Found 24 hits of affinity data for UniProtKB/TrEMBL: P44432Target
(Institution) | Ligand | Target
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | pH | Temp
°C |
|---|
Enoyl-ACP Reductase (FabI)
Haemophilus influenzae | indole naphthyridinone 31
((2E)-N-[(1,2-dimethyl-1H-indol-3-yl)methyl]-N-meth...) | GoogleScholar
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CSLS
PC cid
PC sid
| PubMed
| n/a | n/a | 25.0 | n/a | n/a | 6.5 | 30 |
GlaxoSmithKline
|
J Med Chem. 46: 1627-35 (2003)
|
Enoyl-ACP Reductase (FabI)
Haemophilus influenzae | indole naphthyridinone 32
((2E)-N-methyl-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naph...) | GoogleScholar
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CSLS
PC cid
PC sid
| PubMed
| n/a | n/a | 70.0 | n/a | n/a | 6.5 | 30 |
GlaxoSmithKline
|
J Med Chem. 46: 1627-35 (2003)
|
Enoyl-ACP Reductase (FabI)
Haemophilus influenzae | indole naphthyridinone 30
((2E)-N-methyl-N-[(2-methyl-1H-indol-3-yl)methyl]-3...) | GoogleScholar
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CSLS
PC cid
PC sid
| PubMed
| n/a | n/a | 130.0 | n/a | n/a | 6.5 | 30 |
GlaxoSmithKline
|
J Med Chem. 46: 1627-35 (2003)
|
Enoyl-ACP Reductase (FabI)
Haemophilus influenzae | indole naphthyridinone 29
((2E)-N-methyl-N-[(1-methyl-1H-indol-3-yl)methyl]-3...) | GoogleScholar
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
| B.MOAD
CSLS
DrugBank
MMDB
PC cid
PC sid
PDB
| PubMed
| n/a | n/a | 390.0 | n/a | n/a | 6.5 | 30 |
GlaxoSmithKline
|
J Med Chem. 46: 1627-35 (2003)
|
Enoyl-ACP Reductase (FabI)
Haemophilus influenzae | indole naphthyridinone 21
((2E)-N-methyl-N-[(1-methyl-1H-indol-2-yl)methyl]-3...) | GoogleScholar
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CSLS
PC cid
PC sid
| PubMed
| n/a | n/a | 560.0 | n/a | n/a | 6.5 | 30 |
GlaxoSmithKline
|
J Med Chem. 46: 1627-35 (2003)
|
Enoyl-ACP Reductase (FabI)
Haemophilus influenzae | Acetamido deriv. 12
((2E)-3-(6-acetamidopyridin-3-yl)-N-methyl-N-[(1-me...) | GoogleScholar
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CSLS
PC cid
PC sid
| PubMed
| n/a | n/a | 1300.0 | n/a | n/a | 6.5 | 30 |
GlaxoSmithKline
|
J Med Chem. 46: 1627-35 (2003)
|
Enoyl-ACP Reductase (FabI)
Haemophilus influenzae | 1,4-Benzodiazepine deriv. 4
(N,4-Dimethyl-N-(1-methyl-1H-indol-2-ylmethyl)-3-ox...) | GoogleScholar
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CSLS
PC cid
PC sid
| PubMed
| n/a | n/a | 2500.0 | n/a | n/a | 6.5 | 30 |
GlaxoSmithKline
|
J Med Chem. 45: 3246-56 (2002)
|
Enoyl-ACP Reductase (FabI)
Haemophilus influenzae | benzamide deriv. 7
(4-Amino-N-methyl-N-(1-methyl-1H-indol-2-ylmethyl)-...) | GoogleScholar
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CSLS
PC cid
PC sid
| PubMed
| n/a | n/a | 2600.0 | n/a | n/a | 6.5 | 30 |
GlaxoSmithKline
|
J Med Chem. 45: 3246-56 (2002)
|
Enoyl-ACP Reductase (FabI)
Haemophilus influenzae | Piperidine 11
((2E)-N-methyl-N-[(1-methyl-1H-indol-2-yl)methyl]-3...) | GoogleScholar
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CSLS
PC cid
PC sid
| PubMed
| n/a | n/a | 2700.0 | n/a | n/a | 6.5 | 30 |
GlaxoSmithKline
|
J Med Chem. 46: 1627-35 (2003)
|
Enoyl-ACP Reductase (FabI)
Haemophilus influenzae | aminopyridine deriv. 9
((2E)-3-(6-aminopyridin-3-yl)-N-methyl-N-[(1-methyl...) | GoogleScholar
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
| B.MOAD
CSLS
DrugBank
PC cid
PC sid
PDB
| PubMed
| n/a | n/a | 4200.0 | n/a | n/a | 6.5 | 30 |
GlaxoSmithKline
|
J Med Chem. 45: 3246-56 (2002)
|
Enoyl-ACP Reductase (FabI)
Haemophilus influenzae | aminopyridine deriv. 9
((2E)-3-(6-aminopyridin-3-yl)-N-methyl-N-[(1-methyl...) | GoogleScholar
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
| B.MOAD
CSLS
DrugBank
PC cid
PC sid
PDB
| PubMed
| n/a | n/a | 4200.0 | n/a | n/a | 6.5 | 30 |
GlaxoSmithKline
|
J Med Chem. 46: 1627-35 (2003)
|
Enoyl-ACP Reductase (FabI)
Haemophilus influenzae | aminopyrimidine deriv. 10
((2E)-3-(2-aminopyrimidin-5-yl)-N-methyl-N-[(1-meth...) | GoogleScholar
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CSLS
PC cid
PC sid
| PubMed
| n/a | n/a | 4300.0 | n/a | n/a | 6.5 | 30 |
GlaxoSmithKline
|
J Med Chem. 45: 3246-56 (2002)
|
Enoyl-ACP Reductase (FabI)
Haemophilus influenzae | benzamide deriv. 5
(3-[(N-Acetyl-N-methylamino)methyl]-4-amino-N-methy...) | GoogleScholar
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
| B.MOAD
CSLS
DrugBank
MMDB
PC cid
PC sid
PDB
| PubMed
| n/a | n/a | 4700.0 | n/a | n/a | 6.5 | 30 |
GlaxoSmithKline
|
J Med Chem. 45: 3246-56 (2002)
|
Enoyl-ACP Reductase (FabI)
Haemophilus influenzae | 1,4-Benzodiazepine deriv. 2
((2R)-2-[(Carbomethoxy)methyl]-N,4-dimethyl-N-(1-me...) | GoogleScholar
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CSLS
PC cid
PC sid
| PubMed
| n/a | n/a | 5100.0 | n/a | n/a | 6.5 | 30 |
GlaxoSmithKline
|
J Med Chem. 45: 3246-56 (2002)
|
Enoyl-ACP Reductase (FabI)
Haemophilus influenzae | aminopyridine 5
((2E)-3-(6-amino-5-methylpyridin-3-yl)-N-methyl-N-[...) | GoogleScholar
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CSLS
PC cid
PC sid
| PubMed
| n/a | n/a | 6100.0 | n/a | n/a | 6.5 | 30 |
GlaxoSmithKline
|
J Med Chem. 46: 1627-35 (2003)
|
Enoyl-ACP Reductase (FabI)
Haemophilus influenzae | 1,4-Benzodiazepine deriv. 1
(methyl 2-(4-methyl-7-{methyl[(1-methyl-1H-indol-2-...) | GoogleScholar
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CSLS
PC cid
PC sid
| PubMed
| n/a | n/a | 6900.0 | n/a | n/a | 6.5 | 30 |
GlaxoSmithKline
|
J Med Chem. 45: 3246-56 (2002)
|
Enoyl-ACP Reductase (FabI)
Haemophilus influenzae | Acetamido deriv. 13
((2E)-3-(6-acetamido-5-methylpyridin-3-yl)-N-methyl...) | GoogleScholar
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CSLS
PC cid
PC sid
| PubMed
| n/a | n/a | 7600.0 | n/a | n/a | 6.5 | 30 |
GlaxoSmithKline
|
J Med Chem. 46: 1627-35 (2003)
|
Enoyl-ACP Reductase (FabI)
Haemophilus influenzae | acrylamide deriv. 13
((2E)-3-(4-aminophenyl)-N-methyl-N-[(1-methyl-1H-in...) | GoogleScholar
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CSLS
PC cid
PC sid
| PubMed
| n/a | n/a | 9000.0 | n/a | n/a | 6.5 | 30 |
GlaxoSmithKline
|
J Med Chem. 45: 3246-56 (2002)
|
Enoyl-ACP Reductase (FabI)
Haemophilus influenzae | aminopyridine deriv. 14
((2E)-N-methyl-N-[(1-methyl-1H-indol-2-yl)methyl]-3...) | GoogleScholar
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CSLS
PC cid
PC sid
| PubMed
| n/a | n/a | 15200.0 | n/a | n/a | 6.5 | 30 |
GlaxoSmithKline
|
J Med Chem. 45: 3246-56 (2002)
|
Enoyl-ACP Reductase (FabI)
Haemophilus influenzae | aminopyridine deriv. 12
(6-Amino-N-methyl-N-(1-methyl-1H-indol-2-yl)nicotin...) | GoogleScholar
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CSLS
PC cid
PC sid
| PubMed
| n/a | n/a | 19200.0 | n/a | n/a | 6.5 | 30 |
GlaxoSmithKline
|
J Med Chem. 45: 3246-56 (2002)
|
Enoyl-ACP Reductase (FabI)
Haemophilus influenzae | aminopyridine deriv. 11
(3-(6-Aminopyridin-3-yl)-N-methyl-N-[(1-methyl-1H-i...) | GoogleScholar
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CSLS
MMDB
PC cid
PC sid
| PubMed
| n/a | n/a | 97400.0 | n/a | n/a | 6.5 | 30 |
GlaxoSmithKline
|
J Med Chem. 45: 3246-56 (2002)
|
Enoyl-ACP Reductase (FabI)
Haemophilus influenzae | benzamide deriv. 8
(N-Methyl-N-(1-methyl-1H-indol-2-ylmethyl)benzamide...) | GoogleScholar
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CSLS
PC cid
PC sid
| PubMed
| n/a | n/a | >100000.0 | n/a | n/a | 6.5 | 30 |
GlaxoSmithKline
|
J Med Chem. 45: 3246-56 (2002)
|
Enoyl-ACP Reductase (FabI)
Haemophilus influenzae | 1,4-Benzodiazepine deriv. 3
((2S)-2-[(Carbomethoxy)methyl]-N,4-dimethyl-N-(1-me...) | GoogleScholar
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CSLS
PC cid
PC sid
| PubMed
| n/a | n/a | >100000.0 | n/a | n/a | 6.5 | 30 |
GlaxoSmithKline
|
J Med Chem. 45: 3246-56 (2002)
|
Enoyl-ACP Reductase (FabI)
Haemophilus influenzae | benzamide deriv. 6
(3-[(N-Acetyl-N-methylamino)methyl]-N-methyl-N-(1-m...) | GoogleScholar
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CSLS
PC cid
PC sid
| PubMed
| n/a | n/a | 121000.0 | n/a | n/a | 6.5 | 30 |
GlaxoSmithKline
|
J Med Chem. 45: 3246-56 (2002)
|
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