Found 103 hits of affinity data for UniProtKB/TrEMBL: P35218Target (Institution) | Ligand | Target Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | pH | Temp °C |
Carbonic Anhydrase VA
Homo sapiens (human) | sulfonamide deriv., 7a
 | GoogleScholar KEGG UniProtKB/SwissProt
| CSLS PC cid PC sid
| PubMed
| 6.700 | -46.65 | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University
|
Bioorg Med Chem. 17: 4894-9 (2009)
|
Carbonic Anhydrase VA
Homo sapiens (human) | sulfonamide deriv., 7g
 | GoogleScholar KEGG UniProtKB/SwissProt
| PC cid PC sid
| PubMed
| 6.800 | -46.61 | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University
|
Bioorg Med Chem. 17: 4894-9 (2009)
|
Carbonic Anhydrase VA
Homo sapiens (human) | sulfonamide deriv., 5b
 | GoogleScholar KEGG UniProtKB/SwissProt
| PC cid PC sid
| PubMed
| 6.900 | -46.58 | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University
|
Bioorg Med Chem. 17: 4894-9 (2009)
|
Carbonic Anhydrase VA
Homo sapiens (human) | sulfonamide deriv., 7f
 | GoogleScholar KEGG UniProtKB/SwissProt
| PC cid PC sid
| PubMed
| 7.100 | -46.51 | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University
|
Bioorg Med Chem. 17: 4894-9 (2009)
|
Carbonic Anhydrase VA
Homo sapiens (human) | sulfonamide deriv., 5a
 | GoogleScholar KEGG UniProtKB/SwissProt
| CSLS PC cid PC sid
| PubMed
| 7.200 | -46.47 | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University
|
Bioorg Med Chem. 17: 4894-9 (2009)
|
Carbonic Anhydrase VA
Homo sapiens (human) | sulfonamide deriv., 7h
 | GoogleScholar KEGG UniProtKB/SwissProt
| PC cid PC sid
| PubMed
| 7.300 | -46.44 | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University
|
Bioorg Med Chem. 17: 4894-9 (2009)
|
Carbonic Anhydrase VA
Homo sapiens (human) | sulfonamide deriv., 5d
 | GoogleScholar KEGG UniProtKB/SwissProt
| PC cid PC sid
| PubMed
| 7.500 | -46.37 | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University
|
Bioorg Med Chem. 17: 4894-9 (2009)
|
Carbonic Anhydrase VA
Homo sapiens (human) | sulfonamide deriv., 6
 | GoogleScholar KEGG UniProtKB/SwissProt
| PC cid PC sid
| PubMed
| 7.600 | -46.34 | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University
|
Bioorg Med Chem. 17: 4894-9 (2009)
|
Carbonic Anhydrase VA
Homo sapiens (human) | sulfonamide deriv., 7i
 | GoogleScholar KEGG UniProtKB/SwissProt
| PC cid PC sid
| PubMed
| 7.600 | -46.34 | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University
|
Bioorg Med Chem. 17: 4894-9 (2009)
|
Carbonic Anhydrase VA
Homo sapiens (human) | sulfonamide deriv., 5c
 | GoogleScholar KEGG UniProtKB/SwissProt
| PC cid PC sid
| PubMed
| 7.700 | -46.30 | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University
|
Bioorg Med Chem. 17: 4894-9 (2009)
|
Carbonic Anhydrase VA
Homo sapiens (human) | sulfonamide deriv., 7c
 | GoogleScholar KEGG UniProtKB/SwissProt
| CSLS PC cid PC sid
| PubMed
| 8.100 | -46.18 | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University
|
Bioorg Med Chem. 17: 4894-9 (2009)
|
Carbonic Anhydrase VA
Homo sapiens (human) | sulfonamide deriv., 7e
 | GoogleScholar KEGG UniProtKB/SwissProt
| CSLS PC cid PC sid
| PubMed
| 8.200 | -46.15 | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University
|
Bioorg Med Chem. 17: 4894-9 (2009)
|
Carbonic Anhydrase VA
Homo sapiens (human) | sulfonamide deriv., 7d
 | GoogleScholar KEGG UniProtKB/SwissProt
| PC cid PC sid
| PubMed
| 8.300 | -46.12 | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University
|
Bioorg Med Chem. 17: 4894-9 (2009)
|
Carbonic Anhydrase VA
Homo sapiens (human) | sulfonamide deriv., 8
 | GoogleScholar KEGG UniProtKB/SwissProt
| PC cid PC sid
| PubMed
| 8.400 | -46.09 | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University
|
Bioorg Med Chem. 17: 4894-9 (2009)
|
Carbonic Anhydrase VA
Homo sapiens (human) | sulfonamide deriv., 7b
 | GoogleScholar KEGG UniProtKB/SwissProt
| CSLS PC cid PC sid
| PubMed
| 8.600 | -46.03 | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University
|
Bioorg Med Chem. 17: 4894-9 (2009)
|
Carbonic Anhydrase VA
Homo sapiens (human) | sulfonamide deriv., 5e
 | GoogleScholar KEGG UniProtKB/SwissProt
| CSLS PC cid PC sid
| PubMed
| 9.100 | -45.89 | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University
|
Bioorg Med Chem. 17: 4894-9 (2009)
|
Carbonic Anhydrase VA
Homo sapiens (human) | sulfonamide deriv., 5f
 | GoogleScholar KEGG UniProtKB/SwissProt
| CSLS PC cid PC sid
| PubMed
| 10.20 | -45.61 | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University
|
Bioorg Med Chem. 17: 4894-9 (2009)
|
Carbonic Anhydrase VA
Homo sapiens (human) | Ethoxzolamide (EZA)
 (6-ethoxy-1,3-benzothiazole-2-sulfonamide | sulfona...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| CHEBI CSLS DrugBank MMDB PC cid PC sid PDB
| PubMed
| 25.00 | -42.95 | n/a | n/a | n/a | 7.5 | 22 |
Universite Montpellier II
|
J Med Chem. 49: 7024-31 (2006)
|
Carbonic Anhydrase VA
Homo sapiens (human) | Ethoxzolamide (EZA)
 (6-ethoxy-1,3-benzothiazole-2-sulfonamide | sulfona...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| CHEBI CSLS DrugBank MMDB PC cid PC sid PDB
| PubMed
| 25.00 | -43.39 | n/a | n/a | n/a | 7.5 | 25 |
Kochi Medical School
|
J Med Chem. 48: 7860-6 (2005)
|
Carbonic Anhydrase VA
Homo sapiens (human) | Topiramate Sulfamide Analogue 8
 (Compound 8 | amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tet...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| B.MOAD CHEBI CSLS MMDB PC cid PC sid PDB
| PubMed
| 32.00 | -42.34 | n/a | n/a | n/a | 7.5 | 22 |
Universite Montpellier II
|
J Med Chem. 49: 7024-31 (2006)
|
Carbonic Anhydrase VA
Homo sapiens (human) | aromatic/heteroaromatic sulfonamide 15
 (2-N-(4-aminobenzene)-1,3,4-thiadiazole-2,5-disulfo...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| CHEBI CSLS PC cid PC sid
| PubMed
| 34.00 | -42.62 | n/a | n/a | n/a | 7.5 | 25 |
Kochi Medical School
|
J Med Chem. 48: 7860-6 (2005)
|
Carbonic Anhydrase VA
Homo sapiens (human) | Benzolamide (BZA)
 (2-N-benzene-1,3,4-thiadiazole-2,5-disulfonamide) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| CHEBI CSLS MMDB PC cid PC sid PDB
| PubMed
| 37.00 | -42.41 | n/a | n/a | n/a | 7.5 | 25 |
Kochi Medical School
|
J Med Chem. 48: 7860-6 (2005)
|
Carbonic Anhydrase VA
Homo sapiens (human) | Dorzolamide (DZA)
 ((2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| B.MOAD CHEBI CSLS KEGG MMDB PC cid PC sid PDB
| PubMed
| 42.00 | -42.10 | n/a | n/a | n/a | 7.5 | 25 |
Kochi Medical School
|
J Med Chem. 48: 7860-6 (2005)
|
Carbonic Anhydrase VA
Homo sapiens (human) | sulfonamide 5
 ((2R,4R)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| CHEBI CSLS PC cid PC sid
| PubMed
| 42.00 | -41.68 | n/a | n/a | n/a | 7.5 | 22 |
Universite Montpellier II
|
J Med Chem. 49: 7024-31 (2006)
|
Carbonic Anhydrase VA
Homo sapiens (human) | Dorzolamide (DZA)
 ((2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| B.MOAD CHEBI CSLS KEGG MMDB PC cid PC sid PDB
| PubMed
| 42.00 | -41.82 | n/a | n/a | n/a | 7.5 | 23 |
CNR
|
J Med Chem. 52: 5990-8 (2009)
|
Carbonic Anhydrase VA
Homo sapiens (human) | aromatic/heteroaromatic sulfonamide 20
 (5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| CHEBI CSLS MMDB PC cid PC sid PDB
| PubMed
| 43.00 | -42.04 | n/a | n/a | n/a | 7.5 | 25 |
Kochi Medical School
|
J Med Chem. 48: 7860-6 (2005)
|
Carbonic Anhydrase VA
Homo sapiens (human) | sulfonamide 6
 ((4S)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| CHEBI CSLS PC cid PC sid
| PubMed
| 50.00 | -41.25 | n/a | n/a | n/a | 7.5 | 22 |
Universite Montpellier II
|
J Med Chem. 49: 7024-31 (2006)
|
Carbonic Anhydrase VA
Homo sapiens (human) | Brinzolamide (BRZ)
 ((4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| CHEBI CSLS DrugBank KEGG PC cid PC sid PDB
| PubMed
| 50.00 | -41.67 | n/a | n/a | n/a | 7.5 | 25 |
Kochi Medical School
|
J Med Chem. 48: 7860-6 (2005)
|
Carbonic Anhydrase VA
Homo sapiens (human) | aromatic/heteroaromatic sulfonamide 19
 (6-hydroxy-1,3-benzothiazole-2-sulfonamide) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| CHEBI CSLS MMDB PC cid PC sid PDB
| PubMed
| 54.00 | -41.48 | n/a | n/a | n/a | 7.5 | 25 |
Kochi Medical School
|
J Med Chem. 48: 7860-6 (2005)
|
Carbonic Anhydrase VA
Homo sapiens (human) | Acetazolamide (AAZ)
 (AZA | N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetami...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| B.MOAD CHEBI CSLS DrugBank KEGG MMDB PC cid PC sid PDB
| PubMed
| 63.00 | -41.09 | n/a | n/a | n/a | 7.4 | 25 |
Universita degli Studi di Firenze
|
Bioorg Med Chem Lett. 18: 4282-6 (2008)
|
Carbonic Anhydrase VA
Homo sapiens (human) | Topiramate (TPM)
 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| CHEBI CSLS DrugBank KEGG MMDB PC cid PC sid PDB
| PubMed
| 63.00 | -41.09 | n/a | n/a | n/a | 7.5 | 25 |
Kochi Medical School
|
J Med Chem. 48: 7860-6 (2005)
|
Carbonic Anhydrase VA
Homo sapiens (human) | Topiramate (TPM)
 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| CHEBI CSLS DrugBank KEGG MMDB PC cid PC sid PDB
| PubMed
| 63.00 | -40.68 | n/a | n/a | n/a | 7.5 | 22 |
Universite Montpellier II
|
J Med Chem. 49: 7024-31 (2006)
|
Carbonic Anhydrase VA
Homo sapiens (human) | Acetazolamide (AAZ)
 (AZA | N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetami...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| B.MOAD CHEBI CSLS DrugBank KEGG MMDB PC cid PC sid PDB
| PubMed
| 63.00 | -40.68 | n/a | n/a | n/a | 7.5 | 22 |
Universite Montpellier II
|
J Med Chem. 49: 7024-31 (2006)
|
Carbonic Anhydrase VA
Homo sapiens (human) | Acetazolamide (AAZ)
 (AZA | N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetami...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| B.MOAD CHEBI CSLS DrugBank KEGG MMDB PC cid PC sid PDB
| PubMed
| 63.00 | -41.09 | n/a | n/a | n/a | 7.5 | 25 |
Kochi Medical School
|
J Med Chem. 48: 7860-6 (2005)
|
Carbonic Anhydrase VA
Homo sapiens (human) | Topiramate (TPM)
 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| CHEBI CSLS DrugBank KEGG MMDB PC cid PC sid PDB
| PubMed
| 63.00 | -41.09 | n/a | n/a | n/a | 7.4 | 25 |
Universita degli Studi di Firenze
|
Bioorg Med Chem Lett. 18: 4282-6 (2008)
|
Carbonic Anhydrase VA
Homo sapiens (human) | Acetazolamide (AAZ)
 (AZA | N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetami...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| B.MOAD CHEBI CSLS DrugBank KEGG MMDB PC cid PC sid PDB
| PubMed
| 63.00 | -40.82 | n/a | n/a | n/a | 7.5 | 23 |
CNR
|
J Med Chem. 52: 5990-8 (2009)
|
Carbonic Anhydrase VA
Homo sapiens (human) | Methazolamide (MZA)
 (N-[(2Z)-3-methyl-5-sulfamoyl-2,3-dihydro-1,3,4-thi...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| CHEBI CSLS DrugBank PC cid PC sid
| PubMed
| 65.00 | -41.02 | n/a | n/a | n/a | 7.5 | 25 |
Kochi Medical School
|
J Med Chem. 48: 7860-6 (2005)
|
Carbonic Anhydrase VA
Homo sapiens (human) | Methazolamide (MZA)
 (N-[(2Z)-3-methyl-5-sulfamoyl-2,3-dihydro-1,3,4-thi...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| CHEBI CSLS DrugBank PC cid PC sid
| PubMed
| 65.00 | -40.60 | n/a | n/a | n/a | 7.5 | 22 |
Universite Montpellier II
|
J Med Chem. 49: 7024-31 (2006)
|
Carbonic Anhydrase VA
Homo sapiens (human) | Indisulam (IND)
 (1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| CHEBI CSLS DrugBank PC cid PC sid
| PubMed
| 79.00 | -40.53 | n/a | n/a | n/a | 7.5 | 25 |
Kochi Medical School
|
J Med Chem. 48: 7860-6 (2005)
|
Carbonic Anhydrase VA
Homo sapiens (human) | aromatic/heteroaromatic sulfonamide 17
 (4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| CHEBI CSLS PC cid PC sid
| PubMed
| 121.0 | -39.48 | n/a | n/a | n/a | 7.5 | 25 |
Kochi Medical School
|
J Med Chem. 48: 7860-6 (2005)
|
Carbonic Anhydrase VA
Homo sapiens (human) | Sulpiride (SLP)
 (2-methoxy-N-[(1-methylpyrrolidin-2-yl)methyl]-5-su...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| CHEBI CSLS PC cid PC sid
| PubMed
| 174.0 | -38.58 | n/a | n/a | n/a | 7.5 | 25 |
Kochi Medical School
|
J Med Chem. 48: 7860-6 (2005)
|
Carbonic Anhydrase VA
Homo sapiens (human) | aromatic/heteroaromatic sulfonamide 16
 (4-amino-N-[(4-sulfamoylphenyl)methyl]benzene-1-sul...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| CHEBI CSLS PC cid PC sid
| PubMed
| 176.0 | -38.55 | n/a | n/a | n/a | 7.5 | 25 |
Kochi Medical School
|
J Med Chem. 48: 7860-6 (2005)
|
Carbonic Anhydrase VA
Homo sapiens (human) | Furosemide
 (4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbe...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| CHEBI CSLS DrugBank PC cid PC sid PDB
| PubMed
| 499.0 | -35.96 | n/a | n/a | n/a | 7.4 | 25 |
Universita degli Studi di Firenze
|
Bioorg Med Chem Lett. 18: 2567-73 (2008)
|
Carbonic Anhydrase VA
Homo sapiens (human) | indole sulfonamide, 8l
 (3-(4-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| PC cid PC sid
| PubMed
| 619.0 | -35.43 | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University
|
Bioorg Med Chem. 16: 9113-20 (2008)
|
Carbonic Anhydrase VA
Homo sapiens (human) | Dichlorophenamide (DCP)
 (4,5-dichlorobenzene-1,3-disulfonamide | sulfonamid...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| B.MOAD CHEBI CSLS DrugBank KEGG PC cid PC sid PDB
| PubMed
| 630.0 | -35.03 | n/a | n/a | n/a | 7.5 | 22 |
Universite Montpellier II
|
J Med Chem. 49: 7024-31 (2006)
|
Carbonic Anhydrase VA
Homo sapiens (human) | Dichlorophenamide (DCP)
 (4,5-dichlorobenzene-1,3-disulfonamide | sulfonamid...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| B.MOAD CHEBI CSLS DrugBank KEGG PC cid PC sid PDB
| PubMed
| 630.0 | -35.39 | n/a | n/a | n/a | 7.5 | 25 |
Kochi Medical School
|
J Med Chem. 48: 7860-6 (2005)
|
Carbonic Anhydrase VA
Homo sapiens (human) | indole sulfonamide, 8i
 (3-(4-chlorophenyl)-2-(hydrazinecarbonyl)-1H-indole...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| PC cid PC sid
| PubMed
| 658.0 | -35.28 | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University
|
Bioorg Med Chem. 16: 9113-20 (2008)
|
Carbonic Anhydrase VA
Homo sapiens (human) | EMD 486019
 ([2-(cycloheptylmethyl)-1,1-dioxo-1$l^{6}-benzothio...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| CSLS PC cid PC sid PDB
| PubMed
| 682.0 | -35.19 | n/a | n/a | n/a | 7.4 | 25 |
Universita degli Studi di Firenze
|
Bioorg Med Chem Lett. 18: 4282-6 (2008)
|
Carbonic Anhydrase VA
Homo sapiens (human) | Bumetanide
 (3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid |...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| CSLS DrugBank PC cid PC sid
| PubMed
| 700.0 | -35.13 | n/a | n/a | n/a | 7.4 | 25 |
Universita degli Studi di Firenze
|
Bioorg Med Chem Lett. 18: 2567-73 (2008)
|
Carbonic Anhydrase VA
Homo sapiens (human) | indole sulfonamide, 8f
 (3-(4-fluorophenyl)-2-(hydrazinecarbonyl)-1H-indole...) | GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL
| PC cid PC sid
| PubMed
| 705.0 | -35.11 | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University
|
Bioorg Med Chem. 16: 9113-20 (2008)
|