BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 79 hits with Last Name = 'korboukh' and Initial = 'i'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine receptor A1


(Homo sapiens (Human))
BDBM50395123
PNG
(CHEMBL2163560)
Show SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])([O-])=O)n1cnc2c(NC3CCCC3)nc(Cl)nc12
Show InChI InChI=1S/C15H21ClN5O7P/c16-15-19-12(18-7-3-1-2-4-7)9-13(20-15)21(6-17-9)14-11(23)10(22)8(28-14)5-27-29(24,25)26/h6-8,10-11,14,22-23H,1-5H2,(H,18,19,20)(H2,24,25,26)/p-2/t8-,10-,11-,14-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
25n/an/an/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Displacement of [3H]2-chloro-N6-cyclopentyladenosine from human A1AR


J Med Chem 55: 6467-77 (2012)


Article DOI: 10.1021/jm3004834
BindingDB Entry DOI: 10.7270/Q21J9BX3
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))
BDBM50395122
PNG
(CHEMBL2163561)
Show SMILES COP(=O)(OC)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC3CCCC3)nc(Cl)nc12
Show InChI InChI=1S/C17H25ClN5O7P/c1-27-31(26,28-2)29-7-10-12(24)13(25)16(30-10)23-8-19-11-14(20-9-5-3-4-6-9)21-17(18)22-15(11)23/h8-10,12-13,16,24-25H,3-7H2,1-2H3,(H,20,21,22)/t10-,12-,13-,16-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
36n/an/an/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Displacement of [3H]2-chloro-N6-cyclopentyladenosine from human A1AR


J Med Chem 55: 6467-77 (2012)


Article DOI: 10.1021/jm3004834
BindingDB Entry DOI: 10.7270/Q21J9BX3
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))
BDBM50395122
PNG
(CHEMBL2163561)
Show SMILES COP(=O)(OC)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC3CCCC3)nc(Cl)nc12
Show InChI InChI=1S/C17H25ClN5O7P/c1-27-31(26,28-2)29-7-10-12(24)13(25)16(30-10)23-8-19-11-14(20-9-5-3-4-6-9)21-17(18)22-15(11)23/h8-10,12-13,16,24-25H,3-7H2,1-2H3,(H,20,21,22)/t10-,12-,13-,16-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
450n/an/an/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Displacement of [3H]2-chloro-N6-cyclopentyladenosine from human A3AR


J Med Chem 55: 6467-77 (2012)


Article DOI: 10.1021/jm3004834
BindingDB Entry DOI: 10.7270/Q21J9BX3
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))
BDBM50395123
PNG
(CHEMBL2163560)
Show SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])([O-])=O)n1cnc2c(NC3CCCC3)nc(Cl)nc12
Show InChI InChI=1S/C15H21ClN5O7P/c16-15-19-12(18-7-3-1-2-4-7)9-13(20-15)21(6-17-9)14-11(23)10(22)8(28-14)5-27-29(24,25)26/h6-8,10-11,14,22-23H,1-5H2,(H,18,19,20)(H2,24,25,26)/p-2/t8-,10-,11-,14-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.30E+3n/an/an/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Displacement of [3H]2-chloro-N6-cyclopentyladenosine from human A3AR


J Med Chem 55: 6467-77 (2012)


Article DOI: 10.1021/jm3004834
BindingDB Entry DOI: 10.7270/Q21J9BX3
More data for this
Ligand-Target Pair
Adenosine receptor A2


(Homo sapiens (Human))
BDBM50395123
PNG
(CHEMBL2163560)
Show SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])([O-])=O)n1cnc2c(NC3CCCC3)nc(Cl)nc12
Show InChI InChI=1S/C15H21ClN5O7P/c16-15-19-12(18-7-3-1-2-4-7)9-13(20-15)21(6-17-9)14-11(23)10(22)8(28-14)5-27-29(24,25)26/h6-8,10-11,14,22-23H,1-5H2,(H,18,19,20)(H2,24,25,26)/p-2/t8-,10-,11-,14-/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.60E+3n/an/an/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Displacement of [3H]2-chloro-N6-cyclopentyladenosine from human A2AR


J Med Chem 55: 6467-77 (2012)


Article DOI: 10.1021/jm3004834
BindingDB Entry DOI: 10.7270/Q21J9BX3
More data for this
Ligand-Target Pair
Adenosine receptor A2


(Homo sapiens (Human))
BDBM50395122
PNG
(CHEMBL2163561)
Show SMILES COP(=O)(OC)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC3CCCC3)nc(Cl)nc12
Show InChI InChI=1S/C17H25ClN5O7P/c1-27-31(26,28-2)29-7-10-12(24)13(25)16(30-10)23-8-19-11-14(20-9-5-3-4-6-9)21-17(18)22-15(11)23/h8-10,12-13,16,24-25H,3-7H2,1-2H3,(H,20,21,22)/t10-,12-,13-,16-/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
4.70E+3n/an/an/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Displacement of [3H]2-chloro-N6-cyclopentyladenosine from human A2AR


J Med Chem 55: 6467-77 (2012)


Article DOI: 10.1021/jm3004834
BindingDB Entry DOI: 10.7270/Q21J9BX3
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427787
PNG
(CHEMBL2325198)
Show SMILES O=C(NCC(=O)N1CCCCC1)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C14H17N5O2S/c20-13(19-6-2-1-3-7-19)9-15-14(21)16-10-4-5-11-12(8-10)22-18-17-11/h4-5,8H,1-3,6-7,9H2,(H2,15,16,21)
PDB

B.MOAD
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 230n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427778
PNG
(CHEMBL2325177)
Show SMILES [O-][N+](=O)c1ccc(CNC(=O)Nc2ccc3nnsc3c2)cc1
Show InChI InChI=1S/C14H11N5O3S/c20-14(15-8-9-1-4-11(5-2-9)19(21)22)16-10-3-6-12-13(7-10)23-18-17-12/h1-7H,8H2,(H2,15,16,20)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 300n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427788
PNG
(CHEMBL2325197)
Show SMILES Fc1ccc(cc1)C(=O)CNC(=O)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C15H11FN4O2S/c16-10-3-1-9(2-4-10)13(21)8-17-15(22)18-11-5-6-12-14(7-11)23-20-19-12/h1-7H,8H2,(H2,17,18,22)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 360n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427772
PNG
(CHEMBL2325183)
Show SMILES O=C(NCC(=O)c1ccccc1)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C15H12N4O2S/c20-13(10-4-2-1-3-5-10)9-16-15(21)17-11-6-7-12-14(8-11)22-19-18-12/h1-8H,9H2,(H2,16,17,21)
PDB

B.MOAD
GoogleScholar
CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Similars

PDB
Article
PubMed
n/an/a 480n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427790
PNG
(CHEMBL2325195)
Show SMILES OC(CNC(=O)Nc1ccc2nnsc2c1)C1CCCCC1
Show InChI InChI=1S/C15H20N4O2S/c20-13(10-4-2-1-3-5-10)9-16-15(21)17-11-6-7-12-14(8-11)22-19-18-12/h6-8,10,13,20H,1-5,9H2,(H2,16,17,21)
PDB

B.MOAD
GoogleScholar
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 490n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427789
PNG
(CHEMBL2325196)
Show SMILES O=C(NCC(=O)C1CCCCC1)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C15H18N4O2S/c20-13(10-4-2-1-3-5-10)9-16-15(21)17-11-6-7-12-14(8-11)22-19-18-12/h6-8,10H,1-5,9H2,(H2,16,17,21)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 840n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427777
PNG
(CHEMBL2325178)
Show SMILES CS(=O)(=O)c1ccc(CNC(=O)Nc2ccc3nnsc3c2)cc1
Show InChI InChI=1S/C15H14N4O3S2/c1-24(21,22)12-5-2-10(3-6-12)9-16-15(20)17-11-4-7-13-14(8-11)23-19-18-13/h2-8H,9H2,1H3,(H2,16,17,20)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 850n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427767
PNG
(CHEMBL2325442)
Show SMILES O=C(NCCC1CCCCC1)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C15H20N4OS/c20-15(16-9-8-11-4-2-1-3-5-11)17-12-6-7-13-14(10-12)21-19-18-13/h6-7,10-11H,1-5,8-9H2,(H2,16,17,20)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427776
PNG
(CHEMBL2325179)
Show SMILES O=C(NCc1ccc(cc1)C#N)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C15H11N5OS/c16-8-10-1-3-11(4-2-10)9-17-15(21)18-12-5-6-13-14(7-12)22-20-19-13/h1-7H,9H2,(H2,17,18,21)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.80E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427794
PNG
(CHEMBL2325191)
Show SMILES OC(CNC(=O)Nc1ccc2nnsc2c1)c1ccccc1
Show InChI InChI=1S/C15H14N4O2S/c20-13(10-4-2-1-3-5-10)9-16-15(21)17-11-6-7-12-14(8-11)22-19-18-12/h1-8,13,20H,9H2,(H2,16,17,21)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.90E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427771
PNG
(CHEMBL2325184)
Show SMILES Fc1ccc(CCCNC(=O)Nc2ccc3nnsc3c2)cc1
Show InChI InChI=1S/C16H15FN4OS/c17-12-5-3-11(4-6-12)2-1-9-18-16(22)19-13-7-8-14-15(10-13)23-21-20-14/h3-8,10H,1-2,9H2,(H2,18,19,22)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.20E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427768
PNG
(CHEMBL2325441)
Show SMILES O=C(NCCC1=CCCCC1)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C15H18N4OS/c20-15(16-9-8-11-4-2-1-3-5-11)17-12-6-7-13-14(10-12)21-19-18-13/h4,6-7,10H,1-3,5,8-9H2,(H2,16,17,20)
PDB

B.MOAD
GoogleScholar
Purchase

CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Similars

PDB
Article
PubMed
n/an/a 2.40E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427770
PNG
(CHEMBL2325185)
Show SMILES O=C(NCCC1CCNCC1)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C14H19N5OS/c20-14(16-8-5-10-3-6-15-7-4-10)17-11-1-2-12-13(9-11)21-19-18-12/h1-2,9-10,15H,3-8H2,(H2,16,17,20)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.70E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427775
PNG
(CHEMBL2325180)
Show SMILES FC(F)(F)c1ccc(CNC(=O)Nc2ccc3nnsc3c2)cc1
Show InChI InChI=1S/C15H11F3N4OS/c16-15(17,18)10-3-1-9(2-4-10)8-19-14(23)20-11-5-6-12-13(7-11)24-22-21-12/h1-7H,8H2,(H2,19,20,23)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.10E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427791
PNG
(CHEMBL2325194)
Show SMILES OC(CNC(=O)Nc1ccc2nnsc2c1)c1ccccc1F
Show InChI InChI=1S/C15H13FN4O2S/c16-11-4-2-1-3-10(11)13(21)8-17-15(22)18-9-5-6-12-14(7-9)23-20-19-12/h1-7,13,21H,8H2,(H2,17,18,22)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.30E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427796
PNG
(CHEMBL2325189)
Show SMILES O=C(NCCCC1CCNCC1)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C15H21N5OS/c21-15(17-7-1-2-11-5-8-16-9-6-11)18-12-3-4-13-14(10-12)22-20-19-13/h3-4,10-11,16H,1-2,5-9H2,(H2,17,18,21)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.30E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427757
PNG
(CHEMBL2325163)
Show SMILES O=C(NCCC1CCOCC1)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C14H18N4O2S/c19-14(15-6-3-10-4-7-20-8-5-10)16-11-1-2-12-13(9-11)21-18-17-12/h1-2,9-10H,3-8H2,(H2,15,16,19)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.60E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427769
PNG
(CHEMBL2325186)
Show SMILES N[C@H]1CC[C@@H](CCNC(=O)Nc2ccc3nnsc3c2)CC1
Show InChI InChI=1S/C15H21N5OS/c16-11-3-1-10(2-4-11)7-8-17-15(21)18-12-5-6-13-14(9-12)22-20-19-13/h5-6,9-11H,1-4,7-8,16H2,(H2,17,18,21)/t10-,11+
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.60E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427774
PNG
(CHEMBL2325181)
Show SMILES Fc1ccc(CNC(=O)Nc2ccc3nnsc3c2)cc1
Show InChI InChI=1S/C14H11FN4OS/c15-10-3-1-9(2-4-10)8-16-14(20)17-11-5-6-12-13(7-11)21-19-18-12/h1-7H,8H2,(H2,16,17,20)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.00E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427792
PNG
(CHEMBL2325193)
Show SMILES OC(CNC(=O)Nc1ccc2nnsc2c1)c1ccc(F)cc1
Show InChI InChI=1S/C15H13FN4O2S/c16-10-3-1-9(2-4-10)13(21)8-17-15(22)18-11-5-6-12-14(7-11)23-20-19-12/h1-7,13,21H,8H2,(H2,17,18,22)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.40E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427793
PNG
(CHEMBL2325192)
Show SMILES FC(F)(CNC(=O)Nc1ccc2nnsc2c1)c1ccccc1
Show InChI InChI=1S/C15H12F2N4OS/c16-15(17,10-4-2-1-3-5-10)9-18-14(22)19-11-6-7-12-13(8-11)23-21-20-12/h1-8H,9H2,(H2,18,19,22)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427756
PNG
(CHEMBL2325164)
Show SMILES O=C(NCCN1CCCCC1)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C14H19N5OS/c20-14(15-6-9-19-7-2-1-3-8-19)16-11-4-5-12-13(10-11)21-18-17-12/h4-5,10H,1-3,6-9H2,(H2,15,16,20)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.20E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427797
PNG
(CHEMBL2325188)
Show SMILES N[C@H]1CC[C@H](CCCNC(=O)Nc2ccc3nnsc3c2)CC1
Show InChI InChI=1S/C16H23N5OS/c17-12-5-3-11(4-6-12)2-1-9-18-16(22)19-13-7-8-14-15(10-13)23-21-20-14/h7-8,10-12H,1-6,9,17H2,(H2,18,19,22)/t11-,12-
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.30E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427795
PNG
(CHEMBL2325190)
Show SMILES NC(CNC(=O)Nc1ccc2nnsc2c1)c1ccccc1
Show InChI InChI=1S/C15H15N5OS/c16-12(10-4-2-1-3-5-10)9-17-15(21)18-11-6-7-13-14(8-11)22-20-19-13/h1-8,12H,9,16H2,(H2,17,18,21)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.90E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427754
PNG
(CHEMBL2325166)
Show SMILES O=C(NCCCN1CCOCC1)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C14H19N5O2S/c20-14(15-4-1-5-19-6-8-21-9-7-19)16-11-2-3-12-13(10-11)22-18-17-12/h2-3,10H,1,4-9H2,(H2,15,16,20)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.20E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427798
PNG
(CHEMBL2325187)
Show SMILES N[C@H]1CC[C@H](CCNC(=O)Nc2ccc3nnsc3c2)CC1
Show InChI InChI=1S/C15H21N5OS/c16-11-3-1-10(2-4-11)7-8-17-15(21)18-12-5-6-13-14(9-12)22-20-19-13/h5-6,9-11H,1-4,7-8,16H2,(H2,17,18,21)/t10-,11-
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427753
PNG
(CHEMBL2325167)
Show SMILES O=C(NCCN1CCCC1)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C13H17N5OS/c19-13(14-5-8-18-6-1-2-7-18)15-10-3-4-11-12(9-10)20-17-16-11/h3-4,9H,1-2,5-8H2,(H2,14,15,19)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427755
PNG
(CHEMBL2325165)
Show SMILES O=C(NCCN1CCOCC1)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C13H17N5O2S/c19-13(14-3-4-18-5-7-20-8-6-18)15-10-1-2-11-12(9-10)21-17-16-11/h1-2,9H,3-8H2,(H2,14,15,19)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427779
PNG
(CHEMBL2325176)
Show SMILES COc1ccc(CNC(=O)Nc2ccc3nnsc3c2)cc1
Show InChI InChI=1S/C15H14N4O2S/c1-21-12-5-2-10(3-6-12)9-16-15(20)17-11-4-7-13-14(8-11)22-19-18-13/h2-8H,9H2,1H3,(H2,16,17,20)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427781
PNG
(CHEMBL2325174)
Show SMILES O=C(NCc1ccncc1)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C13H11N5OS/c19-13(15-8-9-3-5-14-6-4-9)16-10-1-2-11-12(7-10)20-18-17-11/h1-7H,8H2,(H2,15,16,19)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427785
PNG
(CHEMBL2325170)
Show SMILES CC(C)(C)CCNC(=O)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C13H18N4OS/c1-13(2,3)6-7-14-12(18)15-9-4-5-10-11(8-9)19-17-16-10/h4-5,8H,6-7H2,1-3H3,(H2,14,15,18)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427783
PNG
(CHEMBL2325172)
Show SMILES O=C(NCc1ccccn1)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C13H11N5OS/c19-13(15-8-10-3-1-2-6-14-10)16-9-4-5-11-12(7-9)20-18-17-11/h1-7H,8H2,(H2,15,16,19)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.50E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427782
PNG
(CHEMBL2325173)
Show SMILES O=C(NCc1cccnc1)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C13H11N5OS/c19-13(15-8-9-2-1-5-14-7-9)16-10-3-4-11-12(6-10)20-18-17-11/h1-7H,8H2,(H2,15,16,19)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.50E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427786
PNG
(CHEMBL2325169)
Show SMILES CCNC(=O)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C9H10N4OS/c1-2-10-9(14)11-6-3-4-7-8(5-6)15-13-12-7/h3-5H,2H2,1H3,(H2,10,11,14)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.50E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427780
PNG
(CHEMBL2325175)
Show SMILES CN(C)c1ccc(CNC(=O)Nc2ccc3nnsc3c2)cc1
Show InChI InChI=1S/C16H17N5OS/c1-21(2)13-6-3-11(4-7-13)10-17-16(22)18-12-5-8-14-15(9-12)23-20-19-14/h3-9H,10H2,1-2H3,(H2,17,18,22)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.50E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein G9a (G9a)


(Homo sapiens (Human))
BDBM50427772
PNG
(CHEMBL2325183)
Show SMILES O=C(NCC(=O)c1ccccc1)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C15H12N4O2S/c20-13(10-4-2-1-3-5-10)9-16-15(21)17-11-6-7-12-14(8-11)22-19-18-12/h1-8H,9H2,(H2,16,17,21)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Similars

Article
PubMed
n/an/a 2.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of G9a (unknown origin) using histone H3 (1 to 25) as substrate after 0.25 hrs by scintillation proximity assay in presence of [3H]-S-aden...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Histone-lysine N-methyltransferase SUV39H2 (Suv39H2)


(Homo sapiens (Human))
BDBM50427772
PNG
(CHEMBL2325183)
Show SMILES O=C(NCC(=O)c1ccccc1)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C15H12N4O2S/c20-13(10-4-2-1-3-5-10)9-16-15(21)17-11-6-7-12-14(8-11)22-19-18-12/h1-8H,9H2,(H2,16,17,21)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Similars

Article
PubMed
n/an/a 2.20E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of SUV39H2 (unknown origin) using histone H3 (1 to 25) as substrate after 0.25 hrs by scintillation proximity assay in presence of [3H]-S-...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427784
PNG
(CHEMBL2325171)
Show SMILES O=C(NCc1ccccc1)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C14H12N4OS/c19-14(15-9-10-4-2-1-3-5-10)16-11-6-7-12-13(8-11)20-18-17-12/h1-8H,9H2,(H2,15,16,19)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.50E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1


(Homo sapiens (Human))
BDBM50427772
PNG
(CHEMBL2325183)
Show SMILES O=C(NCC(=O)c1ccccc1)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C15H12N4O2S/c20-13(10-4-2-1-3-5-10)9-16-15(21)17-11-6-7-12-14(8-11)22-19-18-12/h1-8H,9H2,(H2,16,17,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Similars

Article
PubMed
n/an/a 2.50E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of GLP (unknown origin) using histone H3 (1 to 25) as substrate after 0.25 hrs by scintillation proximity assay in presence of [3H]-S-aden...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427773
PNG
(CHEMBL2325182)
Show SMILES FC(F)(F)c1ccccc1CNC(=O)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C15H11F3N4OS/c16-15(17,18)11-4-2-1-3-9(11)8-19-14(23)20-10-5-6-12-13(7-10)24-22-21-12/h1-7H,8H2,(H2,19,20,23)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.50E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427752
PNG
(CHEMBL2325168)
Show SMILES O=C(NCC1CCCCC1)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C14H18N4OS/c19-14(15-9-10-4-2-1-3-5-10)16-11-6-7-12-13(8-11)20-18-17-12/h6-8,10H,1-5,9H2,(H2,15,16,19)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427764
PNG
(CHEMBL2325445)
Show SMILES O=C(NCCC1CCCCC1)Nc1ccc2cn[nH]c2c1
Show InChI InChI=1S/C16H22N4O/c21-16(17-9-8-12-4-2-1-3-5-12)19-14-7-6-13-11-18-20-15(13)10-14/h6-7,10-12H,1-5,8-9H2,(H,18,20)(H2,17,19,21)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427763
PNG
(CHEMBL2325446)
Show SMILES O=C(NCCC1CCCCC1)Nc1ccc2[nH]ncc2c1
Show InChI InChI=1S/C16H22N4O/c21-16(17-9-8-12-4-2-1-3-5-12)19-14-6-7-15-13(10-14)11-18-20-15/h6-7,10-12H,1-5,8-9H2,(H,18,20)(H2,17,19,21)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427762
PNG
(CHEMBL2325447)
Show SMILES O=C(NCCC1CCCCC1)Nc1ccc2[nH]c(=O)oc2c1
Show InChI InChI=1S/C16H21N3O3/c20-15(17-9-8-11-4-2-1-3-5-11)18-12-6-7-13-14(10-12)22-16(21)19-13/h6-7,10-11H,1-5,8-9H2,(H,19,21)(H2,17,18,20)
PDB

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 79 total )  |  Next  |  Last  >>
Jump to: