BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 49 hits of non-affinity data for polymerid = 1129,384   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monoamine oxidase


(Rattus norvegicus (rat))
BDBM19164
PNG
(3-phenyl-5H-indeno[1,2-c]pyridazin-5-one | Aza-het...)
Show SMILES O=C1c2ccccc2-c2nnc(cc12)-c1ccccc1
Show InChI InChI=1S/C17H10N2O/c20-17-13-9-5-4-8-12(13)16-14(17)10-15(18-19-16)11-6-2-1-3-7-11/h1-10H
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a7.437



University of Bari



Assay Description
A continuous spectrophotometric assay that monitors the rate of oxidation of the nonselective MAO substrate kynuramine into 4-hydroxyquinoline was us...


J Med Chem 50: 5364-71 (2007)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29191
PNG
(3-carboxamido coumarin, 41)
Show SMILES O=C(NC1CCCCC1)c1cc2ccc(OCc3ccccc3)cc2oc1=O
Show InChI InChI=1S/C23H23NO4/c25-22(24-18-9-5-2-6-10-18)20-13-17-11-12-19(14-21(17)28-23(20)26)27-15-16-7-3-1-4-8-16/h1,3-4,7-8,11-14,18H,2,5-6,9-10,15H2,(H,24,25)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 1935-42 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase


(Rattus norvegicus (rat))
BDBM19167
PNG
(3-(phenoxymethyl)-5H-indeno[1,2-c]pyridazin-5-one ...)
Show SMILES O=C1c2ccccc2-c2nnc(COc3ccccc3)cc12
Show InChI InChI=1S/C18H12N2O2/c21-18-15-9-5-4-8-14(15)17-16(18)10-12(19-20-17)11-22-13-6-2-1-3-7-13/h1-10H,11H2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a7.437



University of Bari



Assay Description
A continuous spectrophotometric assay that monitors the rate of oxidation of the nonselective MAO substrate kynuramine into 4-hydroxyquinoline was us...


J Med Chem 50: 5364-71 (2007)

More data for this
Ligand-Target Pair
Monoamine oxidase


(Rattus norvegicus (rat))
BDBM19168
PNG
(3-(4-fluorophenoxymethyl)-5H-indeno[1,2-c]pyridazi...)
Show SMILES Fc1ccc(OCc2cc3C(=O)c4ccccc4-c3nn2)cc1
Show InChI InChI=1S/C18H11FN2O2/c19-11-5-7-13(8-6-11)23-10-12-9-16-17(21-20-12)14-3-1-2-4-15(14)18(16)22/h1-9H,10H2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a7.437



University of Bari



Assay Description
A continuous spectrophotometric assay that monitors the rate of oxidation of the nonselective MAO substrate kynuramine into 4-hydroxyquinoline was us...


J Med Chem 50: 5364-71 (2007)

More data for this
Ligand-Target Pair
Monoamine oxidase


(Rattus norvegicus (rat))
BDBM19169
PNG
(3-[4-(trifluoromethyl)phenoxymethyl]-5H-indeno[1,2...)
Show SMILES FC(F)(F)c1ccc(OCc2cc3C(=O)c4ccccc4-c3nn2)cc1
Show InChI InChI=1S/C19H11F3N2O2/c20-19(21,22)11-5-7-13(8-6-11)26-10-12-9-16-17(24-23-12)14-3-1-2-4-15(14)18(16)25/h1-9H,10H2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a7.437



University of Bari



Assay Description
A continuous spectrophotometric assay that monitors the rate of oxidation of the nonselective MAO substrate kynuramine into 4-hydroxyquinoline was us...


J Med Chem 50: 5364-71 (2007)

More data for this
Ligand-Target Pair
Monoamine oxidase


(Rattus norvegicus (rat))
BDBM19173
PNG
(2-phenyl-2H,3H,5H-indeno[1,2-c]pyridazine-3,5-dion...)
Show SMILES O=C1c2ccccc2-c2nn(-c3ccccc3)c(=O)cc12
Show InChI InChI=1S/C17H10N2O2/c20-15-10-14-16(12-8-4-5-9-13(12)17(14)21)18-19(15)11-6-2-1-3-7-11/h1-10H
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/an/an/an/a7.437



University of Bari



Assay Description
A continuous spectrophotometric assay that monitors the rate of oxidation of the nonselective MAO substrate kynuramine into 4-hydroxyquinoline was us...


J Med Chem 50: 5364-71 (2007)

More data for this
Ligand-Target Pair
Monoamine oxidase


(Rattus norvegicus (rat))
BDBM19177
PNG
(2-(3-nitrophenyl)-9H-indeno[2,1-d]pyrimidin-9-one ...)
Show SMILES [O-][N+](=O)c1cccc(c1)-c1ncc2-c3ccccc3C(=O)c2n1
Show InChI InChI=1S/C17H9N3O3/c21-16-13-7-2-1-6-12(13)14-9-18-17(19-15(14)16)10-4-3-5-11(8-10)20(22)23/h1-9H
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a7.437



University of Bari



Assay Description
A continuous spectrophotometric assay that monitors the rate of oxidation of the nonselective MAO substrate kynuramine into 4-hydroxyquinoline was us...


J Med Chem 50: 5364-71 (2007)

More data for this
Ligand-Target Pair
Monoamine oxidase


(Rattus norvegicus (rat))
BDBM19181
PNG
(3-phenyl-4aH,9H,9aH-indeno[1,2-e][1,2,4]triazin-9-...)
Show SMILES O=C1c2ccccc2-c2nc(nnc12)-c1ccccc1
Show InChI InChI=1S/C16H9N3O/c20-15-12-9-5-4-8-11(12)13-14(15)18-19-16(17-13)10-6-2-1-3-7-10/h1-9H
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a7.437



University of Bari



Assay Description
A continuous spectrophotometric assay that monitors the rate of oxidation of the nonselective MAO substrate kynuramine into 4-hydroxyquinoline was us...


J Med Chem 50: 5364-71 (2007)

More data for this
Ligand-Target Pair
Monoamine oxidase


(Rattus norvegicus (rat))
BDBM19182
PNG
(3-(3-aminophenyl)-4aH,9H,9aH-indeno[1,2-e][1,2,4]t...)
Show SMILES Nc1cccc(c1)-c1nnc2C(=O)c3ccccc3-c2n1
Show InChI InChI=1S/C16H10N4O/c17-10-5-3-4-9(8-10)16-18-13-11-6-1-2-7-12(11)15(21)14(13)19-20-16/h1-8H,17H2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a7.437



University of Bari



Assay Description
A continuous spectrophotometric assay that monitors the rate of oxidation of the nonselective MAO substrate kynuramine into 4-hydroxyquinoline was us...


J Med Chem 50: 5364-71 (2007)

More data for this
Ligand-Target Pair
Monoamine oxidase


(Rattus norvegicus (rat))
BDBM19183
PNG
(3-(3-nitrophenyl)-4aH,9H,9aH-indeno[1,2-e][1,2,4]t...)
Show SMILES [O-][N+](=O)c1cccc(c1)-c1nnc2C(=O)c3ccccc3-c2n1
Show InChI InChI=1S/C16H8N4O3/c21-15-12-7-2-1-6-11(12)13-14(15)18-19-16(17-13)9-4-3-5-10(8-9)20(22)23/h1-8H
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a7.437



University of Bari



Assay Description
A continuous spectrophotometric assay that monitors the rate of oxidation of the nonselective MAO substrate kynuramine into 4-hydroxyquinoline was us...


J Med Chem 50: 5364-71 (2007)

More data for this
Ligand-Target Pair
Monoamine oxidase


(Rattus norvegicus (rat))
BDBM19184
PNG
(3-(3-nitrophenyl)-4aH,5H,9bH-indeno[2,1-e][1,2,4]t...)
Show SMILES [O-][N+](=O)c1cccc(c1)-c1nnc2-c3ccccc3C(=O)c2n1
Show InChI InChI=1S/C16H8N4O3/c21-15-12-7-2-1-6-11(12)13-14(15)17-16(19-18-13)9-4-3-5-10(8-9)20(22)23/h1-8H
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/an/an/an/a7.437



University of Bari



Assay Description
A continuous spectrophotometric assay that monitors the rate of oxidation of the nonselective MAO substrate kynuramine into 4-hydroxyquinoline was us...


J Med Chem 50: 5364-71 (2007)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29137
PNG
(substituted chalcone, 5a)
Show SMILES CC(C)=CCOc1ccc(C(=O)\C=C\c2ccccc2)c(O)c1
Show InChI InChI=1S/C20H20O3/c1-15(2)12-13-23-17-9-10-18(20(22)14-17)19(21)11-8-16-6-4-3-5-7-16/h3-12,14,22H,13H2,1-2H3/b11-8+
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 2818-24 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29138
PNG
(substituted chalcone, 5b)
Show SMILES CC(C)=CCOc1ccc(C(=O)\C=C\c2ccc(C)cc2)c(O)c1
Show InChI InChI=1S/C21H22O3/c1-15(2)12-13-24-18-9-10-19(21(23)14-18)20(22)11-8-17-6-4-16(3)5-7-17/h4-12,14,23H,13H2,1-3H3/b11-8+
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 2818-24 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29149
PNG
(substituted chalcone, 5c)
Show SMILES COc1ccc(\C=C\C(=O)c2ccc(OCC=C(C)C)cc2O)cc1
Show InChI InChI=1S/C21H22O4/c1-15(2)12-13-25-18-9-10-19(21(23)14-18)20(22)11-6-16-4-7-17(24-3)8-5-16/h4-12,14,23H,13H2,1-3H3/b11-6+
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 2818-24 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29150
PNG
(substituted chalcone, 5d)
Show SMILES CC(C)=CCOc1ccc(C(=O)\C=C\c2ccc(OCc3ccccc3)cc2)c(O)c1
Show InChI InChI=1S/C27H26O4/c1-20(2)16-17-30-24-13-14-25(27(29)18-24)26(28)15-10-21-8-11-23(12-9-21)31-19-22-6-4-3-5-7-22/h3-16,18,29H,17,19H2,1-2H3/b15-10+
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 2818-24 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29139
PNG
(substituted chalcone, 5e)
Show SMILES CC(C)=CCOc1ccc(C(=O)\C=C\c2ccc(Cl)cc2)c(O)c1
Show InChI InChI=1S/C20H19ClO3/c1-14(2)11-12-24-17-8-9-18(20(23)13-17)19(22)10-5-15-3-6-16(21)7-4-15/h3-11,13,23H,12H2,1-2H3/b10-5+
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 2818-24 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29151
PNG
(substituted chalcone, 5f)
Show SMILES Clc1ccc(\C=C\C(=O)c2ccc(OCc3ccccc3)cc2)cc1
Show InChI InChI=1S/C22H17ClO2/c23-20-11-6-17(7-12-20)8-15-22(24)19-9-13-21(14-10-19)25-16-18-4-2-1-3-5-18/h1-15H,16H2/b15-8+
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 2818-24 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29140
PNG
(substituted chalcone, 5g)
Show SMILES COc1ccc(cc1)C(=O)\C=C\c1ccc(Cl)cc1
Show InChI InChI=1S/C16H13ClO2/c1-19-15-9-5-13(6-10-15)16(18)11-4-12-2-7-14(17)8-3-12/h2-11H,1H3/b11-4+
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 2818-24 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29141
PNG
(substituted chalcone, 5h)
Show SMILES COc1ccc(cc1)C(=O)\C=C\c1ccc(OCc2ccccc2)cc1
Show InChI InChI=1S/C23H20O3/c1-25-21-14-10-20(11-15-21)23(24)16-9-18-7-12-22(13-8-18)26-17-19-5-3-2-4-6-19/h2-16H,17H2,1H3/b16-9+
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 2818-24 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29142
PNG
(substituted chalcone, 5i)
Show SMILES COc1ccc(C(=O)\C=C\c2ccc(Cl)cc2)c(O)c1
Show InChI InChI=1S/C16H13ClO3/c1-20-13-7-8-14(16(19)10-13)15(18)9-4-11-2-5-12(17)6-3-11/h2-10,19H,1H3/b9-4+
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/an/an/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 2818-24 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29143
PNG
(CHEMBL7976 | Chalcone 1 | Chalcone, 13 | cid_63776...)
Show SMILES O=C(\C=C\c1ccccc1)c1ccccc1
Show InChI InChI=1S/C15H12O/c16-15(14-9-5-2-6-10-14)12-11-13-7-3-1-4-8-13/h1-12H/b12-11+
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 2818-24 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29144
PNG
(substituted chalcone, 5k)
Show SMILES Oc1ccccc1C(=O)\C=C\c1ccc(Cl)cc1
Show InChI InChI=1S/C15H11ClO2/c16-12-8-5-11(6-9-12)7-10-15(18)13-3-1-2-4-14(13)17/h1-10,17H/b10-7+
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 2818-24 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29145
PNG
(substituted chalcone, 5l)
Show SMILES Oc1ccc(cc1)C(=O)\C=C\c1ccc(Cl)cc1
Show InChI InChI=1S/C15H11ClO2/c16-13-6-1-11(2-7-13)3-10-15(18)12-4-8-14(17)9-5-12/h1-10,17H/b10-3+
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 2818-24 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29146
PNG
(substituted chalcone, 5n)
Show SMILES Oc1cc(F)ccc1C(=O)\C=C\c1ccc(Cl)cc1
Show InChI InChI=1S/C15H10ClFO2/c16-11-4-1-10(2-5-11)3-8-14(18)13-7-6-12(17)9-15(13)19/h1-9,19H/b8-3+
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 2818-24 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29147
PNG
(substituted chalcone, 5o)
Show SMILES Fc1ccc(cc1)C(=O)\C=C\c1ccc(OCc2ccccc2)cc1
Show InChI InChI=1S/C22H17FO2/c23-20-11-9-19(10-12-20)22(24)15-8-17-6-13-21(14-7-17)25-16-18-4-2-1-3-5-18/h1-15H,16H2/b15-8+
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 2818-24 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29148
PNG
(substituted chalcone, 5p)
Show SMILES CS(=O)(=O)c1ccc(cc1)C(=O)\C=C\c1ccc(Cl)cc1
Show InChI InChI=1S/C16H13ClO3S/c1-21(19,20)15-9-5-13(6-10-15)16(18)11-4-12-2-7-14(17)8-3-12/h2-11H,1H3/b11-4+
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/an/an/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 2818-24 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29152
PNG
(3-carboxamido coumarin, 1)
Show SMILES O=C(NC1CCCCC1)c1cc2ccccc2oc1=O
Show InChI InChI=1S/C16H17NO3/c18-15(17-12-7-2-1-3-8-12)13-10-11-6-4-5-9-14(11)20-16(13)19/h4-6,9-10,12H,1-3,7-8H2,(H,17,18)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a7.437



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 1935-42 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29153
PNG
(3-carboxamido coumarin, 2)
Show SMILES CC(C)NC(=O)c1cc2ccccc2oc1=O
Show InChI InChI=1S/C13H13NO3/c1-8(2)14-12(15)10-7-9-5-3-4-6-11(9)17-13(10)16/h3-8H,1-2H3,(H,14,15)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/an/an/an/a7.437



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 1935-42 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29154
PNG
(3-carboxamido coumarin, 3)
Show SMILES CC(C)CNC(=O)c1cc2ccccc2oc1=O
Show InChI InChI=1S/C14H15NO3/c1-9(2)8-15-13(16)11-7-10-5-3-4-6-12(10)18-14(11)17/h3-7,9H,8H2,1-2H3,(H,15,16)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a7.437



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 1935-42 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29156
PNG
(3-carboxamido coumarin, 5)
Show SMILES NCCNC(=O)c1cc2ccccc2oc1=O
Show InChI InChI=1S/C12H12N2O3/c13-5-6-14-11(15)9-7-8-3-1-2-4-10(8)17-12(9)16/h1-4,7H,5-6,13H2,(H,14,15)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a7.437



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 1935-42 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29157
PNG
(3-carboxamido coumarin, 7)
Show SMILES O=C(Nc1ccccc1Cc1ccccc1)c1cc2ccccc2oc1=O
Show InChI InChI=1S/C23H17NO3/c25-22(19-15-18-11-5-7-13-21(18)27-23(19)26)24-20-12-6-4-10-17(20)14-16-8-2-1-3-9-16/h1-13,15H,14H2,(H,24,25)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a7.437



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 1935-42 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29159
PNG
(3-carboxamido coumarin, 9)
Show SMILES COc1cccc(NC(=O)c2cc3ccccc3oc2=O)c1
Show InChI InChI=1S/C17H13NO4/c1-21-13-7-4-6-12(10-13)18-16(19)14-9-11-5-2-3-8-15(11)22-17(14)20/h2-10H,1H3,(H,18,19)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a7.437



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 1935-42 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29160
PNG
(3-carboxamido coumarin, 10)
Show SMILES Fc1cccc(NC(=O)c2cc3ccccc3oc2=O)c1
Show InChI InChI=1S/C16H10FNO3/c17-11-5-3-6-12(9-11)18-15(19)13-8-10-4-1-2-7-14(10)21-16(13)20/h1-9H,(H,18,19)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a7.437



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 1935-42 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29161
PNG
(3-carboxamido coumarin, 11)
Show SMILES FC(F)(F)c1cccc(NC(=O)c2cc3ccccc3oc2=O)c1
Show InChI InChI=1S/C17H10F3NO3/c18-17(19,20)11-5-3-6-12(9-11)21-15(22)13-8-10-4-1-2-7-14(10)24-16(13)23/h1-9H,(H,21,22)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/an/an/an/a7.437



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 1935-42 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29166
PNG
(3-carboxamido coumarin, 16)
Show SMILES COc1ccc(NC(=O)c2cc3ccccc3oc2=O)cc1
Show InChI InChI=1S/C17H13NO4/c1-21-13-8-6-12(7-9-13)18-16(19)14-10-11-4-2-3-5-15(11)22-17(14)20/h2-10H,1H3,(H,18,19)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/an/an/an/a7.437



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 1935-42 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29172
PNG
(3-carboxamido coumarin, 22)
Show SMILES Oc1ccc(NC(=O)c2cc3ccccc3oc2=O)cc1
Show InChI InChI=1S/C16H11NO4/c18-12-7-5-11(6-8-12)17-15(19)13-9-10-3-1-2-4-14(10)21-16(13)20/h1-9,18H,(H,17,19)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a7.437



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 1935-42 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29173
PNG
(3-carboxamido coumarin, 23)
Show SMILES Cc1cccc(Cl)c1NC(=O)c1cc2ccccc2oc1=O
Show InChI InChI=1S/C17H12ClNO3/c1-10-5-4-7-13(18)15(10)19-16(20)12-9-11-6-2-3-8-14(11)22-17(12)21/h2-9H,1H3,(H,19,20)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a7.437



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 1935-42 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29183
PNG
(3-carboxamido coumarin, 33)
Show SMILES Fc1c(F)c(F)c(NC(=O)c2cc3ccccc3oc2=O)c(F)c1F
Show InChI InChI=1S/C16H6F5NO3/c17-9-10(18)12(20)14(13(21)11(9)19)22-15(23)7-5-6-3-1-2-4-8(6)25-16(7)24/h1-5H,(H,22,23)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 1935-42 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29186
PNG
(3-carboxamido coumarin, 36)
Show SMILES O=C(NCc1ccccc1)c1cc2ccccc2oc1=O
Show InChI InChI=1S/C17H13NO3/c19-16(18-11-12-6-2-1-3-7-12)14-10-13-8-4-5-9-15(13)21-17(14)20/h1-10H,11H2,(H,18,19)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 1935-42 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29187
PNG
(3-carboxamido coumarin, 37)
Show SMILES O=C(NCCc1ccccc1)c1cc2ccccc2oc1=O
Show InChI InChI=1S/C18H15NO3/c20-17(19-11-10-13-6-2-1-3-7-13)15-12-14-8-4-5-9-16(14)22-18(15)21/h1-9,12H,10-11H2,(H,19,20)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 1935-42 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29188
PNG
(3-carboxamido coumarin, 38)
Show SMILES CN(C(=O)c1cc2ccccc2oc1=O)c1ccccc1
Show InChI InChI=1S/C17H13NO3/c1-18(13-8-3-2-4-9-13)16(19)14-11-12-7-5-6-10-15(12)21-17(14)20/h2-11H,1H3
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 1935-42 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29189
PNG
(3-carboxamido coumarin, 39)
Show SMILES CN(Cc1ccccc1)C(=O)c1cc2ccccc2oc1=O
Show InChI InChI=1S/C18H15NO3/c1-19(12-13-7-3-2-4-8-13)17(20)15-11-14-9-5-6-10-16(14)22-18(15)21/h2-11H,12H2,1H3
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 1935-42 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29190
PNG
(3-carboxamido coumarin, 40)
Show SMILES O=C(N(c1ccccc1)c1ccccc1)c1cc2ccccc2oc1=O
Show InChI InChI=1S/C22H15NO3/c24-21(19-15-16-9-7-8-14-20(16)26-22(19)25)23(17-10-3-1-4-11-17)18-12-5-2-6-13-18/h1-15H
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 1935-42 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29198
PNG
(3-carboxamido coumarin, 48)
Show SMILES COc1ccc(NC(=O)c2cc3ccc(OCc4ccccc4)cc3oc2=O)cc1OC
Show InChI InChI=1S/C25H21NO6/c1-29-21-11-9-18(13-23(21)30-2)26-24(27)20-12-17-8-10-19(14-22(17)32-25(20)28)31-15-16-6-4-3-5-7-16/h3-14H,15H2,1-2H3,(H,26,27)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 1935-42 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29200
PNG
(3-carboxamido coumarin, 50)
Show SMILES O=C(NCc1ccccc1)c1cc2ccc(OCc3ccccc3)cc2oc1=O
Show InChI InChI=1S/C24H19NO4/c26-23(25-15-17-7-3-1-4-8-17)21-13-19-11-12-20(14-22(19)29-24(21)27)28-16-18-9-5-2-6-10-18/h1-14H,15-16H2,(H,25,26)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 1935-42 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29207
PNG
(3-carboxamido coumarin, 57)
Show SMILES CC(C)c1ccc(NC(=O)c2cc3ccc(OCc4ccc(F)cc4)cc3oc2=O)cc1
Show InChI InChI=1S/C26H22FNO4/c1-16(2)18-5-10-21(11-6-18)28-25(29)23-13-19-7-12-22(14-24(19)32-26(23)30)31-15-17-3-8-20(27)9-4-17/h3-14,16H,15H2,1-2H3,(H,28,29)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 1935-42 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29208
PNG
(3-carboxamido coumarin, 58)
Show SMILES CN(C(=O)c1cc2ccc(OCc3ccccc3)cc2oc1=O)c1ccccc1
Show InChI InChI=1S/C24H19NO4/c1-25(19-10-6-3-7-11-19)23(26)21-14-18-12-13-20(15-22(18)29-24(21)27)28-16-17-8-4-2-5-9-17/h2-15H,16H2,1H3
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 1935-42 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase type A (MAO-A)


(Homo sapiens (Human))
BDBM29155
PNG
(3-carboxamido coumarin, 4)
Show SMILES O=C(NCC#C)c1cc2ccccc2oc1=O
Show InChI InChI=1S/C13H9NO3/c1-2-7-14-12(15)10-8-9-5-3-4-6-11(9)17-13(10)16/h1,3-6,8H,7H2,(H,14,15)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a7.437



Universita degli Studi di Roma La Sapienza



Assay Description
The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...


J Med Chem 52: 1935-42 (2009)

More data for this
Ligand-Target Pair
Monoamine oxidase


(Rattus norvegicus (rat))
BDBM19166
PNG
(3-phenyl-5H-pyridazino[4,3-b]indole | Aza-heterocy...)
Show SMILES c1ccc(cc1)-c1cc2[nH]c3ccccc3c2nn1
Show InChI InChI=1S/C16H11N3/c1-2-6-11(7-3-1)14-10-15-16(19-18-14)12-8-4-5-9-13(12)17-15/h1-10,17H
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a7.437



University of Bari



Assay Description
A continuous spectrophotometric assay that monitors the rate of oxidation of the nonselective MAO substrate kynuramine into 4-hydroxyquinoline was us...


J Med Chem 50: 5364-71 (2007)

More data for this
Ligand-Target Pair