Compile Data Set for Download or QSAR
(2D       Computed 3D by Vconf -m prep )

Data curated solely by BindingDB

Found 114 hits of affinity data for UniProtKB/TrEMBL: P28845

Target (Institution)	Ligand	Target Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	pH	Temp °C
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	N-(Pyridin-2-yl) arylsulfonamide, 26	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	<1.000	<-50.85	n/a	n/a	n/a	8	22
Pfizer					Bioorg Med Chem Lett. 19: 3493-7 (2009)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	N-(Pyridin-2-yl) arylsulfonamide, 25	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	1.700	-49.55	n/a	n/a	n/a	8	22
Pfizer					Bioorg Med Chem Lett. 19: 3493-7 (2009)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	N-(Pyridin-2-yl) arylsulfonamide, 24	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	1.900	-49.27	n/a	n/a	n/a	8	22
Pfizer					Bioorg Med Chem Lett. 19: 3493-7 (2009)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-(S)-Phenethylamine analog 8 (2-((S)-1-(2-fluorophenyl)ethylamino)-5-isopropyl-5...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	3.000	-48.15	n/a	n/a	n/a	7.2	22
Amgen					J Med Chem. 50: 429-32 (2007)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-Amino-1,3-thiazol-4(5H)-one, 8b (2-(hexahydro-2,5-methanopentalen-3a(1H)-ylamino)-1...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	3.000	-48.15	n/a	n/a	n/a	7.2	22
Biovitrum AB					J Med Chem. 51: 2933-43 (2008)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	N-(Pyridin-2-yl) arylsulfonamide, 22	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	4.000	-47.45	n/a	n/a	n/a	8	22
Pfizer					Bioorg Med Chem Lett. 19: 3493-7 (2009)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-(S)-Phenethylamine analog 11 ((5S)-2-{[(1S)-1-(2-fluorophenyl)ethyl]amino}-5-met...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	4.000	-47.45	n/a	n/a	n/a	7.2	22
Amgen					J Med Chem. 50: 429-32 (2007)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	N-(Pyridin-2-yl) arylsulfonamide, 28	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	4.800	-47.00	n/a	n/a	n/a	8	22
Pfizer					Bioorg Med Chem Lett. 19: 3493-7 (2009)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	N-(Pyridin-2-yl) arylsulfonamide, 20	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	5.800	-46.53	n/a	n/a	n/a	8	22
Pfizer					Bioorg Med Chem Lett. 19: 3493-7 (2009)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	N-(Pyridin-2-yl) arylsulfonamide, 23	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	6.600	-46.22	n/a	n/a	n/a	8	22
Pfizer					Bioorg Med Chem Lett. 19: 3493-7 (2009)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-(S)-Phenethylamine analog 10 (2-((S)-1-(2-bromophenyl)ethylamino)-5-isopropyl-5-...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	7.000	-46.07	n/a	n/a	n/a	7.2	22
Amgen					J Med Chem. 50: 429-32 (2007)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-(S)-Phenethylamine analog 9 (2-((S)-1-(2-chlorophenyl)ethylamino)-5-isopropyl-5...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	8.000	-45.75	n/a	n/a	n/a	7.2	22
Amgen					J Med Chem. 50: 429-32 (2007)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-(S)-Phenethylamine analog 12 ((5R)-2-{[(1S)-1-(2-fluorophenyl)ethyl]amino}-5-met...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	9.000	-45.46	n/a	n/a	n/a	7.2	22
Amgen					J Med Chem. 50: 429-32 (2007)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	N-(Pyridin-2-yl) arylsulfonamide, 27	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	9.800	-45.25	n/a	n/a	n/a	8	22
Pfizer					Bioorg Med Chem Lett. 19: 3493-7 (2009)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-Amino-1,3-thiazol-4(5H)-one, 6h (5-methyl-5-propyl-2-{tricyclo[3.3.1.0^{3,7}]nonan-...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	12.00	-44.75	n/a	n/a	n/a	7.2	22
Biovitrum AB					J Med Chem. 51: 2933-43 (2008)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-Amino-1,3-thiazol-4(5H)-one, 7b (5,5-diethyl-2-{tricyclo[3.3.1.0^{3,7}]nonan-3-ylam...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	13.00	-44.55	n/a	n/a	n/a	7.2	22
Biovitrum AB					J Med Chem. 51: 2933-43 (2008)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-Amino-1,3-thiazol-4(5H)-one, 5h (5-ethyl-5-methyl-2-{tricyclo[3.3.1.0^{3,7}]nonan-3...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	13.00	-44.55	n/a	n/a	n/a	7.2	22
Biovitrum AB					J Med Chem. 51: 2933-43 (2008)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-Amino-1,3-thiazol-4(5H)-one, 8a (2-(cyclooctylamino)-1-thia-3-azaspiro[4.4]non-2-en...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	14.00	-44.37	n/a	n/a	n/a	7.2	22
Biovitrum AB					J Med Chem. 51: 2933-43 (2008)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-(S)-Phenethylamine analog 7 (5-isopropyl-5-methyl-2-((S)-1-(2-(trifluoromethyl)...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	18.00	-43.76	n/a	n/a	n/a	7.2	22
Amgen					J Med Chem. 50: 429-32 (2007)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-(S)-Phenethylamine analog 14 (2- ((S)-1-(2-fluorophenyl)ethylamino)-5-(2-fluorop...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	18.00	-43.76	n/a	n/a	n/a	7.2	22
Amgen					J Med Chem. 50: 429-32 (2007)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	N-(Pyridin-2-yl) arylsulfonamide, 19	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	20.00	-43.50	n/a	n/a	n/a	8	22
Pfizer					Bioorg Med Chem Lett. 19: 3493-7 (2009)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-Amino-1,3-thiazol-4(5H)-one, 7c (2-(adamantan-1-ylamino)-5,5-diethyl-4,5-dihydro-1,...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	20.00	-43.50	n/a	n/a	n/a	7.2	22
Biovitrum AB					J Med Chem. 51: 2933-43 (2008)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-(S)-Phenethylamine analog 15 (2-{[(1S)-1-(2-fluorophenyl)ethyl]amino}-5-methyl-5...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	20.00	-43.50	n/a	n/a	n/a	7.2	22
Amgen					J Med Chem. 50: 429-32 (2007)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-(S)-Phenethylamine analog 17 ((5S)-2-{[(1S)-1-(2-fluorophenyl)ethyl]amino}-5-met...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS MMDB PC cid PC sid PDB	MMDB PDB PubMed	22.00	-43.26	n/a	n/a	n/a	7.2	22
Amgen					J Med Chem. 50: 429-32 (2007)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-Amino-1,3-thiazol-4(5H)-one, 5i (2-(adamantan-1-ylamino)-5-ethyl-5-methyl-4,5-dihyd...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	24.00	-43.05	n/a	n/a	n/a	7.2	22
Biovitrum AB					J Med Chem. 51: 2933-43 (2008)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-Amino-1,3-thiazol-4(5H)-one, 6i (2-(adamantan-1-ylamino)-5-methyl-5-propyl-4,5-dihy...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	24.00	-43.05	n/a	n/a	n/a	7.2	22
Biovitrum AB					J Med Chem. 51: 2933-43 (2008)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-Amino-1,3-thiazol-4(5H)-one, 6f (2-{bicyclo[2.2.1]heptan-1-ylamino}-5-methyl-5-prop...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	25.00	-42.95	n/a	n/a	n/a	7.2	22
Biovitrum AB					J Med Chem. 51: 2933-43 (2008)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-Amino-1,3-thiazol-4(5H)-one, 7a (2-(cyclooctylamino)-5,5-diethyl-4,5-dihydro-1,3-th...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	26.00	-42.85	n/a	n/a	n/a	7.2	22
Biovitrum AB					J Med Chem. 51: 2933-43 (2008)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-Amino-1,3-thiazol-4(5H)-one, 8c (2-(adamantan-1-ylamino)-1-thia-3-azaspiro[4.4]non-...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	28.00	-42.67	n/a	n/a	n/a	7.2	22
Biovitrum AB					J Med Chem. 51: 2933-43 (2008)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-Amino-1,3-thiazol-4(5H)-one, 6d (2-(cyclooctylamino)-5-methyl-5-propyl-4,5-dihydro-...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid PDB	PDB PubMed	28.00	-42.67	n/a	n/a	n/a	7.2	22
Biovitrum AB					J Med Chem. 51: 2933-43 (2008)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-Amino-1,3-thiazol-4(5H)-one, 6c (2-(cycloheptylamino)-5-methyl-5-propyl-4,5-dihydro...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	32.00	-42.34	n/a	n/a	n/a	7.2	22
Biovitrum AB					J Med Chem. 51: 2933-43 (2008)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-Amino-1,3-thiazol-4(5H)-one, 6b (2-[(cyclohexylmethyl)amino]-5-methyl-5-propyl-4,5-...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	34.00	-42.19	n/a	n/a	n/a	7.2	22
Biovitrum AB					J Med Chem. 51: 2933-43 (2008)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-Amino-1,3-thiazol-4(5H)-one, 6e (5-methyl-5-propyl-2-[(2,2,3,3-tetramethylcycloprop...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	38.00	-41.92	n/a	n/a	n/a	7.2	22
Biovitrum AB					J Med Chem. 51: 2933-43 (2008)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-(S)-Phenethylamine analog 6 (5-isopropyl-5-methyl-2-((S)-1-(3-(trifluoromethyl)...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	45.00	-41.51	n/a	n/a	n/a	7.2	22
Amgen					J Med Chem. 50: 429-32 (2007)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-Amino-1,3-thiazol-4(5H)-one, 5d (2-(cyclooctylamino)-5-ethyl-5-methyl-4,5-dihydro-1...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	47.00	-41.40	n/a	n/a	n/a	7.2	22
Biovitrum AB					J Med Chem. 51: 2933-43 (2008)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-(S)-Phenethylamine analog 16 ((5R)-2-{[(1S)-1-(2-fluorophenyl)ethyl]amino}-5-met...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	48.00	-41.35	n/a	n/a	n/a	7.2	22
Amgen					J Med Chem. 50: 429-32 (2007)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	N-(Pyridin-2-yl) arylsulfonamide, 18	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	48.00	-41.35	n/a	n/a	n/a	8	22
Pfizer					Bioorg Med Chem Lett. 19: 3493-7 (2009)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-Benzylamine analog 3 (5-isopropyl-5-methyl-2-((S)-1-phenylethylamino)thi...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	50.00	-41.25	n/a	n/a	n/a	7.2	22
Amgen					J Med Chem. 50: 429-32 (2007)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-Amino-1,3-thiazol-4(5H)-one, 6a (2-(cyclohexylamino)-5-methyl-5-propyl-4,5-dihydro-...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	55.00	-41.01	n/a	n/a	n/a	7.2	22
Biovitrum AB					J Med Chem. 51: 2933-43 (2008)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-Amino-1,3-thiazol-4(5H)-one, 5e (5-ethyl-5-methyl-2-[(2,2,3,3-tetramethylcyclopropy...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	58.00	-40.88	n/a	n/a	n/a	7.2	22
Biovitrum AB					J Med Chem. 51: 2933-43 (2008)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	N-(Pyridin-2-yl) arylsulfonamide, 21	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	62.00	-40.72	n/a	n/a	n/a	8	22
Pfizer					Bioorg Med Chem Lett. 19: 3493-7 (2009)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-Amino-1,3-thiazol-4(5H)-one, 5b (2-[(cyclohexylmethyl)amino]-5-ethyl-5-methyl-4,5-d...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	64.00	-40.64	n/a	n/a	n/a	7.2	22
Biovitrum AB					J Med Chem. 51: 2933-43 (2008)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-Benzylamine analog 2 (2-(benzylamino)-5-isopropyl-5-methylthiazol-4(5H)-...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	65.00	-40.60	n/a	n/a	n/a	7.2	22
Amgen					J Med Chem. 50: 429-32 (2007)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-Amino-1,3-thiazol-4(5H)-one, 5f (2-{bicyclo[2.2.1]heptan-1-ylamino}-5-ethyl-5-methy...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	73.00	-40.32	n/a	n/a	n/a	7.2	22
Biovitrum AB					J Med Chem. 51: 2933-43 (2008)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-Amino-1,3-thiazol-4(5H)-one, 5c (2-(cycloheptylamino)-5-ethyl-5-methyl-4,5-dihydro-...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	82.00	-40.03	n/a	n/a	n/a	7.2	22
Biovitrum AB					J Med Chem. 51: 2933-43 (2008)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	N-(Pyridin-2-yl) arylsulfonamide, 16	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	84.00	-39.98	n/a	n/a	n/a	8	22
Pfizer					Bioorg Med Chem Lett. 19: 3493-7 (2009)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-(S)-Phenethylamine analog 5 (5-isopropyl-5-methyl-2-((S)-1-(4-(trifluoromethyl)...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	87.00	-39.89	n/a	n/a	n/a	7.2	22
Amgen					J Med Chem. 50: 429-32 (2007)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	N-(Pyridin-2-yl) arylsulfonamide, 12	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	108.0	-39.36	n/a	n/a	n/a	8	22
Pfizer					Bioorg Med Chem Lett. 19: 3493-7 (2009)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-Amino-1,3-thiazol-4(5H)-one, 5a (2-(cyclohexylamino)-5-ethyl-5-methyl-4,5-dihydro-1...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	126.0	-38.98	n/a	n/a	n/a	7.2	22
Biovitrum AB					J Med Chem. 51: 2933-43 (2008)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	2-Benzylamine analog 4 (5-isopropyl-5-methyl-2-((R)-1-phenylethylamino)thi...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	130.0	-38.90	n/a	n/a	n/a	7.2	22
Amgen					J Med Chem. 50: 429-32 (2007)

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