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Compile Data Set for Download or QSAR

Found 247 hits with Last Name = 'zwicker' and Initial = 'a'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123235
PNG
(US8742110, 3-20)
Show SMILES CCOc1cc(CN2CCC3(CN(C(=O)O3)c3ccc(C(O)=O)c(OC)c3)CC2)cc(OCC)c1-c1ccc(F)cc1
Show InChI InChI=1S/C32H35FN2O7/c1-4-40-27-16-21(17-28(41-5-2)29(27)22-6-8-23(33)9-7-22)19-34-14-12-32(13-15-34)20-35(31(38)42-32)24-10-11-25(30(36)37)26(18-24)39-3/h6-11,16-18H,4-5,12-15,19-20H2,1-3H3,(H,36,37)
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n/an/a 0.129n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123247
PNG
(US8742110, 4-11)
Show SMILES CCOc1cc(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)C(O)=O)CC2)c(cc1C)-c1cc(F)c(F)cc1F
Show InChI InChI=1S/C30H29F3N2O5/c1-3-39-27-13-20(22(12-18(27)2)23-14-25(32)26(33)15-24(23)31)16-34-10-8-30(9-11-34)17-35(29(38)40-30)21-6-4-19(5-7-21)28(36)37/h4-7,12-15H,3,8-11,16-17H2,1-2H3,(H,36,37)
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n/an/a 0.152n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123253
PNG
(US8742110, 4-17)
Show SMILES OC(=O)c1ccc(cc1)N1CC2(CCN(Cc3cc(OC(F)(F)F)ccc3-c3ccc(F)c(F)c3F)CC2)OC1=O
Show InChI InChI=1S/C28H22F6N2O5/c29-22-8-7-21(23(30)24(22)31)20-6-5-19(40-28(32,33)34)13-17(20)14-35-11-9-27(10-12-35)15-36(26(39)41-27)18-3-1-16(2-4-18)25(37)38/h1-8,13H,9-12,14-15H2,(H,37,38)
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n/an/a 0.165n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123270
PNG
(US8742110, 5-6)
Show SMILES COc1cccc2c(OC)cc(CN3CCC4(CN(C(=O)O4)c4ccc(cc4)C(O)=O)CC3)cc12
Show InChI InChI=1S/C27H28N2O6/c1-33-23-5-3-4-21-22(23)14-18(15-24(21)34-2)16-28-12-10-27(11-13-28)17-29(26(32)35-27)20-8-6-19(7-9-20)25(30)31/h3-9,14-15H,10-13,16-17H2,1-2H3,(H,30,31)
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n/an/a 0.172n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123248
PNG
(US8742110, 4-12)
Show SMILES CCOc1cc(CN2CCC3(CN(C(=O)O3)c3ccc(C(O)=O)c(C)c3)CC2)c(cc1C)-c1ccc(F)c(F)c1F
Show InChI InChI=1S/C31H31F3N2O5/c1-4-40-26-15-20(24(14-19(26)3)23-7-8-25(32)28(34)27(23)33)16-35-11-9-31(10-12-35)17-36(30(39)41-31)21-5-6-22(29(37)38)18(2)13-21/h5-8,13-15H,4,9-12,16-17H2,1-3H3,(H,37,38)
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n/an/a 0.188n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123300
PNG
(US8742110, 6-18)
Show SMILES CC(C)n1cc(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)C(O)=O)CC2)c2c(OCc3ccccc3)cccc12
Show InChI InChI=1S/C33H35N3O5/c1-23(2)35-20-26(30-28(35)9-6-10-29(30)40-21-24-7-4-3-5-8-24)19-34-17-15-33(16-18-34)22-36(32(39)41-33)27-13-11-25(12-14-27)31(37)38/h3-14,20,23H,15-19,21-22H2,1-2H3,(H,37,38)
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n/an/a 0.225n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123254
PNG
(US8742110, 4-18)
Show SMILES CCOc1cc(CN2CCC3(CN(C(=O)O3)c3ccc(C(O)=O)c(OC)c3)CC2)c(cc1C)-c1ccc(F)c(F)c1F
Show InChI InChI=1S/C31H31F3N2O6/c1-4-41-25-14-19(23(13-18(25)2)21-7-8-24(32)28(34)27(21)33)16-35-11-9-31(10-12-35)17-36(30(39)42-31)20-5-6-22(29(37)38)26(15-20)40-3/h5-8,13-15H,4,9-12,16-17H2,1-3H3,(H,37,38)
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n/an/a 0.228n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123271
PNG
(US8742110, 5-7)
Show SMILES CCOc1cc(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)C(O)=O)CC2)cc2c(OC)ccc(Cl)c12
Show InChI InChI=1S/C28H29ClN2O6/c1-3-36-24-15-18(14-21-23(35-2)9-8-22(29)25(21)24)16-30-12-10-28(11-13-30)17-31(27(34)37-28)20-6-4-19(5-7-20)26(32)33/h4-9,14-15H,3,10-13,16-17H2,1-2H3,(H,32,33)
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n/an/a 0.233n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123255
PNG
(US8742110, 4-19)
Show SMILES OC(=O)c1ccc(cc1)N1CC2(CCN(Cc3cc4CCCc4cc3-c3cc(F)c(F)cc3F)CC2)OC1=O
Show InChI InChI=1S/C30H27F3N2O4/c31-25-15-27(33)26(32)14-24(25)23-13-20-3-1-2-19(20)12-21(23)16-34-10-8-30(9-11-34)17-35(29(38)39-30)22-6-4-18(5-7-22)28(36)37/h4-7,12-15H,1-3,8-11,16-17H2,(H,36,37)
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n/an/a 0.243n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123296
PNG
(US8742110, 6-14)
Show SMILES CC(C)n1nc(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)C(O)=O)CC2)c2cc(OCc3ccccc3)ccc12
Show InChI InChI=1S/C32H34N4O5/c1-22(2)36-29-13-12-26(40-20-23-6-4-3-5-7-23)18-27(29)28(33-36)19-34-16-14-32(15-17-34)21-35(31(39)41-32)25-10-8-24(9-11-25)30(37)38/h3-13,18,22H,14-17,19-21H2,1-2H3,(H,37,38)
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n/an/a 0.260n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123252
PNG
(US8742110, 4-16)
Show SMILES CC(C)Oc1ccc(c(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)C(O)=O)CC2)c1)-c1cc(F)c(F)cc1F
Show InChI InChI=1S/C30H29F3N2O5/c1-18(2)39-22-7-8-23(24-14-26(32)27(33)15-25(24)31)20(13-22)16-34-11-9-30(10-12-34)17-35(29(38)40-30)21-5-3-19(4-6-21)28(36)37/h3-8,13-15,18H,9-12,16-17H2,1-2H3,(H,36,37)
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n/an/a 0.272n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123277
PNG
(US8742110, 5-13)
Show SMILES Cc1cc(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)C(O)=O)CC2)cc2c1OCCC2(C)C
Show InChI InChI=1S/C27H32N2O5/c1-18-14-19(15-22-23(18)33-13-10-26(22,2)3)16-28-11-8-27(9-12-28)17-29(25(32)34-27)21-6-4-20(5-7-21)24(30)31/h4-7,14-15H,8-13,16-17H2,1-3H3,(H,30,31)
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n/an/a 0.317n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123227
PNG
(US8742110, 3-12)
Show SMILES CCOc1cc(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)-c3nnn[nH]3)CC2)cc(OCC)c1-c1ccc(F)cc1
Show InChI InChI=1S/C31H33FN6O4/c1-3-40-26-17-21(18-27(41-4-2)28(26)22-5-9-24(32)10-6-22)19-37-15-13-31(14-16-37)20-38(30(39)42-31)25-11-7-23(8-12-25)29-33-35-36-34-29/h5-12,17-18H,3-4,13-16,19-20H2,1-2H3,(H,33,34,35,36)
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n/an/a 0.323n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123306
PNG
(US8742110, 6-24)
Show SMILES CC(C)n1cc(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)C(O)=O)CC2)c2cc(ccc12)-c1ccc(F)c(F)c1F
Show InChI InChI=1S/C32H30F3N3O4/c1-19(2)37-17-22(25-15-21(5-10-27(25)37)24-8-9-26(33)29(35)28(24)34)16-36-13-11-32(12-14-36)18-38(31(41)42-32)23-6-3-20(4-7-23)30(39)40/h3-10,15,17,19H,11-14,16,18H2,1-2H3,(H,39,40)
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n/an/a 0.342n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123234
PNG
(US8742110, 3-19)
Show SMILES CCOc1cc(CN2CCC3(CN(C(=O)O3)c3ccc(cc3Cl)C(O)=O)CC2)cc(OCC)c1-c1ccc(F)cc1
Show InChI InChI=1S/C31H32ClFN2O6/c1-3-39-26-15-20(16-27(40-4-2)28(26)21-5-8-23(33)9-6-21)18-34-13-11-31(12-14-34)19-35(30(38)41-31)25-10-7-22(29(36)37)17-24(25)32/h5-10,15-17H,3-4,11-14,18-19H2,1-2H3,(H,36,37)
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n/an/a 0.359n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123264
PNG
(US8742110, 4-28)
Show SMILES CCOc1cc(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)C(O)=O)CC2)c(cc1C)-n1cc(C)cn1
Show InChI InChI=1S/C28H32N4O5/c1-4-36-25-14-22(24(13-20(25)3)32-16-19(2)15-29-32)17-30-11-9-28(10-12-30)18-31(27(35)37-28)23-7-5-21(6-8-23)26(33)34/h5-8,13-16H,4,9-12,17-18H2,1-3H3,(H,33,34)
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n/an/a 0.395n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123257
PNG
(US8742110, 4-21)
Show SMILES CCOc1cc(CN2CCC3(CN(C(=O)O3)c3ccc(cc3F)C(O)=O)CC2)c(cc1C)-c1ccc(F)c(F)c1F
Show InChI InChI=1S/C30H28F4N2O5/c1-3-40-25-14-19(21(12-17(25)2)20-5-6-22(31)27(34)26(20)33)15-35-10-8-30(9-11-35)16-36(29(39)41-30)24-7-4-18(28(37)38)13-23(24)32/h4-7,12-14H,3,8-11,15-16H2,1-2H3,(H,37,38)
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n/an/a 0.397n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123250
PNG
(US8742110, 4-14)
Show SMILES CCOc1cc(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)C(O)=O)CC2)c(cc1C)-c1ccc(F)nc1
Show InChI InChI=1S/C29H30FN3O5/c1-3-37-25-15-22(24(14-19(25)2)21-6-9-26(30)31-16-21)17-32-12-10-29(11-13-32)18-33(28(36)38-29)23-7-4-20(5-8-23)27(34)35/h4-9,14-16H,3,10-13,17-18H2,1-2H3,(H,34,35)
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n/an/a 0.407n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123243
PNG
(US8742110, 4-7)
Show SMILES CCOc1cc(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)C(O)=O)CC2)c(cc1C)-c1ccc(F)c(F)c1F
Show InChI InChI=1S/C30H29F3N2O5/c1-3-39-25-15-20(23(14-18(25)2)22-8-9-24(31)27(33)26(22)32)16-34-12-10-30(11-13-34)17-35(29(38)40-30)21-6-4-19(5-7-21)28(36)37/h4-9,14-15H,3,10-13,16-17H2,1-2H3,(H,36,37)
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n/an/a 0.409n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123179
PNG
(US8742110, 1-28)
Show SMILES CC(C)(C)n1cc(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)C(O)=O)CC2)c(n1)-c1ccc(F)c(Cl)c1
Show InChI InChI=1S/C28H30ClFN4O4/c1-27(2,3)34-16-20(24(31-34)19-6-9-23(30)22(29)14-19)15-32-12-10-28(11-13-32)17-33(26(37)38-28)21-7-4-18(5-8-21)25(35)36/h4-9,14,16H,10-13,15,17H2,1-3H3,(H,35,36)
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n/an/a 0.421n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123272
PNG
(US8742110, 5-8)
Show SMILES CCOc1cc(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)C(O)=O)CC2)cc2cnc(cc12)C(F)(F)F
Show InChI InChI=1S/C27H26F3N3O5/c1-2-37-22-12-17(11-19-14-31-23(13-21(19)22)27(28,29)30)15-32-9-7-26(8-10-32)16-33(25(36)38-26)20-5-3-18(4-6-20)24(34)35/h3-6,11-14H,2,7-10,15-16H2,1H3,(H,34,35)
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n/an/a 0.424n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123236
PNG
(US8742110, 3-21)
Show SMILES CCOc1cc(CN2CCC3(CN(C(=O)O3)c3ccc(cc3F)C(O)=O)CC2)cc(OCC)c1-c1ccc(F)cc1
Show InChI InChI=1S/C31H32F2N2O6/c1-3-39-26-15-20(16-27(40-4-2)28(26)21-5-8-23(32)9-6-21)18-34-13-11-31(12-14-34)19-35(30(38)41-31)25-10-7-22(29(36)37)17-24(25)33/h5-10,15-17H,3-4,11-14,18-19H2,1-2H3,(H,36,37)
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n/an/a 0.437n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123245
PNG
(US8742110, 4-9)
Show SMILES OC(=O)c1ccc(cc1)N1CC2(CCN(Cc3cc(ccc3-c3ccc(F)c(F)c3F)C(F)(F)F)CC2)OC1=O
Show InChI InChI=1S/C28H22F6N2O4/c29-22-8-7-21(23(30)24(22)31)20-6-3-18(28(32,33)34)13-17(20)14-35-11-9-27(10-12-35)15-36(26(39)40-27)19-4-1-16(2-5-19)25(37)38/h1-8,13H,9-12,14-15H2,(H,37,38)
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n/an/a 0.439n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123258
PNG
(US8742110, 4-22)
Show SMILES CCOc1cc(CN2CCC3(CN(C(=O)O3)c3ccc(cc3Cl)C(O)=O)CC2)c(cc1C)-c1ccc(F)c(F)c1F
Show InChI InChI=1S/C30H28ClF3N2O5/c1-3-40-25-14-19(21(12-17(25)2)20-5-6-23(32)27(34)26(20)33)15-35-10-8-30(9-11-35)16-36(29(39)41-30)24-7-4-18(28(37)38)13-22(24)31/h4-7,12-14H,3,8-11,15-16H2,1-2H3,(H,37,38)
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n/an/a 0.468n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123244
PNG
(US8742110, 4-8)
Show SMILES CCOc1cc(CN2CCC3(CN(C(=O)O3)c3ccc(cc3C)C(O)=O)CC2)c(cc1C)-c1ccc(F)c(F)c1F
Show InChI InChI=1S/C31H31F3N2O5/c1-4-40-26-15-21(23(14-19(26)3)22-6-7-24(32)28(34)27(22)33)16-35-11-9-31(10-12-35)17-36(30(39)41-31)25-8-5-20(29(37)38)13-18(25)2/h5-8,13-15H,4,9-12,16-17H2,1-3H3,(H,37,38)
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n/an/a 0.474n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123239
PNG
(US8742110, 4-3)
Show SMILES CCOc1ccc(c(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)C(O)=O)CC2)c1)-c1ccc(F)cc1F
Show InChI InChI=1S/C29H28F2N2O5/c1-2-37-23-8-10-24(25-9-5-21(30)16-26(25)31)20(15-23)17-32-13-11-29(12-14-32)18-33(28(36)38-29)22-6-3-19(4-7-22)27(34)35/h3-10,15-16H,2,11-14,17-18H2,1H3,(H,34,35)
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n/an/a 0.490n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123240
PNG
(US8742110, 4-4)
Show SMILES CCOc1ccc(c(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)C(O)=O)CC2)c1)-c1ccc(F)c(F)c1
Show InChI InChI=1S/C29H28F2N2O5/c1-2-37-23-8-9-24(20-5-10-25(30)26(31)16-20)21(15-23)17-32-13-11-29(12-14-32)18-33(28(36)38-29)22-6-3-19(4-7-22)27(34)35/h3-10,15-16H,2,11-14,17-18H2,1H3,(H,34,35)
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n/an/a 0.502n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123242
PNG
(US8742110, 4-6)
Show SMILES CC(C)Oc1ccc(c(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)C(O)=O)CC2)c1)-c1ccc(F)c(F)c1F
Show InChI InChI=1S/C30H29F3N2O5/c1-18(2)39-22-7-8-23(24-9-10-25(31)27(33)26(24)32)20(15-22)16-34-13-11-30(12-14-34)17-35(29(38)40-30)21-5-3-19(4-6-21)28(36)37/h3-10,15,18H,11-14,16-17H2,1-2H3,(H,36,37)
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n/an/a 0.546n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123307
PNG
(US8742110, 6-25)
Show SMILES CC(C)n1cc(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)C(O)=O)CC2)c2cc(Br)ccc12
Show InChI InChI=1S/C26H28BrN3O4/c1-17(2)29-15-19(22-13-20(27)5-8-23(22)29)14-28-11-9-26(10-12-28)16-30(25(33)34-26)21-6-3-18(4-7-21)24(31)32/h3-8,13,15,17H,9-12,14,16H2,1-2H3,(H,31,32)
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n/an/a 0.550n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123241
PNG
(US8742110, 4-5)
Show SMILES CCOc1ccc(c(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)C(O)=O)CC2)c1)-c1ccc(F)c(F)c1F
Show InChI InChI=1S/C29H27F3N2O5/c1-2-38-21-7-8-22(23-9-10-24(30)26(32)25(23)31)19(15-21)16-33-13-11-29(12-14-33)17-34(28(37)39-29)20-5-3-18(4-6-20)27(35)36/h3-10,15H,2,11-14,16-17H2,1H3,(H,35,36)
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n/an/a 0.556n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123180
PNG
(US8742110, 1-29)
Show SMILES CC(C)(C)n1cc(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)-c3nnn[nH]3)CC2)c(n1)-c1cc(F)c(Cl)cc1F
Show InChI InChI=1S/C28H29ClF2N8O2/c1-27(2,3)39-15-18(24(34-39)20-12-23(31)21(29)13-22(20)30)14-37-10-8-28(9-11-37)16-38(26(40)41-28)19-6-4-17(5-7-19)25-32-35-36-33-25/h4-7,12-13,15H,8-11,14,16H2,1-3H3,(H,32,33,35,36)
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n/an/a 0.582n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123256
PNG
(US8742110, 4-20)
Show SMILES CCOc1cc(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)C(O)=O)CC2)c(cc1C)-c1ccc(nc1)C(F)(F)F
Show InChI InChI=1S/C30H30F3N3O5/c1-3-40-25-15-22(24(14-19(25)2)21-6-9-26(34-16-21)30(31,32)33)17-35-12-10-29(11-13-35)18-36(28(39)41-29)23-7-4-20(5-8-23)27(37)38/h4-9,14-16H,3,10-13,17-18H2,1-2H3,(H,37,38)
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n/an/a 0.632n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123269
PNG
(US8742110, 5-5)
Show SMILES CCOc1cc(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)C(O)=O)CC2)cc2c(OC)cc(Cl)cc12
Show InChI InChI=1S/C28H29ClN2O6/c1-3-36-25-13-18(12-22-23(25)14-20(29)15-24(22)35-2)16-30-10-8-28(9-11-30)17-31(27(34)37-28)21-6-4-19(5-7-21)26(32)33/h4-7,12-15H,3,8-11,16-17H2,1-2H3,(H,32,33)
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n/an/a 0.650n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123266
PNG
(US8742110, 5-2)
Show SMILES CCOc1cc(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)C(O)=O)CC2)cc2c(OC)cccc12
Show InChI InChI=1S/C28H30N2O6/c1-3-35-25-16-19(15-23-22(25)5-4-6-24(23)34-2)17-29-13-11-28(12-14-29)18-30(27(33)36-28)21-9-7-20(8-10-21)26(31)32/h4-10,15-16H,3,11-14,17-18H2,1-2H3,(H,31,32)
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n/an/a 0.704n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123311
PNG
(US8742110, 6-29)
Show SMILES COc1ccc(cc1)-c1nc(sc1CN1CCC2(CN(C(=O)O2)c2ccc(cc2)C(O)=O)CC1)C(C)(C)C
Show InChI InChI=1S/C29H33N3O5S/c1-28(2,3)26-30-24(19-7-11-22(36-4)12-8-19)23(38-26)17-31-15-13-29(14-16-31)18-32(27(35)37-29)21-9-5-20(6-10-21)25(33)34/h5-12H,13-18H2,1-4H3,(H,33,34)
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n/an/a 0.705n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123176
PNG
(US8742110, 1-25)
Show SMILES CC1(C)C2CCC(C2)C1n1cc(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)C(O)=O)CC2)c(n1)-c1ccc(F)c(F)c1F
Show InChI InChI=1S/C33H35F3N4O4/c1-32(2)22-6-3-20(15-22)29(32)40-17-21(28(37-40)24-9-10-25(34)27(36)26(24)35)16-38-13-11-33(12-14-38)18-39(31(43)44-33)23-7-4-19(5-8-23)30(41)42/h4-5,7-10,17,20,22,29H,3,6,11-16,18H2,1-2H3,(H,41,42)
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n/an/a 0.740n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123216
PNG
(US8742110, 3-1)
Show SMILES CCOc1cc(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)C(O)=O)CC2)cc(OCC)c1-c1ccc(F)cc1
Show InChI InChI=1S/C31H33FN2O6/c1-3-38-26-17-21(18-27(39-4-2)28(26)22-5-9-24(32)10-6-22)19-33-15-13-31(14-16-33)20-34(30(37)40-31)25-11-7-23(8-12-25)29(35)36/h5-12,17-18H,3-4,13-16,19-20H2,1-2H3,(H,35,36)
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n/an/a 0.768n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123237
PNG
(US8742110, 4-1)
Show SMILES CCOc1ccc(c(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)C(O)=O)CC2)c1)-c1cc(F)c(F)cc1F
Show InChI InChI=1S/C29H27F3N2O5/c1-2-38-21-7-8-22(23-14-25(31)26(32)15-24(23)30)19(13-21)16-33-11-9-29(10-12-33)17-34(28(37)39-29)20-5-3-18(4-6-20)27(35)36/h3-8,13-15H,2,9-12,16-17H2,1H3,(H,35,36)
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n/an/a 0.793n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123298
PNG
(US8742110, 6-16)
Show SMILES COc1ccc2c(CN3CCC4(CN(C(=O)O4)c4ccc(cc4)C(O)=O)CC3)cn(C(C)C)c2c1
Show InChI InChI=1S/C27H31N3O5/c1-18(2)29-16-20(23-9-8-22(34-3)14-24(23)29)15-28-12-10-27(11-13-28)17-30(26(33)35-27)21-6-4-19(5-7-21)25(31)32/h4-9,14,16,18H,10-13,15,17H2,1-3H3,(H,31,32)
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n/an/a 0.851n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123226
PNG
(US8742110, 3-11)
Show SMILES CCOc1cc(CN2CCC3(CN(C(=O)O3)c3ccc(cn3)C(O)=O)CC2)cc(OCC)c1-c1ccc(F)cc1
Show InChI InChI=1S/C30H32FN3O6/c1-3-38-24-15-20(16-25(39-4-2)27(24)21-5-8-23(31)9-6-21)18-33-13-11-30(12-14-33)19-34(29(37)40-30)26-10-7-22(17-32-26)28(35)36/h5-10,15-17H,3-4,11-14,18-19H2,1-2H3,(H,35,36)
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n/an/a 0.941n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123153
PNG
(US8742110, 1-2)
Show SMILES OC(=O)c1ccc(cc1)N1CC2(CCN(Cc3cn(nc3-c3ccc(F)c(Cl)c3)C3CCCCC3)CC2)OC1=O
Show InChI InChI=1S/C30H32ClFN4O4/c31-25-16-21(8-11-26(25)32)27-22(18-36(33-27)24-4-2-1-3-5-24)17-34-14-12-30(13-15-34)19-35(29(39)40-30)23-9-6-20(7-10-23)28(37)38/h6-11,16,18,24H,1-5,12-15,17,19H2,(H,37,38)
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n/an/a 0.943n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123267
PNG
(US8742110, 5-3)
Show SMILES CCOc1cccc2c(OCC)cc(CN3CCC4(CN(C(=O)O4)c4ccc(cc4)C(O)=O)CC3)cc12
Show InChI InChI=1S/C29H32N2O6/c1-3-35-25-7-5-6-23-24(25)16-20(17-26(23)36-4-2)18-30-14-12-29(13-15-30)19-31(28(34)37-29)22-10-8-21(9-11-22)27(32)33/h5-11,16-17H,3-4,12-15,18-19H2,1-2H3,(H,32,33)
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n/an/a 0.980n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123249
PNG
(US8742110, 4-13)
Show SMILES CCOc1ccc(c(CN2CCC3(CN(C(=O)O3)c3ccc(C(O)=O)c(C)c3)CC2)c1)-c1ccc(F)c(F)c1F
Show InChI InChI=1S/C30H29F3N2O5/c1-3-39-21-5-7-23(24-8-9-25(31)27(33)26(24)32)19(15-21)16-34-12-10-30(11-13-34)17-35(29(38)40-30)20-4-6-22(28(36)37)18(2)14-20/h4-9,14-15H,3,10-13,16-17H2,1-2H3,(H,36,37)
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n/an/a 0.983n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123302
PNG
(US8742110, 6-20)
Show SMILES CCCn1cc(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)C(O)=O)CC2)c2ccc(OC)cc12
Show InChI InChI=1S/C27H31N3O5/c1-3-12-29-17-20(23-9-8-22(34-2)15-24(23)29)16-28-13-10-27(11-14-28)18-30(26(33)35-27)21-6-4-19(5-7-21)25(31)32/h4-9,15,17H,3,10-14,16,18H2,1-2H3,(H,31,32)
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n/an/a 1.06n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123260
PNG
(US8742110, 4-24)
Show SMILES Cc1cc(c(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)C(O)=O)CC2)cc1Cl)-c1cc(F)c(F)cc1F
Show InChI InChI=1S/C28H24ClF3N2O4/c1-16-10-20(21-12-24(31)25(32)13-23(21)30)18(11-22(16)29)14-33-8-6-28(7-9-33)15-34(27(37)38-28)19-4-2-17(3-5-19)26(35)36/h2-5,10-13H,6-9,14-15H2,1H3,(H,35,36)
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n/an/a 1.13n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123233
PNG
(US8742110, 3-18)
Show SMILES CCOc1cc(CN2CCC3(CN(C(=O)O3)c3ccc(C(O)=O)c(F)c3)CC2)cc(OCC)c1-c1ccc(F)cc1
Show InChI InChI=1S/C31H32F2N2O6/c1-3-39-26-15-20(16-27(40-4-2)28(26)21-5-7-22(32)8-6-21)18-34-13-11-31(12-14-34)19-35(30(38)41-31)23-9-10-24(29(36)37)25(33)17-23/h5-10,15-17H,3-4,11-14,18-19H2,1-2H3,(H,36,37)
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n/an/a 1.15n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123231
PNG
(US8742110, 3-16)
Show SMILES CCOc1cc(CN2CCC3(CN(C(=O)O3)c3ccc(cc3C)C(O)=O)CC2)cc(OCC)c1-c1ccc(F)cc1
Show InChI InChI=1S/C32H35FN2O6/c1-4-39-27-17-22(18-28(40-5-2)29(27)23-6-9-25(33)10-7-23)19-34-14-12-32(13-15-34)20-35(31(38)41-32)26-11-8-24(30(36)37)16-21(26)3/h6-11,16-18H,4-5,12-15,19-20H2,1-3H3,(H,36,37)
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n/an/a 1.18n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123224
PNG
(US8742110, 3-9)
Show SMILES CCOc1cc(CN2CCC3(CN(C(=O)O3)c3ccc(C(O)=O)c(Cl)c3)CC2)cc(OCC)c1-c1ccc(F)cc1
Show InChI InChI=1S/C31H32ClFN2O6/c1-3-39-26-15-20(16-27(40-4-2)28(26)21-5-7-22(33)8-6-21)18-34-13-11-31(12-14-34)19-35(30(38)41-31)23-9-10-24(29(36)37)25(32)17-23/h5-10,15-17H,3-4,11-14,18-19H2,1-2H3,(H,36,37)
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n/an/a 1.21n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123279
PNG
(US8742110, 5-15)
Show SMILES CC1(C)CCOc2c(Cl)cc(CN3CCC4(CN(C(=O)O4)c4ccc(cc4)C(O)=O)CC3)cc12
Show InChI InChI=1S/C26H29ClN2O5/c1-25(2)9-12-33-22-20(25)13-17(14-21(22)27)15-28-10-7-26(8-11-28)16-29(24(32)34-26)19-5-3-18(4-6-19)23(30)31/h3-6,13-14H,7-12,15-16H2,1-2H3,(H,30,31)
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n/an/a 1.25n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123184
PNG
(US8742110, 1-33)
Show SMILES OC(=O)c1ccc(cc1)N1CC2(CCN(Cc3cn(nc3-c3cc(F)c(F)cc3F)C3CCCCC3)CC2)OC1=O
Show InChI InChI=1S/C30H31F3N4O4/c31-24-15-26(33)25(32)14-23(24)27-20(17-37(34-27)22-4-2-1-3-5-22)16-35-12-10-30(11-13-35)18-36(29(40)41-30)21-8-6-19(7-9-21)28(38)39/h6-9,14-15,17,22H,1-5,10-13,16,18H2,(H,38,39)
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n/an/a 1.29n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair
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