Compile Data Set for Download or QSAR
(2D       Computed 3D by Vconf -m prep )

Data curated solely by BindingDB

Found 52 hits of affinity data for UniProtKB/TrEMBL: P43166

Target (Institution)	Ligand	Target Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	pH	Temp °C
Carbonic Anhydrase VII Homo sapiens (human)	Indapamide (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS DrugBank PC cid PC sid PDB	PubMed	0.2300	-55.01	n/a	n/a	n/a	7.4	25
Universita degli Studi di Firenze					Bioorg Med Chem Lett. 18: 2567-73 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	Ethoxzolamide (EZA) (6-ethoxy-1,3-benzothiazole-2-sulfonamide | sulfona...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS DrugBank MMDB PC cid PC sid PDB	PubMed	0.8000	-51.40	n/a	n/a	n/a	7.5	22
Universite Montpellier II					J Med Chem. 49: 7024-31 (2006)
Carbonic Anhydrase VII Homo sapiens (human)	Topiramate (TPM) (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS DrugBank KEGG MMDB PC cid PC sid PDB	PubMed	0.9000	-51.11	n/a	n/a	n/a	7.5	22
Universite Montpellier II					J Med Chem. 49: 7024-31 (2006)
Carbonic Anhydrase VII Homo sapiens (human)	Topiramate (TPM) (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS DrugBank KEGG MMDB PC cid PC sid PDB	PubMed	0.9000	-51.63	n/a	n/a	n/a	7.4	25
Universita degli Studi di Firenze					Bioorg Med Chem Lett. 18: 4282-6 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	Methazolamide (MZA) (N-[(2Z)-3-methyl-5-sulfamoyl-2,3-dihydro-1,3,4-thi...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS DrugBank PC cid PC sid	PubMed	2.100	-49.03	n/a	n/a	n/a	7.5	22
Universite Montpellier II					J Med Chem. 49: 7024-31 (2006)
Carbonic Anhydrase VII Homo sapiens (human)	Metolazone (7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS DrugBank PC cid PC sid	PubMed	2.100	-49.53	n/a	n/a	n/a	7.4	25
Universita degli Studi di Firenze					Bioorg Med Chem Lett. 18: 2567-73 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	Acetazolamide (AAZ) (AZA | N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetami...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	B.MOAD CHEBI CSLS DrugBank KEGG MMDB PC cid PC sid PDB	PubMed	2.500	-49.09	n/a	n/a	n/a	7.4	25
Universita degli Studi di Firenze					Bioorg Med Chem Lett. 18: 4282-6 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	Acetazolamide (AAZ) (AZA | N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetami...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	B.MOAD CHEBI CSLS DrugBank KEGG MMDB PC cid PC sid PDB	PubMed	2.500	-48.76	n/a	n/a	n/a	7.5	23
CNR					J Med Chem. 52: 5990-8 (2009)
Carbonic Anhydrase VII Homo sapiens (human)	Acetazolamide (AAZ) (AZA | N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetami...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	B.MOAD CHEBI CSLS DrugBank KEGG MMDB PC cid PC sid PDB	PubMed	2.500	-48.60	n/a	n/a	n/a	7.5	22
Universite Montpellier II					J Med Chem. 49: 7024-31 (2006)
Carbonic Anhydrase VII Homo sapiens (human)	Chlorthalidone (2-chloro-5-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindo...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS DrugBank PC cid PC sid PDB	PubMed	2.800	-48.81	n/a	n/a	n/a	7.4	25
Universita degli Studi di Firenze					Bioorg Med Chem Lett. 18: 2567-73 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	sulfonamide 6 ((4S)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS PC cid PC sid	PubMed	2.800	-48.32	n/a	n/a	n/a	7.5	22
Universite Montpellier II					J Med Chem. 49: 7024-31 (2006)
Carbonic Anhydrase VII Homo sapiens (human)	sulfonamide 5 ((2R,4R)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS PC cid PC sid	PubMed	3.500	-47.77	n/a	n/a	n/a	7.5	22
Universite Montpellier II					J Med Chem. 49: 7024-31 (2006)
Carbonic Anhydrase VII Homo sapiens (human)	Dorzolamide (DZA) ((2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	B.MOAD CHEBI CSLS KEGG MMDB PC cid PC sid PDB	PubMed	3.500	-47.94	n/a	n/a	n/a	7.5	23
CNR					J Med Chem. 52: 5990-8 (2009)
Carbonic Anhydrase VII Homo sapiens (human)	trichloromethiazide, 6 (6-chloro-3-(dichloromethyl)-1,1-dioxo-3,4-dihydro-...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS DrugBank KEGG PC cid PC sid PDB	PubMed	7.900	-45.47	n/a	n/a	n/a	7.5	20
Universita degli Studi di Firenze					Bioorg Med Chem. 17: 1214-21 (2009)
Carbonic Anhydrase VII Homo sapiens (human)	EMD 486019 ([2-(cycloheptylmethyl)-1,1-dioxo-1$l^{6}-benzothio...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid PDB	PubMed	19.00	-44.07	n/a	n/a	n/a	7.4	25
Universita degli Studi di Firenze					Bioorg Med Chem Lett. 18: 4282-6 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	667-COUMATE (6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	B.MOAD CHEBI CSLS DrugBank PC cid PC sid PDB	PubMed	23.00	-43.59	n/a	n/a	n/a	7.4	25
Universita degli Studi di Firenze					Bioorg Med Chem Lett. 18: 4282-6 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	Dichlorophenamide (DCP) (4,5-dichlorobenzene-1,3-disulfonamide | sulfonamid...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	B.MOAD CHEBI CSLS DrugBank KEGG PC cid PC sid PDB	PubMed	26.00	-42.85	n/a	n/a	n/a	7.5	22
Universite Montpellier II					J Med Chem. 49: 7024-31 (2006)
Carbonic Anhydrase VII Homo sapiens (human)	Topiramate Sulfamide Analogue 8 (Compound 8 | amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tet...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	B.MOAD CHEBI CSLS MMDB PC cid PC sid PDB	PubMed	35.00	-42.12	n/a	n/a	n/a	7.5	22
Universite Montpellier II					J Med Chem. 49: 7024-31 (2006)
Carbonic Anhydrase VII Homo sapiens (human)	indole sulfonamide, 8f (3-(4-fluorophenyl)-2-(hydrazinecarbonyl)-1H-indole...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	54.00	-41.48	n/a	n/a	n/a	7.4	25
Istanbul University					Bioorg Med Chem. 16: 9113-20 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	indole sulfonamide, 8l (3-(4-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	58.00	-41.30	n/a	n/a	n/a	7.4	25
Istanbul University					Bioorg Med Chem. 16: 9113-20 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	indole sulfonamide, 8i (3-(4-chlorophenyl)-2-(hydrazinecarbonyl)-1H-indole...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	61.00	-41.17	n/a	n/a	n/a	7.4	25
Istanbul University					Bioorg Med Chem. 16: 9113-20 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	indole sulfonamide, 8c (2-(hydrazinecarbonyl)-3-(4-methylphenyl)-1H-indole...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	62.00	-41.13	n/a	n/a	n/a	7.4	25
Istanbul University					Bioorg Med Chem. 16: 9113-20 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	Bumetanide (3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid |...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS DrugBank PC cid PC sid	PubMed	62.00	-41.13	n/a	n/a	n/a	7.4	25
Universita degli Studi di Firenze					Bioorg Med Chem Lett. 18: 2567-73 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	indole sulfonamide, 8n (2-(hydrazinecarbonyl)-3-(2,3,4,5,6-pentafluorophen...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	68.00	-40.91	n/a	n/a	n/a	7.4	25
Istanbul University					Bioorg Med Chem. 16: 9113-20 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	indole sulfonamide, 8e (3-(3-fluorophenyl)-2-(hydrazinecarbonyl)-1H-indole...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	69.00	-40.87	n/a	n/a	n/a	7.4	25
Istanbul University					Bioorg Med Chem. 16: 9113-20 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	indole sulfonamide, 8m (2-(hydrazinecarbonyl)-3-(3-methoxyphenyl)-1H-indol...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	69.00	-40.87	n/a	n/a	n/a	7.4	25
Istanbul University					Bioorg Med Chem. 16: 9113-20 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	indole sulfonamide, 8b (2-(hydrazinecarbonyl)-3-(3-methylphenyl)-1H-indole...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	69.00	-40.87	n/a	n/a	n/a	7.4	25
Istanbul University					Bioorg Med Chem. 16: 9113-20 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	indole sulfonamide, 8k (3-(3-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	72.00	-40.76	n/a	n/a	n/a	7.4	25
Istanbul University					Bioorg Med Chem. 16: 9113-20 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	indole sulfonamide, 8h (3-(3-chlorophenyl)-2-(hydrazinecarbonyl)-1H-indole...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	72.00	-40.76	n/a	n/a	n/a	7.4	25
Istanbul University					Bioorg Med Chem. 16: 9113-20 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	aliphatic sulfamate, 1	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS MMDB PC cid PC sid PDB	PubMed	76.60	-40.34	n/a	n/a	n/a	7.5	23
CNR					J Med Chem. 52: 5990-8 (2009)
Carbonic Anhydrase VII Homo sapiens (human)	bis-sulfamate, 3	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS MMDB PC cid PC sid PDB	PubMed	79.60	-40.24	n/a	n/a	n/a	7.5	23
CNR					J Med Chem. 52: 5990-8 (2009)
Carbonic Anhydrase VII Homo sapiens (human)	indole sulfonamide, 8a (2-(hydrazinecarbonyl)-3-(2-methylphenyl)-1H-indole...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	80.00	-40.50	n/a	n/a	n/a	7.4	25
Istanbul University					Bioorg Med Chem. 16: 9113-20 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	indole sulfonamide, 8g (3-(2-chlorophenyl)-2-(hydrazinecarbonyl)-1H-indole...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	82.00	-40.44	n/a	n/a	n/a	7.4	25
Istanbul University					Bioorg Med Chem. 16: 9113-20 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	indole sulfonamide, 8j (3-(2-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	83.00	-40.41	n/a	n/a	n/a	7.4	25
Istanbul University					Bioorg Med Chem. 16: 9113-20 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	indole sulfonamide, 8d (3-(2-fluorophenyl)-2-(hydrazinecarbonyl)-1H-indole...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	85.00	-40.35	n/a	n/a	n/a	7.4	25
Istanbul University					Bioorg Med Chem. 16: 9113-20 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	aliphatic sulfamate, 2	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS MMDB PC cid PC sid PDB	PubMed	88.90	-39.97	n/a	n/a	n/a	7.5	23
CNR					J Med Chem. 52: 5990-8 (2009)
Carbonic Anhydrase VII Homo sapiens (human)	indole sulfonamide, L (2-(hydrazinecarbonyl)-3-phenyl-1H-indole-5-sulfona...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI MMDB PC cid PC sid PDB	PubMed	89.00	-40.24	n/a	n/a	n/a	7.4	25
Istanbul University					Bioorg Med Chem. 16: 9113-20 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	bis-sulfamate, 4	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS MMDB PC cid PC sid PDB	PubMed	92.30	-39.88	n/a	n/a	n/a	7.5	23
CNR					J Med Chem. 52: 5990-8 (2009)
Carbonic Anhydrase VII Homo sapiens (human)	Hydroflumethiazide (1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1$l^{...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS DrugBank KEGG MMDB PC cid PC sid PDB	PubMed	433.0	-36.32	n/a	n/a	n/a	7.4	25
Universita degli Studi di Firenze					Bioorg Med Chem Lett. 18: 2567-73 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	Furosemide (4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbe...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS DrugBank PC cid PC sid PDB	PubMed	513.0	-35.90	n/a	n/a	n/a	7.4	25
Universita degli Studi di Firenze					Bioorg Med Chem Lett. 18: 2567-73 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	Hydrochlorothiazide (6-chloro-1,1-dioxo-3,4-dihydro-2H-1$l^{6},2,4-benz...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS DrugBank MMDB PC cid PC sid PDB	PubMed	5010	-30.25	n/a	n/a	n/a	7.4	25
Universita degli Studi di Firenze					Bioorg Med Chem Lett. 18: 2567-73 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	phenol derivative, 11 (N-(4-hydroxyphenyl)acetamide)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS DrugBank KEGG MMDB PC cid PC sid PDB	PubMed	9100	-28.77	n/a	n/a	n/a	7.4	25
Universita degli Studi di Firenze					Bioorg Med Chem. 16: 7424-8 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	phenol derivative, 7 (2-hydroxybenzoic acid)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS DrugBank KEGG MMDB PC cid PC sid PDB	PubMed	82100	-23.32	n/a	n/a	n/a	7.4	25
Universita degli Studi di Firenze					Bioorg Med Chem. 16: 7424-8 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	phenol derivative, 6 (3,5-difluorophenol)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	163000	-21.62	n/a	n/a	n/a	7.4	25
Universita degli Studi di Firenze					Bioorg Med Chem. 16: 7424-8 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	phenol derivative, 5 (2,5-difluorophenol)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	554000	-18.58	n/a	n/a	n/a	7.4	25
Universita degli Studi di Firenze					Bioorg Med Chem. 16: 7424-8 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	phenol derivative, 3 (benzene-1,3-diol)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS KEGG MMDB PC cid PC sid PDB	PubMed	644000	-18.21	n/a	n/a	n/a	7.4	25
Universita degli Studi di Firenze					Bioorg Med Chem. 16: 7424-8 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	phenol (phenol)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	B.MOAD CHEBI CSLS DrugBank KEGG MMDB PC cid PC sid PDB	PubMed	710000	-17.97	n/a	n/a	n/a	7.4	25
Universita degli Studi di Firenze					Bioorg Med Chem. 16: 7424-8 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	phenol derivative, 2 (benzene-1,2-diol)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS DrugBank KEGG MMDB PC cid PC sid PDB	PubMed	714000	-17.95	n/a	n/a	n/a	7.4	25
Universita degli Studi di Firenze					Bioorg Med Chem. 16: 7424-8 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	phenol derivative, 8 (4-hydroxybenzoic acid)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS DrugBank KEGG MMDB PC cid PC sid PDB	PubMed	716000	-17.95	n/a	n/a	n/a	7.4	25
Universita degli Studi di Firenze					Bioorg Med Chem. 16: 7424-8 (2008)
Carbonic Anhydrase VII Homo sapiens (human)	phenol derivative, 10 (4-hydroxybenzonitrile)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	777000	-17.74	n/a	n/a	n/a	7.4	25
Universita degli Studi di Firenze					Bioorg Med Chem. 16: 7424-8 (2008)

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