,22-/m1/s1
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 167n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of angiotensin converting enzyme isolated from rat lung.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50403306
PNG
(CHEMBL306461)
Show SMILES OC(=O)CN1CCSC[C@H](NC(=O)[C@@H](S)Cc2ccccc2)C1=O
Show InChI InChI=1S/C16H20N2O4S2/c19-14(20)9-18-6-7-24-10-12(16(18)22)17-15(21)13(23)8-11-4-2-1-3-5-11/h1-5,12-13,23H,6-10H2,(H,17,21)(H,19,20)/t12-,13-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 244n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of Neutral Endopeptidase isolated from rat kidney.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50403301
PNG
(CHEMBL71496)
Show SMILES C[C@@H]1SCC[C@H](NC(=O)[C@@H](S)Cc2ccccc2)C(=O)N1CC(O)=O
Show InChI InChI=1S/C17H22N2O4S2/c1-11-19(10-15(20)21)17(23)13(7-8-25-11)18-16(22)14(24)9-12-5-3-2-4-6-12/h2-6,11,13-14,24H,7-10H2,1H3,(H,18,22)(H,20,21)/t11-,13-,14-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 251n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of Neutral Endopeptidase isolated from rat kidney.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Rattus norvegicus)
BDBM50403297
PNG
(CHEMBL306938)
Show SMILES OC(=O)CN1C[C@@H](SC[C@H](NC(=O)[C@@H](S)Cc2ccccc2)C1=O)c1ccccc1
Show InChI InChI=1S/C22H24N2O4S2/c25-20(26)13-24-12-19(16-9-5-2-6-10-16)30-14-17(22(24)28)23-21(27)18(29)11-15-7-3-1-4-8-15/h1-10,17-19,29H,11-14H2,(H,23,27)(H,25,26)/t17-,18-,19+/m0/s1
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 290n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of angiotensin converting enzyme isolated from rat lung.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50403302
PNG
(CHEMBL71746)
Show SMILES OC(=O)CN1[C@@H](SC[C@H](NC(=O)[C@@H](S)Cc2ccccc2)C1=O)c1ccccc1
Show InChI InChI=1S/C21H22N2O4S2/c24-18(25)12-23-20(27)16(13-29-21(23)15-9-5-2-6-10-15)22-19(26)17(28)11-14-7-3-1-4-8-14/h1-10,16-17,21,28H,11-13H2,(H,22,26)(H,24,25)/t16-,17-,21-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 380n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of Neutral Endopeptidase isolated from rat kidney.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50403290
PNG
(CHEMBL302112)
Show SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)N[C@@H](CCCNc1ccccn1)C(=O)N1CCC(C)CC1
Show InChI InChI=1S/C27H34N4O4S/c1-20-12-16-31(17-13-20)27(32)25(6-5-15-29-26-7-3-4-14-28-26)30-36(33,34)24-11-9-21-8-10-23(35-2)18-22(21)19-24/h3-4,7-11,14,18-20,25,30H,5-6,12-13,15-17H2,1-2H3,(H,28,29)/t25-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 470n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against thrombin was measured by its ability to cleave the synthetic substrate S-2238(D-Phe-Pip-Arg-pNA)


Bioorg Med Chem Lett 4: 2165-2170 (1994)


Article DOI: 10.1016/S0960-894X(00)80064-5
BindingDB Entry DOI: 10.7270/Q2JW8G1T
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50403296
PNG
(CHEMBL67804)
Show SMILES OC(=O)CN1CSCC[C@H](NC(=O)[C@@H](S)Cc2ccccc2)C1=O
Show InChI InChI=1S/C16H20N2O4S2/c19-14(20)9-18-10-24-7-6-12(16(18)22)17-15(21)13(23)8-11-4-2-1-3-5-11/h1-5,12-13,23H,6-10H2,(H,17,21)(H,19,20)/t12-,13-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 535n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of Neutral Endopeptidase isolated from rat kidney.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50403292
PNG
(CHEMBL71538)
Show SMILES OC(=O)CN1[C@H](SC[C@H](NC(=O)[C@@H](S)Cc2ccccc2)C1=O)c1ccccc1
Show InChI InChI=1S/C21H22N2O4S2/c24-18(25)12-23-20(27)16(13-29-21(23)15-9-5-2-6-10-15)22-19(26)17(28)11-14-7-3-1-4-8-14/h1-10,16-17,21,28H,11-13H2,(H,22,26)(H,24,25)/t16-,17-,21+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 1.35E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of Neutral Endopeptidase isolated from rat kidney.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50403305
PNG
(CHEMBL71351)
Show SMILES CC1(C)CSC[C@H](NC(=O)[C@@H](S)Cc2ccccc2)C(=O)N1CC(O)=O
Show InChI InChI=1S/C18H24N2O4S2/c1-18(2)11-26-10-13(17(24)20(18)9-15(21)22)19-16(23)14(25)8-12-6-4-3-5-7-12/h3-7,13-14,25H,8-11H2,1-2H3,(H,19,23)(H,21,22)/t13-,14-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 1.56E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of Neutral Endopeptidase isolated from rat kidney.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50403304
PNG
(CHEMBL420192)
Show SMILES OC(=O)CN1[C@@H](CSC[C@H](NC(=O)[C@@H](S)Cc2ccccc2)C1=O)c1ccccc1
Show InChI InChI=1S/C22H24N2O4S2/c25-20(26)12-24-18(16-9-5-2-6-10-16)14-30-13-17(22(24)28)23-21(27)19(29)11-15-7-3-1-4-8-15/h1-10,17-19,29H,11-14H2,(H,23,27)(H,25,26)/t17-,18-,19-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 2.02E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of Neutral Endopeptidase isolated from rat kidney.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50403297
PNG
(CHEMBL306938)
Show SMILES OC(=O)CN1C[C@@H](SC[C@H](NC(=O)[C@@H](S)Cc2ccccc2)C1=O)c1ccccc1
Show InChI InChI=1S/C22H24N2O4S2/c25-20(26)13-24-12-19(16-9-5-2-6-10-16)30-14-17(22(24)28)23-21(27)18(29)11-15-7-3-1-4-8-15/h1-10,17-19,29H,11-14H2,(H,23,27)(H,25,26)/t17-,18-,19+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 2.04E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of Neutral Endopeptidase isolated from rat kidney.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50403287
PNG
(CHEMBL69990)
Show SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)N[C@@H](CCCNc1cccnn1)C(=O)N1CCC(C)CC1
Show InChI InChI=1S/C26H33N5O4S/c1-19-11-15-31(16-12-19)26(32)24(5-3-13-27-25-6-4-14-28-29-25)30-36(33,34)23-10-8-20-7-9-22(35-2)17-21(20)18-23/h4,6-10,14,17-19,24,30H,3,5,11-13,15-16H2,1-2H3,(H,27,29)/t24-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 2.30E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against thrombin was measured by its ability to cleave the synthetic substrate S-2238(D-Phe-Pip-Arg-pNA)


Bioorg Med Chem Lett 4: 2165-2170 (1994)


Article DOI: 10.1016/S0960-894X(00)80064-5
BindingDB Entry DOI: 10.7270/Q2JW8G1T
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50403285
PNG
(CHEMBL66348)
Show SMILES CC1CCN(CC1)C(=O)[C@H](CCCNC(N)=N)NS(=O)(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C22H31N5O3S/c1-16-10-13-27(14-11-16)21(28)20(7-4-12-25-22(23)24)26-31(29,30)19-9-8-17-5-2-3-6-18(17)15-19/h2-3,5-6,8-9,15-16,20,26H,4,7,10-14H2,1H3,(H4,23,24,25)/t20-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 2.50E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against thrombin was measured by its ability to cleave the synthetic substrate S-2238(D-Phe-Pip-Arg-pNA)


Bioorg Med Chem Lett 4: 2165-2170 (1994)


Article DOI: 10.1016/S0960-894X(00)80064-5
BindingDB Entry DOI: 10.7270/Q2JW8G1T
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50403295
PNG
(CHEMBL67924)
Show SMILES OC(=O)CN1[C@H](SC[C@@H](NC(=O)[C@@H](S)Cc2ccccc2)C1=O)c1ccccc1
Show InChI InChI=1S/C21H22N2O4S2/c24-18(25)12-23-20(27)16(13-29-21(23)15-9-5-2-6-10-15)22-19(26)17(28)11-14-7-3-1-4-8-14/h1-10,16-17,21,28H,11-13H2,(H,22,26)(H,24,25)/t16-,17+,21-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 3.82E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of Neutral Endopeptidase isolated from rat kidney.


Bioorg Med Chem Lett 4: 2193-2198 (1994)


Article DOI: 10.1016/S0960-894X(00)80070-0
BindingDB Entry DOI: 10.7270/Q2F47Q9D
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50403288
PNG
(CHEMBL262244)
Show SMILES CC1CCN(CC1)C(=O)[C@H](CCCNc1ccccn1)NS(=O)(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C26H32N4O3S/c1-20-13-17-30(18-14-20)26(31)24(9-6-16-28-25-10-4-5-15-27-25)29-34(32,33)23-12-11-21-7-2-3-8-22(21)19-23/h2-5,7-8,10-12,15,19-20,24,29H,6,9,13-14,16-18H2,1H3,(H,27,28)/t24-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 5.50E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against thrombin was measured by its ability to cleave the synthetic substrate S-2238(D-Phe-Pip-Arg-pNA)


Bioorg Med Chem Lett 4: 2165-2170 (1994)


Article DOI: 10.1016/S0960-894X(00)80064-5
BindingDB Entry DOI: 10.7270/Q2JW8G1T
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50403284
PNG
(CHEMBL66887)
Show SMILES CC1CCN(CC1)C(=O)[C@H](CCCNc1cccnn1)NS(=O)(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C25H31N5O3S/c1-19-12-16-30(17-13-19)25(31)23(8-4-14-26-24-9-5-15-27-28-24)29-34(32,33)22-11-10-20-6-2-3-7-21(20)18-22/h2-3,5-7,9-11,15,18-19,23,29H,4,8,12-14,16-17H2,1H3,(H,26,28)/t23-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 2.40E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against thrombin was measured by its ability to cleave the synthetic substrate S-2238(D-Phe-Pip-Arg-pNA)


Bioorg Med Chem Lett 4: 2165-2170 (1994)


Article DOI: 10.1016/S0960-894X(00)80064-5
BindingDB Entry DOI: 10.7270/Q2JW8G1T
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50403286
PNG
(CHEMBL304592)
Show SMILES CC1CCN(CC1)C(=O)[C@H](CCCNc1cnccn1)NS(=O)(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C25H31N5O3S/c1-19-10-15-30(16-11-19)25(31)23(7-4-12-27-24-18-26-13-14-28-24)29-34(32,33)22-9-8-20-5-2-3-6-21(20)17-22/h2-3,5-6,8-9,13-14,17-19,23,29H,4,7,10-12,15-16H2,1H3,(H,27,28)/t23-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a>4.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against thrombin was measured by its ability to cleave the synthetic substrate S-2238(D-Phe-Pip-Arg-pNA)


Bioorg Med Chem Lett 4: 2165-2170 (1994)


Article DOI: 10.1016/S0960-894X(00)80064-5
BindingDB Entry DOI: 10.7270/Q2JW8G1T
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50403289
PNG
(CHEMBL68474)
Show SMILES CC1CCN(CC1)C(=O)[C@H](CCCNc1ncccn1)NS(=O)(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C25H31N5O3S/c1-19-11-16-30(17-12-19)24(31)23(8-4-13-26-25-27-14-5-15-28-25)29-34(32,33)22-10-9-20-6-2-3-7-21(20)18-22/h2-3,5-7,9-10,14-15,18-19,23,29H,4,8,11-13,16-17H2,1H3,(H,26,27,28)/t23-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a>1.15E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against thrombin was measured by its ability to cleave the synthetic substrate S-2238(D-Phe-Pip-Arg-pNA)


Bioorg Med Chem Lett 4: 2165-2170 (1994)


Article DOI: 10.1016/S0960-894X(00)80064-5
BindingDB Entry DOI: 10.7270/Q2JW8G1T
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50010072
PNG
(CHEMBL318673 | [3-(5-oxabicyclo[2.2.1],3-formaldeh...)
Show SMILES OC(=O)COc1cccc(CC2C3CCC(O3)C2C=NNC(=O)Nc2ccccc2)c1
Show InChI InChI=1S/C23H25N3O5/c27-22(28)14-30-17-8-4-5-15(11-17)12-18-19(21-10-9-20(18)31-21)13-24-26-23(29)25-16-6-2-1-3-7-16/h1-8,11,13,18-21H,9-10,12,14H2,(H,27,28)(H2,25,26,29)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 1.20E+3n/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
The compound was tested for inhibition of specific binding of [3H]-SQ 29,548 to thromboxane A2 receptor in human platelet membranes


J Med Chem 34: 2882-91 (1991)


Article DOI: 10.1021/jm00113a030
BindingDB Entry DOI: 10.7270/Q2CJ8CFZ
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50010073
PNG
(3-(2-{3-[(E)-Phenylcarbamoylmethylimino-amino]-7-o...)
Show SMILES OC(=O)CCc1ccccc1CC1C2CCC(O2)C1C=NNC(=O)Nc1ccccc1
Show InChI InChI=1S/C24H27N3O4/c28-23(29)13-10-16-6-4-5-7-17(16)14-19-20(22-12-11-21(19)31-22)15-25-27-24(30)26-18-8-2-1-3-9-18/h1-9,15,19-22H,10-14H2,(H,28,29)(H2,26,27,30)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 1n/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
The compound was tested for inhibition of specific binding of [3H]-SQ 29,548 to thromboxane A2 receptor in human platelet membranes


J Med Chem 34: 2882-91 (1991)


Article DOI: 10.1021/jm00113a030
BindingDB Entry DOI: 10.7270/Q2CJ8CFZ
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50010074
PNG
(CHEMBL99041 | [3-(5-oxabicyclo[2.2.1],3-formaldehy...)
Show SMILES OC(=O)Cc1cccc(CC2C3CCC(O3)C2C=NNC(=O)Nc2ccccc2)c1
Show InChI InChI=1S/C23H25N3O4/c27-22(28)13-16-6-4-5-15(11-16)12-18-19(21-10-9-20(18)30-21)14-24-26-23(29)25-17-7-2-1-3-8-17/h1-8,11,14,18-21H,9-10,12-13H2,(H,27,28)(H2,25,26,29)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 171n/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
The compound was tested for inhibition of specific binding of [3H]-SQ 29,548 to thromboxane A2 receptor in human platelet membranes


J Med Chem 34: 2882-91 (1991)


Article DOI: 10.1021/jm00113a030
BindingDB Entry DOI: 10.7270/Q2CJ8CFZ
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50010077
PNG
(4-[2-(5-oxabicyclo[2.2.1],3-formaldehyde (anilinoc...)
Show SMILES OC(=O)CCCc1ccccc1CC1C2CCC(O2)C1C=NNC(=O)Nc1ccccc1
Show InChI InChI=1S/C25H29N3O4/c29-24(30)12-6-9-17-7-4-5-8-18(17)15-20-21(23-14-13-22(20)32-23)16-26-28-25(31)27-19-10-2-1-3-11-19/h1-5,7-8,10-11,16,20-23H,6,9,12-15H2,(H,29,30)(H2,27,28,31)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 21n/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
The compound was tested for inhibition of specific binding of [3H]-SQ 29,548 to thromboxane A2 receptor in human platelet membranes


J Med Chem 34: 2882-91 (1991)


Article DOI: 10.1021/jm00113a030
BindingDB Entry DOI: 10.7270/Q2CJ8CFZ
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50010076
PNG
(CHEMBL99348 | {3-[2-(5-oxabicyclo[2.2.1],3-formald...)
Show SMILES OC(=O)Cc1cccc(CCC2C3CCC(O3)C2C=NNC(=O)Nc2ccccc2)c1
Show InChI InChI=1S/C24H27N3O4/c28-23(29)14-17-6-4-5-16(13-17)9-10-19-20(22-12-11-21(19)31-22)15-25-27-24(30)26-18-7-2-1-3-8-18/h1-8,13,15,19-22H,9-12,14H2,(H,28,29)(H2,26,27,30)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 1.07E+3n/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
The compound was tested for inhibition of specific binding of [3H]-SQ 29,548 to thromboxane A2 receptor in human platelet membranes


J Med Chem 34: 2882-91 (1991)


Article DOI: 10.1021/jm00113a030
BindingDB Entry DOI: 10.7270/Q2CJ8CFZ
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50010075
PNG
((5Z)-7-(5-oxabicyclo[2.2.1],3-formaldehyde (anilin...)
Show SMILES OC(=O)CCC\C=C/CC1C2CCC(O2)C1C=NNC(=O)Nc1ccccc1
Show InChI InChI=1S/C21H27N3O4/c25-20(26)11-7-2-1-6-10-16-17(19-13-12-18(16)28-19)14-22-24-21(27)23-15-8-4-3-5-9-15/h1,3-6,8-9,14,16-19H,2,7,10-13H2,(H,25,26)(H2,23,24,27)/b6-1-,22-14?
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 39n/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
The compound was tested for inhibition of specific binding of [3H]-SQ 29,548 to thromboxane A2 receptor in human platelet membranes


J Med Chem 34: 2882-91 (1991)


Article DOI: 10.1021/jm00113a030
BindingDB Entry DOI: 10.7270/Q2CJ8CFZ
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50010078
PNG
(CHEMBL95884 | [2-(5-oxabicyclo[2.2.1],3-formaldehy...)
Show SMILES OC(=O)COc1ccccc1CC1C2CCC(O2)C1C=NNC(=O)Nc1ccccc1
Show InChI InChI=1S/C23H25N3O5/c27-22(28)14-30-19-9-5-4-6-15(19)12-17-18(21-11-10-20(17)31-21)13-24-26-23(29)25-16-7-2-1-3-8-16/h1-9,13,17-18,20-21H,10-12,14H2,(H,27,28)(H2,25,26,29)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 6n/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
The compound was tested for inhibition of specific binding of [3H]-SQ 29,548 to thromboxane A2 receptor in human platelet membranes


J Med Chem 34: 2882-91 (1991)


Article DOI: 10.1021/jm00113a030
BindingDB Entry DOI: 10.7270/Q2CJ8CFZ
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 93 total )  |  Next  |  Last  >>
Jump to: