Compile Data Set for Download or QSAR

Found 49 hits of non-affinity data for polymerid = 1129,384   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoamine oxidase (Rattus norvegicus (rat))	BDBM19164 (3-phenyl-5H-indeno[1,2-c]pyridazin-5-one | Aza-het...) Show SMILES O=C1c2ccccc2-c2nnc(cc12)-c1ccccc1 Show InChI InChI=1S/C17H10N2O/c20-17-13-9-5-4-8-12(13)16-14(17)10-15(18-19-16)11-6-2-1-3-7-11/h1-10H	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	37
University of Bari					Assay Description A continuous spectrophotometric assay that monitors the rate of oxidation of the nonselective MAO substrate kynuramine into 4-hydroxyquinoline was us...				J Med Chem 50: 5364-71 (2007)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29208 (3-carboxamido coumarin, 58) Show SMILES CN(C(=O)c1cc2ccc(OCc3ccccc3)cc2oc1=O)c1ccccc1 Show InChI InChI=1S/C24H19NO4/c1-25(19-10-6-3-7-11-19)23(26)21-14-18-12-13-20(15-22(18)29-24(21)27)28-16-17-8-4-2-5-9-17/h2-15H,16H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 1935-42 (2009)
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM19167 (3-(phenoxymethyl)-5H-indeno[1,2-c]pyridazin-5-one ...) Show SMILES O=C1c2ccccc2-c2nnc(COc3ccccc3)cc12 Show InChI InChI=1S/C18H12N2O2/c21-18-15-9-5-4-8-14(15)17-16(18)10-12(19-20-17)11-22-13-6-2-1-3-7-13/h1-10H,11H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	37
University of Bari					Assay Description A continuous spectrophotometric assay that monitors the rate of oxidation of the nonselective MAO substrate kynuramine into 4-hydroxyquinoline was us...				J Med Chem 50: 5364-71 (2007)
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM19168 (3-(4-fluorophenoxymethyl)-5H-indeno[1,2-c]pyridazi...) Show SMILES Fc1ccc(OCc2cc3C(=O)c4ccccc4-c3nn2)cc1 Show InChI InChI=1S/C18H11FN2O2/c19-11-5-7-13(8-6-11)23-10-12-9-16-17(21-20-12)14-3-1-2-4-15(14)18(16)22/h1-9H,10H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	37
University of Bari					Assay Description A continuous spectrophotometric assay that monitors the rate of oxidation of the nonselective MAO substrate kynuramine into 4-hydroxyquinoline was us...				J Med Chem 50: 5364-71 (2007)
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM19169 (3-[4-(trifluoromethyl)phenoxymethyl]-5H-indeno[1,2...) Show SMILES FC(F)(F)c1ccc(OCc2cc3C(=O)c4ccccc4-c3nn2)cc1 Show InChI InChI=1S/C19H11F3N2O2/c20-19(21,22)11-5-7-13(8-6-11)26-10-12-9-16-17(24-23-12)14-3-1-2-4-15(14)18(16)25/h1-9H,10H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	37
University of Bari					Assay Description A continuous spectrophotometric assay that monitors the rate of oxidation of the nonselective MAO substrate kynuramine into 4-hydroxyquinoline was us...				J Med Chem 50: 5364-71 (2007)
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM19173 (2-phenyl-2H,3H,5H-indeno[1,2-c]pyridazine-3,5-dion...) Show SMILES O=C1c2ccccc2-c2nn(-c3ccccc3)c(=O)cc12 Show InChI InChI=1S/C17H10N2O2/c20-15-10-14-16(12-8-4-5-9-13(12)17(14)21)18-19(15)11-6-2-1-3-7-11/h1-10H	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	37
University of Bari					Assay Description A continuous spectrophotometric assay that monitors the rate of oxidation of the nonselective MAO substrate kynuramine into 4-hydroxyquinoline was us...				J Med Chem 50: 5364-71 (2007)
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM19177 (2-(3-nitrophenyl)-9H-indeno[2,1-d]pyrimidin-9-one ...) Show SMILES [O-][N+](=O)c1cccc(c1)-c1ncc2-c3ccccc3C(=O)c2n1 Show InChI InChI=1S/C17H9N3O3/c21-16-13-7-2-1-6-12(13)14-9-18-17(19-15(14)16)10-4-3-5-11(8-10)20(22)23/h1-9H	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	37
University of Bari					Assay Description A continuous spectrophotometric assay that monitors the rate of oxidation of the nonselective MAO substrate kynuramine into 4-hydroxyquinoline was us...				J Med Chem 50: 5364-71 (2007)
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM19181 (3-phenyl-4aH,9H,9aH-indeno[1,2-e][1,2,4]triazin-9-...) Show SMILES O=C1c2ccccc2-c2nc(nnc12)-c1ccccc1 Show InChI InChI=1S/C16H9N3O/c20-15-12-9-5-4-8-11(12)13-14(15)18-19-16(17-13)10-6-2-1-3-7-10/h1-9H	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	37
University of Bari					Assay Description A continuous spectrophotometric assay that monitors the rate of oxidation of the nonselective MAO substrate kynuramine into 4-hydroxyquinoline was us...				J Med Chem 50: 5364-71 (2007)
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM19182 (3-(3-aminophenyl)-4aH,9H,9aH-indeno[1,2-e][1,2,4]t...) Show SMILES Nc1cccc(c1)-c1nnc2C(=O)c3ccccc3-c2n1 Show InChI InChI=1S/C16H10N4O/c17-10-5-3-4-9(8-10)16-18-13-11-6-1-2-7-12(11)15(21)14(13)19-20-16/h1-8H,17H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	37
University of Bari					Assay Description A continuous spectrophotometric assay that monitors the rate of oxidation of the nonselective MAO substrate kynuramine into 4-hydroxyquinoline was us...				J Med Chem 50: 5364-71 (2007)
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM19183 (3-(3-nitrophenyl)-4aH,9H,9aH-indeno[1,2-e][1,2,4]t...) Show SMILES [O-][N+](=O)c1cccc(c1)-c1nnc2C(=O)c3ccccc3-c2n1 Show InChI InChI=1S/C16H8N4O3/c21-15-12-7-2-1-6-11(12)13-14(15)18-19-16(17-13)9-4-3-5-10(8-9)20(22)23/h1-8H	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	37
University of Bari					Assay Description A continuous spectrophotometric assay that monitors the rate of oxidation of the nonselective MAO substrate kynuramine into 4-hydroxyquinoline was us...				J Med Chem 50: 5364-71 (2007)
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM19184 (3-(3-nitrophenyl)-4aH,5H,9bH-indeno[2,1-e][1,2,4]t...) Show SMILES [O-][N+](=O)c1cccc(c1)-c1nnc2-c3ccccc3C(=O)c2n1 Show InChI InChI=1S/C16H8N4O3/c21-15-12-7-2-1-6-11(12)13-14(15)17-16(19-18-13)9-4-3-5-10(8-9)20(22)23/h1-8H	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	37
University of Bari					Assay Description A continuous spectrophotometric assay that monitors the rate of oxidation of the nonselective MAO substrate kynuramine into 4-hydroxyquinoline was us...				J Med Chem 50: 5364-71 (2007)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29137 (substituted chalcone, 5a) Show SMILES CC(C)=CCOc1ccc(C(=O)\C=C\c2ccccc2)c(O)c1 Show InChI InChI=1S/C20H20O3/c1-15(2)12-13-23-17-9-10-18(20(22)14-17)19(21)11-8-16-6-4-3-5-7-16/h3-12,14,22H,13H2,1-2H3/b11-8+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 2818-24 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29138 (substituted chalcone, 5b) Show SMILES CC(C)=CCOc1ccc(C(=O)\C=C\c2ccc(C)cc2)c(O)c1 Show InChI InChI=1S/C21H22O3/c1-15(2)12-13-24-18-9-10-19(21(23)14-18)20(22)11-8-17-6-4-16(3)5-7-17/h4-12,14,23H,13H2,1-3H3/b11-8+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 2818-24 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29149 (substituted chalcone, 5c) Show SMILES COc1ccc(\C=C\C(=O)c2ccc(OCC=C(C)C)cc2O)cc1 Show InChI InChI=1S/C21H22O4/c1-15(2)12-13-25-18-9-10-19(21(23)14-18)20(22)11-6-16-4-7-17(24-3)8-5-16/h4-12,14,23H,13H2,1-3H3/b11-6+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 2818-24 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29150 (substituted chalcone, 5d) Show SMILES CC(C)=CCOc1ccc(C(=O)\C=C\c2ccc(OCc3ccccc3)cc2)c(O)c1 Show InChI InChI=1S/C27H26O4/c1-20(2)16-17-30-24-13-14-25(27(29)18-24)26(28)15-10-21-8-11-23(12-9-21)31-19-22-6-4-3-5-7-22/h3-16,18,29H,17,19H2,1-2H3/b15-10+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 2818-24 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29139 (substituted chalcone, 5e) Show SMILES CC(C)=CCOc1ccc(C(=O)\C=C\c2ccc(Cl)cc2)c(O)c1 Show InChI InChI=1S/C20H19ClO3/c1-14(2)11-12-24-17-8-9-18(20(23)13-17)19(22)10-5-15-3-6-16(21)7-4-15/h3-11,13,23H,12H2,1-2H3/b10-5+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 2818-24 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29151 (substituted chalcone, 5f) Show SMILES Clc1ccc(\C=C\C(=O)c2ccc(OCc3ccccc3)cc2)cc1 Show InChI InChI=1S/C22H17ClO2/c23-20-11-6-17(7-12-20)8-15-22(24)19-9-13-21(14-10-19)25-16-18-4-2-1-3-5-18/h1-15H,16H2/b15-8+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 2818-24 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29140 (substituted chalcone, 5g) Show SMILES COc1ccc(cc1)C(=O)\C=C\c1ccc(Cl)cc1 Show InChI InChI=1S/C16H13ClO2/c1-19-15-9-5-13(6-10-15)16(18)11-4-12-2-7-14(17)8-3-12/h2-11H,1H3/b11-4+	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 2818-24 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29141 (substituted chalcone, 5h) Show SMILES COc1ccc(cc1)C(=O)\C=C\c1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C23H20O3/c1-25-21-14-10-20(11-15-21)23(24)16-9-18-7-12-22(13-8-18)26-17-19-5-3-2-4-6-19/h2-16H,17H2,1H3/b16-9+	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 2818-24 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29142 (substituted chalcone, 5i) Show SMILES COc1ccc(C(=O)\C=C\c2ccc(Cl)cc2)c(O)c1 Show InChI InChI=1S/C16H13ClO3/c1-20-13-7-8-14(16(19)10-13)15(18)9-4-11-2-5-12(17)6-3-11/h2-10,19H,1H3/b9-4+	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 2818-24 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29143 (CHEMBL7976 | Chalcone 1 | Chalcone, 13 | cid_63776...) Show SMILES O=C(\C=C\c1ccccc1)c1ccccc1 Show InChI InChI=1S/C15H12O/c16-15(14-9-5-2-6-10-14)12-11-13-7-3-1-4-8-13/h1-12H/b12-11+	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 2818-24 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29144 (substituted chalcone, 5k) Show SMILES Oc1ccccc1C(=O)\C=C\c1ccc(Cl)cc1 Show InChI InChI=1S/C15H11ClO2/c16-12-8-5-11(6-9-12)7-10-15(18)13-3-1-2-4-14(13)17/h1-10,17H/b10-7+	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 2818-24 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29145 (substituted chalcone, 5l) Show SMILES Oc1ccc(cc1)C(=O)\C=C\c1ccc(Cl)cc1 Show InChI InChI=1S/C15H11ClO2/c16-13-6-1-11(2-7-13)3-10-15(18)12-4-8-14(17)9-5-12/h1-10,17H/b10-3+	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 2818-24 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29146 (substituted chalcone, 5n) Show SMILES Oc1cc(F)ccc1C(=O)\C=C\c1ccc(Cl)cc1 Show InChI InChI=1S/C15H10ClFO2/c16-11-4-1-10(2-5-11)3-8-14(18)13-7-6-12(17)9-15(13)19/h1-9,19H/b8-3+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 2818-24 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29147 (substituted chalcone, 5o) Show SMILES Fc1ccc(cc1)C(=O)\C=C\c1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C22H17FO2/c23-20-11-9-19(10-12-20)22(24)15-8-17-6-13-21(14-7-17)25-16-18-4-2-1-3-5-18/h1-15H,16H2/b15-8+	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 2818-24 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29148 (substituted chalcone, 5p) Show SMILES CS(=O)(=O)c1ccc(cc1)C(=O)\C=C\c1ccc(Cl)cc1 Show InChI InChI=1S/C16H13ClO3S/c1-21(19,20)15-9-5-13(6-10-15)16(18)11-4-12-2-7-14(17)8-3-12/h2-11H,1H3/b11-4+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 2818-24 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29152 (3-carboxamido coumarin, 1) Show SMILES O=C(NC1CCCCC1)c1cc2ccccc2oc1=O Show InChI InChI=1S/C16H17NO3/c18-15(17-12-7-2-1-3-8-12)13-10-11-6-4-5-9-14(11)20-16(13)19/h4-6,9-10,12H,1-3,7-8H2,(H,17,18)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	37
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 1935-42 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29153 (3-carboxamido coumarin, 2) Show SMILES CC(C)NC(=O)c1cc2ccccc2oc1=O Show InChI InChI=1S/C13H13NO3/c1-8(2)14-12(15)10-7-9-5-3-4-6-11(9)17-13(10)16/h3-8H,1-2H3,(H,14,15)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	37
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 1935-42 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29154 (3-carboxamido coumarin, 3) Show SMILES CC(C)CNC(=O)c1cc2ccccc2oc1=O Show InChI InChI=1S/C14H15NO3/c1-9(2)8-15-13(16)11-7-10-5-3-4-6-12(10)18-14(11)17/h3-7,9H,8H2,1-2H3,(H,15,16)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	37
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 1935-42 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29155 (3-carboxamido coumarin, 4) Show SMILES O=C(NCC#C)c1cc2ccccc2oc1=O Show InChI InChI=1S/C13H9NO3/c1-2-7-14-12(15)10-8-9-5-3-4-6-11(9)17-13(10)16/h1,3-6,8H,7H2,(H,14,15)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	37
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 1935-42 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29156 (3-carboxamido coumarin, 5) Show SMILES NCCNC(=O)c1cc2ccccc2oc1=O Show InChI InChI=1S/C12H12N2O3/c13-5-6-14-11(15)9-7-8-3-1-2-4-10(8)17-12(9)16/h1-4,7H,5-6,13H2,(H,14,15)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	37
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 1935-42 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29157 (3-carboxamido coumarin, 7) Show SMILES O=C(Nc1ccccc1Cc1ccccc1)c1cc2ccccc2oc1=O Show InChI InChI=1S/C23H17NO3/c25-22(19-15-18-11-5-7-13-21(18)27-23(19)26)24-20-12-6-4-10-17(20)14-16-8-2-1-3-9-16/h1-13,15H,14H2,(H,24,25)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	37
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 1935-42 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29159 (3-carboxamido coumarin, 9) Show SMILES COc1cccc(NC(=O)c2cc3ccccc3oc2=O)c1 Show InChI InChI=1S/C17H13NO4/c1-21-13-7-4-6-12(10-13)18-16(19)14-9-11-5-2-3-8-15(11)22-17(14)20/h2-10H,1H3,(H,18,19)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	37
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 1935-42 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29160 (3-carboxamido coumarin, 10) Show SMILES Fc1cccc(NC(=O)c2cc3ccccc3oc2=O)c1 Show InChI InChI=1S/C16H10FNO3/c17-11-5-3-6-12(9-11)18-15(19)13-8-10-4-1-2-7-14(10)21-16(13)20/h1-9H,(H,18,19)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	37
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 1935-42 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29161 (3-carboxamido coumarin, 11) Show SMILES FC(F)(F)c1cccc(NC(=O)c2cc3ccccc3oc2=O)c1 Show InChI InChI=1S/C17H10F3NO3/c18-17(19,20)11-5-3-6-12(9-11)21-15(22)13-8-10-4-1-2-7-14(10)24-16(13)23/h1-9H,(H,21,22)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	37
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 1935-42 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29166 (3-carboxamido coumarin, 16) Show SMILES COc1ccc(NC(=O)c2cc3ccccc3oc2=O)cc1 Show InChI InChI=1S/C17H13NO4/c1-21-13-8-6-12(7-9-13)18-16(19)14-10-11-4-2-3-5-15(11)22-17(14)20/h2-10H,1H3,(H,18,19)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	37
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 1935-42 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29172 (3-carboxamido coumarin, 22) Show SMILES Oc1ccc(NC(=O)c2cc3ccccc3oc2=O)cc1 Show InChI InChI=1S/C16H11NO4/c18-12-7-5-11(6-8-12)17-15(19)13-9-10-3-1-2-4-14(10)21-16(13)20/h1-9,18H,(H,17,19)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	37
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 1935-42 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29173 (3-carboxamido coumarin, 23) Show SMILES Cc1cccc(Cl)c1NC(=O)c1cc2ccccc2oc1=O Show InChI InChI=1S/C17H12ClNO3/c1-10-5-4-7-13(18)15(10)19-16(20)12-9-11-6-2-3-8-14(11)22-17(12)21/h2-9H,1H3,(H,19,20)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	37
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 1935-42 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29183 (3-carboxamido coumarin, 33) Show SMILES Fc1c(F)c(F)c(NC(=O)c2cc3ccccc3oc2=O)c(F)c1F Show InChI InChI=1S/C16H6F5NO3/c17-9-10(18)12(20)14(13(21)11(9)19)22-15(23)7-5-6-3-1-2-4-8(6)25-16(7)24/h1-5H,(H,22,23)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 1935-42 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29186 (3-carboxamido coumarin, 36) Show SMILES O=C(NCc1ccccc1)c1cc2ccccc2oc1=O Show InChI InChI=1S/C17H13NO3/c19-16(18-11-12-6-2-1-3-7-12)14-10-13-8-4-5-9-15(13)21-17(14)20/h1-10H,11H2,(H,18,19)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 1935-42 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29187 (3-carboxamido coumarin, 37) Show SMILES O=C(NCCc1ccccc1)c1cc2ccccc2oc1=O Show InChI InChI=1S/C18H15NO3/c20-17(19-11-10-13-6-2-1-3-7-13)15-12-14-8-4-5-9-16(14)22-18(15)21/h1-9,12H,10-11H2,(H,19,20)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 1935-42 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29188 (3-carboxamido coumarin, 38) Show SMILES CN(C(=O)c1cc2ccccc2oc1=O)c1ccccc1 Show InChI InChI=1S/C17H13NO3/c1-18(13-8-3-2-4-9-13)16(19)14-11-12-7-5-6-10-15(12)21-17(14)20/h2-11H,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 1935-42 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29189 (3-carboxamido coumarin, 39) Show SMILES CN(Cc1ccccc1)C(=O)c1cc2ccccc2oc1=O Show InChI InChI=1S/C18H15NO3/c1-19(12-13-7-3-2-4-8-13)17(20)15-11-14-9-5-6-10-16(14)22-18(15)21/h2-11H,12H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 1935-42 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29190 (3-carboxamido coumarin, 40) Show SMILES O=C(N(c1ccccc1)c1ccccc1)c1cc2ccccc2oc1=O Show InChI InChI=1S/C22H15NO3/c24-21(19-15-16-9-7-8-14-20(16)26-22(19)25)23(17-10-3-1-4-11-17)18-12-5-2-6-13-18/h1-15H	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 1935-42 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29191 (3-carboxamido coumarin, 41) Show SMILES O=C(NC1CCCCC1)c1cc2ccc(OCc3ccccc3)cc2oc1=O Show InChI InChI=1S/C23H23NO4/c25-22(24-18-9-5-2-6-10-18)20-13-17-11-12-19(14-21(17)28-23(20)26)27-15-16-7-3-1-4-8-16/h1,3-4,7-8,11-14,18H,2,5-6,9-10,15H2,(H,24,25)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 1935-42 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29198 (3-carboxamido coumarin, 48) Show SMILES COc1ccc(NC(=O)c2cc3ccc(OCc4ccccc4)cc3oc2=O)cc1OC Show InChI InChI=1S/C25H21NO6/c1-29-21-11-9-18(13-23(21)30-2)26-24(27)20-12-17-8-10-19(14-22(17)32-25(20)28)31-15-16-6-4-3-5-7-16/h3-14H,15H2,1-2H3,(H,26,27)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 1935-42 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29200 (3-carboxamido coumarin, 50) Show SMILES O=C(NCc1ccccc1)c1cc2ccc(OCc3ccccc3)cc2oc1=O Show InChI InChI=1S/C24H19NO4/c26-23(25-15-17-7-3-1-4-8-17)21-13-19-11-12-20(14-22(19)29-24(21)27)28-16-18-9-5-2-6-10-18/h1-14H,15-16H2,(H,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 1935-42 (2009)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29207 (3-carboxamido coumarin, 57) Show SMILES CC(C)c1ccc(NC(=O)c2cc3ccc(OCc4ccc(F)cc4)cc3oc2=O)cc1 Show InChI InChI=1S/C26H22FNO4/c1-16(2)18-5-10-21(11-6-18)28-25(29)23-13-19-7-12-22(14-24(19)32-26(23)30)31-15-17-3-8-20(27)9-4-17/h3-14,16H,15H2,1-2H3,(H,28,29)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 1935-42 (2009)
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM19166 (3-phenyl-5H-pyridazino[4,3-b]indole | Aza-heterocy...) Show SMILES c1ccc(cc1)-c1cc2[nH]c3ccccc3c2nn1 Show InChI InChI=1S/C16H11N3/c1-2-6-11(7-3-1)14-10-15-16(19-18-14)12-8-4-5-9-13(12)17-15/h1-10,17H	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	37
University of Bari					Assay Description A continuous spectrophotometric assay that monitors the rate of oxidation of the nonselective MAO substrate kynuramine into 4-hydroxyquinoline was us...				J Med Chem 50: 5364-71 (2007)
					More data for this Ligand-Target Pair