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Compile Data Set for Download or QSAR

Found 369 hits with Last Name = 'jeong' and Initial = 'ys'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50474740
PNG
(CHEMBL355074)
Show SMILES CCCCc1ccc(cc1)C1=C(OC(C)(C)C1=O)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C23H26O4S/c1-5-6-7-16-8-10-17(11-9-16)20-21(27-23(2,3)22(20)24)18-12-14-19(15-13-18)28(4,25)26/h8-15H,5-7H2,1-4H3
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n/an/a 5.02n/an/an/an/an/an/a



AmorePacific R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method


J Med Chem 47: 792-804 (2004)

More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50474747
PNG
(CHEMBL167357)
Show SMILES CC1(C)OC(=C(C1=O)c1cc(F)cc(F)c1)c1ccc(cc1F)S(N)(=O)=O
Show InChI InChI=1S/C18H14F3NO4S/c1-18(2)17(23)15(9-5-10(19)7-11(20)6-9)16(26-18)13-4-3-12(8-14(13)21)27(22,24)25/h3-8H,1-2H3,(H2,22,24,25)
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n/an/a 7.55n/an/an/an/an/an/a



AmorePacific R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method


J Med Chem 47: 792-804 (2004)

More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50474743
PNG
(CHEMBL353935)
Show SMILES CC1(C)OC(=C(C1=O)c1cccc(F)c1)c1ccc(cc1F)S(N)(=O)=O
Show InChI InChI=1S/C18H15F2NO4S/c1-18(2)17(22)15(10-4-3-5-11(19)8-10)16(25-18)13-7-6-12(9-14(13)20)26(21,23)24/h3-9H,1-2H3,(H2,21,23,24)
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n/an/a 7.91n/an/an/an/an/an/a



AmorePacific R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method


J Med Chem 47: 792-804 (2004)

More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50474760
PNG
(CG-100649 | CG100649 | POLMACOXIB | Polmacoxib)
Show SMILES CC1(C)OC(=C(C1=O)c1cccc(F)c1)c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C18H16FNO4S/c1-18(2)17(21)15(12-4-3-5-13(19)10-12)16(24-18)11-6-8-14(9-7-11)25(20,22)23/h3-10H,1-2H3,(H2,20,22,23)
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n/an/a 8.30n/an/an/an/an/an/a



AmorePacific R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method


J Med Chem 47: 792-804 (2004)

More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus (rat))
BDBM50170264
PNG
(CHEMBL361931 | N-{4-[3-(4-tert-Butyl-benzyl)-thiou...)
Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)c(Cl)c2)cc1
Show InChI InChI=1S/C20H26ClN3O2S2/c1-20(2,3)16-8-5-14(6-9-16)12-22-19(27)23-13-15-7-10-18(17(21)11-15)24-28(4,25)26/h5-11,24H,12-13H2,1-4H3,(H2,22,23,27)
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n/an/a 8.40n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Inhibitory effect on capsaicin (0.5 uM)-induced calcium uptake in rat DRG neurons upon incubation at RT for 10 minutes


J Med Chem 48: 5823-36 (2005)


Article DOI: 10.1021/jm0502790
BindingDB Entry DOI: 10.7270/Q2057FGN
More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50224228
PNG
(CHEMBL46233)
Show SMILES CC(C)(C)C(=O)OCc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)c(F)c1)C(C)(C)C
Show InChI InChI=1S/C26H36FN3O4S2/c1-25(2,3)20-10-9-18(19(13-20)16-34-23(31)26(4,5)6)15-29-24(35)28-14-17-8-11-22(21(27)12-17)30-36(7,32)33/h8-13,30H,14-16H2,1-7H3,(H2,28,29,35)
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n/an/a 15n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons


Bioorg Med Chem Lett 14: 1693-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.041
BindingDB Entry DOI: 10.7270/Q23B6294
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50474737
PNG
(CHEMBL167011)
Show SMILES CC1(C)OC(=C(C1=O)c1ccc(F)c(F)c1)c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C18H15F2NO4S/c1-18(2)17(22)15(11-5-8-13(19)14(20)9-11)16(25-18)10-3-6-12(7-4-10)26(21,23)24/h3-9H,1-2H3,(H2,21,23,24)
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n/an/a 18.5n/an/an/an/an/an/a



AmorePacific R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method


J Med Chem 47: 792-804 (2004)

More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50224175
PNG
(CHEMBL48061)
Show SMILES CCCCOc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)c(F)c1)C(C)(C)C
Show InChI InChI=1S/C24H34FN3O3S2/c1-6-7-12-31-22-14-19(24(2,3)4)10-9-18(22)16-27-23(32)26-15-17-8-11-21(20(25)13-17)28-33(5,29)30/h8-11,13-14,28H,6-7,12,15-16H2,1-5H3,(H2,26,27,32)
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n/an/a 20n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons


Bioorg Med Chem Lett 14: 1693-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.041
BindingDB Entry DOI: 10.7270/Q23B6294
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50474742
PNG
(CHEMBL166295)
Show SMILES CC1(C)OC(=C(C1=O)c1ccccc1)c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C18H17NO4S/c1-18(2)17(20)15(12-6-4-3-5-7-12)16(23-18)13-8-10-14(11-9-13)24(19,21)22/h3-11H,1-2H3,(H2,19,21,22)
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n/an/a 23.3n/an/an/an/an/an/a



AmorePacific R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method


J Med Chem 47: 792-804 (2004)

More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus (rat))
BDBM50304771
PNG
(3-(4-tert-Butylphenyl)-N-[3-fluoro-4-(methylsulfon...)
Show SMILES CC(C)(C)c1ccc(CCC(=O)NCc2cc(F)c(NS(C)(=O)=O)c(C=C)c2)cc1
Show InChI InChI=1S/C23H29FN2O3S/c1-6-18-13-17(14-20(24)22(18)26-30(5,28)29)15-25-21(27)12-9-16-7-10-19(11-8-16)23(2,3)4/h6-8,10-11,13-14,26H,1,9,12,15H2,2-5H3,(H,25,27)
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n/an/a 25n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neurons assessed as inhibition of capsaicin-induced [45]Ca2+ uptake


Bioorg Med Chem 17: 8149-60 (2009)


Article DOI: 10.1016/j.bmc.2009.10.043
BindingDB Entry DOI: 10.7270/Q2NV9JBN
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50218963
PNG
(CHEMBL297626)
Show SMILES CC1(C)OC(=C(C1=O)c1cccc(Cl)c1)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C19H17ClO4S/c1-19(2)18(21)16(13-5-4-6-14(20)11-13)17(24-19)12-7-9-15(10-8-12)25(3,22)23/h4-11H,1-3H3
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n/an/a 26.5n/an/an/an/an/an/a



AmorePacific R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method


J Med Chem 47: 792-804 (2004)

More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50474770
PNG
(CHEMBL353965)
Show SMILES CC1(C)OC(=C(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C19H16F3NO4S/c1-18(2)17(24)15(12-4-3-5-13(10-12)19(20,21)22)16(27-18)11-6-8-14(9-7-11)28(23,25)26/h3-10H,1-2H3,(H2,23,25,26)
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n/an/a 26.7n/an/an/an/an/an/a



AmorePacific R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method


J Med Chem 47: 792-804 (2004)

More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus (rat))
BDBM50304776
PNG
(3-(4-tert-Butylphenyl)-N-[3-cyano-5-fluoro-4-(meth...)
Show SMILES CC(C)(C)c1ccc(CCC(=S)NCc2cc(F)c(NS(C)(=O)=O)c(c2)C#N)cc1
Show InChI InChI=1S/C22H26FN3O2S2/c1-22(2,3)18-8-5-15(6-9-18)7-10-20(29)25-14-16-11-17(13-24)21(19(23)12-16)26-30(4,27)28/h5-6,8-9,11-12,26H,7,10,14H2,1-4H3,(H,25,29)
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n/an/a 28n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neurons assessed as inhibition of capsaicin-induced [45]Ca2+ uptake


Bioorg Med Chem 17: 8149-60 (2009)


Article DOI: 10.1016/j.bmc.2009.10.043
BindingDB Entry DOI: 10.7270/Q2NV9JBN
More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50224176
PNG
(CHEMBL296963)
Show SMILES NC(=O)N1CCN(CC1)c1ccccn1
Show InChI InChI=1S/C10H14N4O/c11-10(15)14-7-5-13(6-8-14)9-3-1-2-4-12-9/h1-4H,5-8H2,(H2,11,15)
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n/an/a 30n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons


Bioorg Med Chem Lett 14: 1693-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.041
BindingDB Entry DOI: 10.7270/Q23B6294
More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus (rat))
BDBM50160028
PNG
(CHEMBL180138 | N-(4-tert-Butyl-phenyl)-4-(3-methyl...)
Show SMILES Cc1cccnc1-c1ccc(cc1)C(=O)Nc1ccc(cc1)C(C)(C)C
Show InChI InChI=1S/C23H24N2O/c1-16-6-5-15-24-21(16)17-7-9-18(10-8-17)22(26)25-20-13-11-19(12-14-20)23(2,3)4/h5-15H,1-4H3,(H,25,26)
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n/an/a 31n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
In vitro antagonistic activity on VR1 receptor in [Ca2+] influx assay in rat dorsal root ganglion


Bioorg Med Chem Lett 15: 631-4 (2005)


Article DOI: 10.1016/j.bmcl.2004.11.033
BindingDB Entry DOI: 10.7270/Q25T3JZR
More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus (rat))
BDBM50160036
PNG
(CHEMBL183121 | N-(4-tert-Butyl-phenyl)-4-pyridin-2...)
Show SMILES CC(C)(C)c1ccc(NC(=O)c2ccc(cc2)-c2ccccn2)cc1
Show InChI InChI=1S/C22H22N2O/c1-22(2,3)18-11-13-19(14-12-18)24-21(25)17-9-7-16(8-10-17)20-6-4-5-15-23-20/h4-15H,1-3H3,(H,24,25)
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n/an/a 31n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
In vitro antagonistic activity on VR1 receptor in [Ca2+] influx assay in rat dorsal root ganglion


Bioorg Med Chem Lett 15: 631-4 (2005)


Article DOI: 10.1016/j.bmcl.2004.11.033
BindingDB Entry DOI: 10.7270/Q25T3JZR
More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus (rat))
BDBM50304770
PNG
(3-(4-tert-Butylphenyl)-N-[3-fluoro-4-(methylsulfon...)
Show SMILES CC(C)(C)c1ccc(CCC(=S)NCc2cc(F)c(NS(C)(=O)=O)c(C=C)c2)cc1
Show InChI InChI=1S/C23H29FN2O2S2/c1-6-18-13-17(14-20(24)22(18)26-30(5,27)28)15-25-21(29)12-9-16-7-10-19(11-8-16)23(2,3)4/h6-8,10-11,13-14,26H,1,9,12,15H2,2-5H3,(H,25,29)
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n/an/a 32n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neurons assessed as inhibition of capsaicin-induced [45]Ca2+ uptake


Bioorg Med Chem 17: 8149-60 (2009)


Article DOI: 10.1016/j.bmc.2009.10.043
BindingDB Entry DOI: 10.7270/Q2NV9JBN
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50474765
PNG
(CHEMBL353959)
Show SMILES CC(=O)c1ccc(cc1)C1=C(OC(C)(C)C1=O)c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C20H19NO5S/c1-12(22)13-4-6-14(7-5-13)17-18(26-20(2,3)19(17)23)15-8-10-16(11-9-15)27(21,24)25/h4-11H,1-3H3,(H2,21,24,25)
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n/an/a 33.7n/an/an/an/an/an/a



AmorePacific R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method


J Med Chem 47: 792-804 (2004)

More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus (rat))
BDBM20321
PNG
(3-[(4-tert-butylphenyl)methyl]-1-[(3-fluoro-4-meth...)
Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)c(F)c2)cc1
Show InChI InChI=1S/C20H26FN3O2S2/c1-20(2,3)16-8-5-14(6-9-16)12-22-19(27)23-13-15-7-10-18(17(21)11-15)24-28(4,25)26/h5-11,24H,12-13H2,1-4H3,(H2,22,23,27)
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n/an/a 37n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as reduction of capsaicin-stimulated 45Ca2+ uptake


Bioorg Med Chem 17: 3557-67 (2009)


Article DOI: 10.1016/j.bmc.2009.04.010
BindingDB Entry DOI: 10.7270/Q2V124QJ
More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM20321
PNG
(3-[(4-tert-butylphenyl)methyl]-1-[(3-fluoro-4-meth...)
Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)c(F)c2)cc1
Show InChI InChI=1S/C20H26FN3O2S2/c1-20(2,3)16-8-5-14(6-9-16)12-22-19(27)23-13-15-7-10-18(17(21)11-15)24-28(4,25)26/h5-11,24H,12-13H2,1-4H3,(H2,22,23,27)
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n/an/a 37n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons


Bioorg Med Chem Lett 14: 1693-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.041
BindingDB Entry DOI: 10.7270/Q23B6294
More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus (rat))
BDBM20321
PNG
(3-[(4-tert-butylphenyl)methyl]-1-[(3-fluoro-4-meth...)
Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)c(F)c2)cc1
Show InChI InChI=1S/C20H26FN3O2S2/c1-20(2,3)16-8-5-14(6-9-16)12-22-19(27)23-13-15-7-10-18(17(21)11-15)24-28(4,25)26/h5-11,24H,12-13H2,1-4H3,(H2,22,23,27)
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Seoul National University

Curated by ChEMBL


Assay Description
Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neurons assessed as inhibition of capsaicin-induced [45]Ca2+ uptake


Bioorg Med Chem 17: 8149-60 (2009)


Article DOI: 10.1016/j.bmc.2009.10.043
BindingDB Entry DOI: 10.7270/Q2NV9JBN
More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus (rat))
BDBM20321
PNG
(3-[(4-tert-butylphenyl)methyl]-1-[(3-fluoro-4-meth...)
Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)c(F)c2)cc1
Show InChI InChI=1S/C20H26FN3O2S2/c1-20(2,3)16-8-5-14(6-9-16)12-22-19(27)23-13-15-7-10-18(17(21)11-15)24-28(4,25)26/h5-11,24H,12-13H2,1-4H3,(H2,22,23,27)
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n/an/a 37n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Inhibitory effect on capsaicin (0.5 uM)-induced calcium uptake in rat DRG neurons upon incubation at RT for 10 minutes


J Med Chem 48: 5823-36 (2005)


Article DOI: 10.1021/jm0502790
BindingDB Entry DOI: 10.7270/Q2057FGN
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50474746
PNG
(CHEMBL423083)
Show SMILES CC1(C)OC(=C(C1=O)c1cccc(Cl)c1)c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C18H16ClNO4S/c1-18(2)17(21)15(12-4-3-5-13(19)10-12)16(24-18)11-6-8-14(9-7-11)25(20,22)23/h3-10H,1-2H3,(H2,20,22,23)
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n/an/a 37.1n/an/an/an/an/an/a



AmorePacific R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method


J Med Chem 47: 792-804 (2004)

More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus (rat))
BDBM50160033
PNG
(CHEMBL183795 | N-(4-Isopropyl-phenyl)-4-pyridin-2-...)
Show SMILES CC(C)c1ccc(NC(=O)c2ccc(cc2)-c2ccccn2)cc1
Show InChI InChI=1S/C21H20N2O/c1-15(2)16-10-12-19(13-11-16)23-21(24)18-8-6-17(7-9-18)20-5-3-4-14-22-20/h3-15H,1-2H3,(H,23,24)
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n/an/a 38n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
In vitro antagonistic activity on VR1 receptor in [Ca2+] influx assay in rat dorsal root ganglion


Bioorg Med Chem Lett 15: 631-4 (2005)


Article DOI: 10.1016/j.bmcl.2004.11.033
BindingDB Entry DOI: 10.7270/Q25T3JZR
More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus (rat))
BDBM50304752
PNG
(3-(4-tert-Butylphenyl)-N-[3-fluoro-4-(methylsulfon...)
Show SMILES CC(C)(C)c1ccc(CCC(=S)NCc2ccc(NS(C)(=O)=O)c(F)c2)cc1
Show InChI InChI=1S/C21H27FN2O2S2/c1-21(2,3)17-9-5-15(6-10-17)8-12-20(27)23-14-16-7-11-19(18(22)13-16)24-28(4,25)26/h5-7,9-11,13,24H,8,12,14H2,1-4H3,(H,23,27)
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n/an/a 40n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neurons assessed as inhibition of capsaicin-induced [45]Ca2+ uptake


Bioorg Med Chem 17: 8149-60 (2009)


Article DOI: 10.1016/j.bmc.2009.10.043
BindingDB Entry DOI: 10.7270/Q2NV9JBN
More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus (rat))
BDBM20321
PNG
(3-[(4-tert-butylphenyl)methyl]-1-[(3-fluoro-4-meth...)
Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)c(F)c2)cc1
Show InChI InChI=1S/C20H26FN3O2S2/c1-20(2,3)16-8-5-14(6-9-16)12-22-19(27)23-13-15-7-10-18(17(21)11-15)24-28(4,25)26/h5-11,24H,12-13H2,1-4H3,(H2,22,23,27)
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n/an/a 40n/an/an/an/an/an/a



Sookmyung Women's University

Curated by ChEMBL


Assay Description
Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as reduction of capsaicin-stimulated intracellular 45Ca2+ influx by scintillat...


Bioorg Med Chem 18: 111-6 (2010)


Article DOI: 10.1016/j.bmc.2009.11.014
BindingDB Entry DOI: 10.7270/Q2TQ61NH
More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus (rat))
BDBM50172566
PNG
(CHEMBL196291 | N-{4-[3-(4-tert-Butyl-benzyl)-thiou...)
Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)c(I)c2)cc1
Show InChI InChI=1S/C20H26IN3O2S2/c1-20(2,3)16-8-5-14(6-9-16)12-22-19(27)23-13-15-7-10-18(17(21)11-15)24-28(4,25)26/h5-11,24H,12-13H2,1-4H3,(H2,22,23,27)
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n/an/a 41n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Inhibitory effect on capsaicin (0.5 uM)-induced calcium uptake in rat DRG neurons upon incubation at RT for 10 minutes


J Med Chem 48: 5823-36 (2005)


Article DOI: 10.1021/jm0502790
BindingDB Entry DOI: 10.7270/Q2057FGN
More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus (rat))
BDBM50142759
PNG
((R)-N-(4-(1-(3-(4-tert-butylbenzyl)thioureido)ethy...)
Show SMILES C[C@@H](NC(=S)NCc1ccc(cc1)C(C)(C)C)c1ccc(NS(C)(=O)=O)cc1
Show InChI InChI=1S/C21H29N3O2S2/c1-15(17-8-12-19(13-9-17)24-28(5,25)26)23-20(27)22-14-16-6-10-18(11-7-16)21(2,3)4/h6-13,15,24H,14H2,1-5H3,(H2,22,23,27)/t15-/m1/s1
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n/an/a 50n/an/an/an/an/an/a



Sookmyung Women's University

Curated by ChEMBL


Assay Description
Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as reduction of capsaicin-stimulated intracellular 45Ca2+ influx by scintillat...


Bioorg Med Chem 18: 111-6 (2010)


Article DOI: 10.1016/j.bmc.2009.11.014
BindingDB Entry DOI: 10.7270/Q2TQ61NH
More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus (rat))
BDBM50172563
PNG
(1-(1H-Benzotriazol-5-ylmethyl)-3-(4-tert-butyl-ben...)
Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc3nn[nH]c3c2)cc1
Show InChI InChI=1S/C19H23N5S/c1-19(2,3)15-7-4-13(5-8-15)11-20-18(25)21-12-14-6-9-16-17(10-14)23-24-22-16/h4-10H,11-12H2,1-3H3,(H2,20,21,25)(H,22,23,24)
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n/an/a 50n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Inhibitory effect on capsaicin (0.5 uM)-induced calcium uptake in rat DRG neurons upon incubation at RT for 10 minutes


J Med Chem 48: 5823-36 (2005)


Article DOI: 10.1021/jm0502790
BindingDB Entry DOI: 10.7270/Q2057FGN
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50474771
PNG
(CHEMBL352602)
Show SMILES CC1(C)OC(=C(C1=O)c1cc(F)cc(F)c1)c1ccc(c(F)c1)S(N)(=O)=O
Show InChI InChI=1S/C18H14F3NO4S/c1-18(2)17(23)15(10-5-11(19)8-12(20)6-10)16(26-18)9-3-4-14(13(21)7-9)27(22,24)25/h3-8H,1-2H3,(H2,22,24,25)
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n/an/a 50.3n/an/an/an/an/an/a



AmorePacific R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method


J Med Chem 47: 792-804 (2004)

More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50474766
PNG
(CHEMBL166720)
Show SMILES CC1(C)OC(=C(C1=O)c1cccc(Cl)c1)c1ccc(cc1F)S(C)(=O)=O
Show InChI InChI=1S/C19H16ClFO4S/c1-19(2)18(22)16(11-5-4-6-12(20)9-11)17(25-19)14-8-7-13(10-15(14)21)26(3,23)24/h4-10H,1-3H3
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n/an/a 50.7n/an/an/an/an/an/a



AmorePacific R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method


J Med Chem 47: 792-804 (2004)

More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM11639
PNG
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F
Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)
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n/an/a 52.4n/an/an/an/an/an/a



AmorePacific R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method


J Med Chem 47: 792-804 (2004)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM20321
PNG
(3-[(4-tert-butylphenyl)methyl]-1-[(3-fluoro-4-meth...)
Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)c(F)c2)cc1
Show InChI InChI=1S/C20H26FN3O2S2/c1-20(2,3)16-8-5-14(6-9-16)12-22-19(27)23-13-15-7-10-18(17(21)11-15)24-28(4,25)26/h5-11,24H,12-13H2,1-4H3,(H2,22,23,27)
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n/an/a 54n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Concentration required to inhibit [3H]-RTX radioligand binding towards transient receptor potential cation channel (subfamily V, member 1) expressed ...


J Med Chem 48: 5823-36 (2005)


Article DOI: 10.1021/jm0502790
BindingDB Entry DOI: 10.7270/Q2057FGN
More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus (rat))
BDBM50160039
PNG
(CHEMBL183752 | N-(4-tert-Butyl-phenyl)-4-(3-chloro...)
Show SMILES CC(C)(C)c1ccc(NC(=O)c2ccc(cc2)-c2ncccc2Cl)cc1
Show InChI InChI=1S/C22H21ClN2O/c1-22(2,3)17-10-12-18(13-11-17)25-21(26)16-8-6-15(7-9-16)20-19(23)5-4-14-24-20/h4-14H,1-3H3,(H,25,26)
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n/an/a 55n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
In vitro antagonistic activity on VR1 receptor in [Ca2+] influx assay in rat dorsal root ganglion


Bioorg Med Chem Lett 15: 631-4 (2005)


Article DOI: 10.1016/j.bmcl.2004.11.033
BindingDB Entry DOI: 10.7270/Q25T3JZR
More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus (rat))
BDBM50304761
PNG
(3-(4-tert-Butylphenyl)-N-[3-cyano-4-(methylsulfona...)
Show SMILES CC(C)(C)c1ccc(CCC(=S)NCc2ccc(NS(C)(=O)=O)c(c2)C#N)cc1
Show InChI InChI=1S/C22H27N3O2S2/c1-22(2,3)19-9-5-16(6-10-19)8-12-21(28)24-15-17-7-11-20(18(13-17)14-23)25-29(4,26)27/h5-7,9-11,13,25H,8,12,15H2,1-4H3,(H,24,28)
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n/an/a 55n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neurons assessed as inhibition of capsaicin-induced [45]Ca2+ uptake


Bioorg Med Chem 17: 8149-60 (2009)


Article DOI: 10.1016/j.bmc.2009.10.043
BindingDB Entry DOI: 10.7270/Q2NV9JBN
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50218973
PNG
(CHEMBL44001)
Show SMILES CC1(C)OC(=C(C1=O)c1cccc(F)c1)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C19H17FO4S/c1-19(2)18(21)16(13-5-4-6-14(20)11-13)17(24-19)12-7-9-15(10-8-12)25(3,22)23/h4-11H,1-3H3
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n/an/a 55.5n/an/an/an/an/an/a



AmorePacific R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method


J Med Chem 47: 792-804 (2004)

More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus (rat))
BDBM50258505
PNG
(CHEMBL468512 | N-(3-Cyano-5-fluoro-4-(methylsulfon...)
Show SMILES CC1(C)CCC(C)(C)c2cc(CCC(=O)NCc3cc(F)c(NS(C)(=O)=O)c(c3)C#N)ccc12
Show InChI InChI=1S/C26H32FN3O3S/c1-25(2)10-11-26(3,4)21-13-17(6-8-20(21)25)7-9-23(31)29-16-18-12-19(15-28)24(22(27)14-18)30-34(5,32)33/h6,8,12-14,30H,7,9-11,16H2,1-5H3,(H,29,31)
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n/an/a 57n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as reduction of capsaicin-stimulated 45Ca2+ uptake


Bioorg Med Chem 17: 3557-67 (2009)


Article DOI: 10.1016/j.bmc.2009.04.010
BindingDB Entry DOI: 10.7270/Q2V124QJ
More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50224234
PNG
(CHEMBL45252)
Show SMILES CCCCOc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)cc1)C(C)(C)C
Show InChI InChI=1S/C24H35N3O3S2/c1-6-7-14-30-22-15-20(24(2,3)4)11-10-19(22)17-26-23(31)25-16-18-8-12-21(13-9-18)27-32(5,28)29/h8-13,15,27H,6-7,14,16-17H2,1-5H3,(H2,25,26,31)
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n/an/a 60n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons


Bioorg Med Chem Lett 14: 1693-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.041
BindingDB Entry DOI: 10.7270/Q23B6294
More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50224232
PNG
(CHEMBL296729)
Show SMILES COCCOc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)cc1)C(C)(C)C
Show InChI InChI=1S/C23H33N3O4S2/c1-23(2,3)19-9-8-18(21(14-19)30-13-12-29-4)16-25-22(31)24-15-17-6-10-20(11-7-17)26-32(5,27)28/h6-11,14,26H,12-13,15-16H2,1-5H3,(H2,24,25,31)
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n/an/a 60n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons


Bioorg Med Chem Lett 14: 1693-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.041
BindingDB Entry DOI: 10.7270/Q23B6294
More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50224229
PNG
(CHEMBL48998)
Show SMILES CC(C)(C)COc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)cc1)C(C)(C)C
Show InChI InChI=1S/C25H37N3O3S2/c1-24(2,3)17-31-22-14-20(25(4,5)6)11-10-19(22)16-27-23(32)26-15-18-8-12-21(13-9-18)28-33(7,29)30/h8-14,28H,15-17H2,1-7H3,(H2,26,27,32)
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n/an/a 60n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons


Bioorg Med Chem Lett 14: 1693-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.041
BindingDB Entry DOI: 10.7270/Q23B6294
More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus (rat))
BDBM50160027
PNG
(CHEMBL183045 | N-(4-tert-Butyl-phenyl)-4-(3-nitro-...)
Show SMILES CC(C)(C)c1ccc(NC(=O)c2ccc(cc2)-c2ncccc2[N+]([O-])=O)cc1
Show InChI InChI=1S/C22H21N3O3/c1-22(2,3)17-10-12-18(13-11-17)24-21(26)16-8-6-15(7-9-16)20-19(25(27)28)5-4-14-23-20/h4-14H,1-3H3,(H,24,26)
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n/an/a 60n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
In vitro antagonistic activity on VR1 receptor in [Ca2+] influx assay in rat dorsal root ganglion


Bioorg Med Chem Lett 15: 631-4 (2005)


Article DOI: 10.1016/j.bmcl.2004.11.033
BindingDB Entry DOI: 10.7270/Q25T3JZR
More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus (rat))
BDBM50160030
PNG
(CHEMBL181478 | N-(4-tert-Butyl-phenyl)-4-pyrimidin...)
Show SMILES CC(C)(C)c1ccc(NC(=O)c2ccc(cc2)-c2ncccn2)cc1
Show InChI InChI=1S/C21H21N3O/c1-21(2,3)17-9-11-18(12-10-17)24-20(25)16-7-5-15(6-8-16)19-22-13-4-14-23-19/h4-14H,1-3H3,(H,24,25)
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n/an/a 60n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
In vitro antagonistic activity on VR1 receptor in [Ca2+] influx assay in rat dorsal root ganglion


Bioorg Med Chem Lett 15: 631-4 (2005)


Article DOI: 10.1016/j.bmcl.2004.11.033
BindingDB Entry DOI: 10.7270/Q25T3JZR
More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus (rat))
BDBM50304758
PNG
(3-(4-tert-Butylphenyl)-N-[3-methyl-4-(methylsulfon...)
Show SMILES Cc1cc(CNC(=S)CCc2ccc(cc2)C(C)(C)C)ccc1NS(C)(=O)=O
Show InChI InChI=1S/C22H30N2O2S2/c1-16-14-18(8-12-20(16)24-28(5,25)26)15-23-21(27)13-9-17-6-10-19(11-7-17)22(2,3)4/h6-8,10-12,14,24H,9,13,15H2,1-5H3,(H,23,27)
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n/an/a 60n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neurons assessed as inhibition of capsaicin-induced [45]Ca2+ uptake


Bioorg Med Chem 17: 8149-60 (2009)


Article DOI: 10.1016/j.bmc.2009.10.043
BindingDB Entry DOI: 10.7270/Q2NV9JBN
More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus (rat))
BDBM50304760
PNG
(3-(4-tert-Butylphenyl)-N-[4-(methylsulfonamido)-3-...)
Show SMILES CC(C)(C)c1ccc(CCC(=S)NCc2ccc(NS(C)(=O)=O)c(C=C)c2)cc1
Show InChI InChI=1S/C23H30N2O2S2/c1-6-19-15-18(9-13-21(19)25-29(5,26)27)16-24-22(28)14-10-17-7-11-20(12-8-17)23(2,3)4/h6-9,11-13,15,25H,1,10,14,16H2,2-5H3,(H,24,28)
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n/an/a 61n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neurons assessed as inhibition of capsaicin-induced [45]Ca2+ uptake


Bioorg Med Chem 17: 8149-60 (2009)


Article DOI: 10.1016/j.bmc.2009.10.043
BindingDB Entry DOI: 10.7270/Q2NV9JBN
More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50224196
PNG
(CHEMBL43723)
Show SMILES CC(C)(C)COc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)c(F)c1)C(C)(C)C
Show InChI InChI=1S/C25H36FN3O3S2/c1-24(2,3)16-32-22-13-19(25(4,5)6)10-9-18(22)15-28-23(33)27-14-17-8-11-21(20(26)12-17)29-34(7,30)31/h8-13,29H,14-16H2,1-7H3,(H2,27,28,33)
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n/an/a 66n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons


Bioorg Med Chem Lett 14: 1693-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.041
BindingDB Entry DOI: 10.7270/Q23B6294
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50474741
PNG
(CHEMBL355729)
Show SMILES CCC1(CC)OC(=C(C1=O)c1ccc(cc1)C(F)(F)F)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C22H21F3O4S/c1-4-21(5-2)20(26)18(14-6-10-16(11-7-14)22(23,24)25)19(29-21)15-8-12-17(13-9-15)30(3,27)28/h6-13H,4-5H2,1-3H3
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n/an/a 68.4n/an/an/an/an/an/a



AmorePacific R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method


J Med Chem 47: 792-804 (2004)

More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50224237
PNG
(CHEMBL431341)
Show SMILES CCCCCOc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)cc1)C(C)(C)C
Show InChI InChI=1S/C25H37N3O3S2/c1-6-7-8-15-31-23-16-21(25(2,3)4)12-11-20(23)18-27-24(32)26-17-19-9-13-22(14-10-19)28-33(5,29)30/h9-14,16,28H,6-8,15,17-18H2,1-5H3,(H2,26,27,32)
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n/an/a 70n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons


Bioorg Med Chem Lett 14: 1693-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.041
BindingDB Entry DOI: 10.7270/Q23B6294
More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50224230
PNG
(CHEMBL47282)
Show SMILES CC(C)(C)C(=O)OCc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)cc1)C(C)(C)C
Show InChI InChI=1S/C26H37N3O4S2/c1-25(2,3)21-11-10-19(20(14-21)17-33-23(30)26(4,5)6)16-28-24(34)27-15-18-8-12-22(13-9-18)29-35(7,31)32/h8-14,29H,15-17H2,1-7H3,(H2,27,28,34)
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n/an/a 70n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons


Bioorg Med Chem Lett 14: 1693-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.041
BindingDB Entry DOI: 10.7270/Q23B6294
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50474762
PNG
(CHEMBL166378)
Show SMILES CCC1(C)OC(=C(C1=O)c1cc(Cl)cc(Cl)c1)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C20H18Cl2O4S/c1-4-20(2)19(23)17(13-9-14(21)11-15(22)10-13)18(26-20)12-5-7-16(8-6-12)27(3,24)25/h5-11H,4H2,1-3H3
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n/an/a 70.5n/an/an/an/an/an/a



AmorePacific R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method


J Med Chem 47: 792-804 (2004)

More data for this
Ligand-Target Pair
Vanilloid receptor


(Rattus norvegicus (rat))
BDBM50170263
PNG
(CHEMBL189418 | N-{4-[3-(4-tert-Butyl-benzyl)-thiou...)
Show SMILES CC(C)(C)c1ccc(C[N-]C(=[SH+])NCc2ccc(NS(C)(=O)=O)c(c2)[N+]([O-])=O)cc1
Show InChI InChI=1S/C20H26N4O4S2/c1-20(2,3)16-8-5-14(6-9-16)12-21-19(29)22-13-15-7-10-17(23-30(4,27)28)18(11-15)24(25)26/h5-11,23H,12-13H2,1-4H3,(H2,21,22,29)
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n/an/a 71n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Inhibitory effect on capsaicin (0.5 uM)-induced calcium uptake in rat DRG neurons upon incubation at RT for 10 minutes


J Med Chem 48: 5823-36 (2005)


Article DOI: 10.1021/jm0502790
BindingDB Entry DOI: 10.7270/Q2057FGN
More data for this
Ligand-Target Pair
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