Target (Institution) | Ligand | Target Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Chitinase Mutant (T138A) (Aspergillus fumigatus) | BDBM10853![]() ((2R,5S,8S,11S,15S)-8-benzyl-2,7-dimethyl-5-[3-({[(...) | PDB MMDB B.MOAD GoogleScholar AffyNet ![]() | MMDB PC cid PC sid UniChem Similars AffyNet ![]() | MMDB Article PubMed | n/a | n/a | n/a | 1.21E+3 | n/a | n/a | n/a | n/a | n/a |
University of Dundee | Assay Description Fluorescence measurements were carried out with a Varian Cary Eclipse fluorescence spectrophotometer. Emission spectra were recorded from 330-360 nm ... | Chem Biol 12: 65-76 (2005) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitinase Mutant (T138A) (Aspergillus fumigatus) | BDBM10854![]() (4-[(1S,4R,10S,13S,16S,18R)-10-{3-[(acetamidomethan...) | PDB MMDB B.MOAD GoogleScholar AffyNet ![]() | CHEMBL MMDB PC cid PC sid UniChem AffyNet ![]() | MMDB Article PubMed | n/a | n/a | n/a | 3.04E+3 | n/a | n/a | n/a | n/a | n/a |
University of Dundee | Assay Description Fluorescence measurements were carried out with a Varian Cary Eclipse fluorescence spectrophotometer. Emission spectra were recorded from 330-360 nm ... | Chem Biol 12: 65-76 (2005) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitinase Mutant (T138A) (Aspergillus fumigatus) | BDBM10850![]() (1-(5-Oxohexyl)theobromine (pentoxifylline) | 3,7-d...) | PDB MMDB B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars AffyNet ![]() | MMDB PDB Article PubMed | n/a | n/a | n/a | 6.50E+4 | n/a | n/a | n/a | n/a | n/a |
University of Dundee | Assay Description Fluorescence measurements were carried out with a Varian Cary Eclipse fluorescence spectrophotometer. Emission spectra were recorded from 330-360 nm ... | Chem Biol 12: 973-80 (2005) | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |