TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:50% Inhibition of stereospecific [3H]-naltrexone (10e-9 M) binding towards opiate receptor in rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 105nMAssay Description:Tested for effective concentration against cloned human Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataIC50: >9.30E+3nMAssay Description:In vitro binding affinity against cloned human Opioid receptor delta 1 expressed in HEK 293S cellsMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Concentration required to inhibit [3H]naltrexone binding to Opioid receptorsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:In vitro binding affinity against cloned human Opioid receptor kappa 1 expressed in HEK 293S cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.04E+5nMAssay Description:Inhibition of MAMC O-dealkylation mediated by human Cytochrome P450 2D6 expressed in human lymphoblastoid cell lineMore data for this Ligand-Target Pair
TargetSolute carrier family 22 member 1(Homo sapiens (Human))
University Medicine Greifswald
Curated by ChEMBL
University Medicine Greifswald
Curated by ChEMBL
Affinity DataIC50: 2.36E+5nMAssay Description:Inhibition of human OCT1 expressed in HEK293 cells assessed as reduction in ASP+ substrate uptake by microplate reader based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.38E+5nMAssay Description:Inhibition of MAMC O-dealkylation mediated by rat Cytochrome P450 2D2 expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Reverse Proteomics Research Institute
Curated by ChEMBL
Reverse Proteomics Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.02E+5nMAssay Description:Inhibitory concentration against potassium channel HERGMore data for this Ligand-Target Pair
Affinity DataIC50: 1.32E+6nMAssay Description:Inhibition of MAMC O-dealkylation mediated by rat Cytochrome P450 2D1 expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
Affinity DataIC50: 2.22E+6nMAssay Description:Inhibition of MAMC O-dealkylation mediated by rat Cytochrome P450 2D4 expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
Affinity DataIC50: 4.09E+6nMAssay Description:Inhibition of MAMC O-dealkylation mediated by rat Cytochrome P450 2D3 expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair