Found 951 hits of affinity data for UniProtKB/TrEMBL: P28845Target
(Institution) | Ligand | Target
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | pH | Temp
°C |
|---|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens (human) | N-(Pyridin-2-yl) arylsulfonamide, 26
| B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| PC cid
PC sid
| PubMed
| <1.000 | <-50.85 | n/a | n/a | n/a | 8 | 22 |
Pfizer
|
Bioorg Med Chem Lett. 19: 3493-7 (2009)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:558059
(1-(((R)-3-methyl-4-(4-((S)-1,1,1-trifluoro-2-hydro...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PDB
| PDB
PubMed
| 1.100 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
|
Bioorg Med Chem. 16: 8922-31 (2008)
 |
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens (human) | N-(Pyridin-2-yl) arylsulfonamide, 25
| B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| PC cid
PC sid
| PubMed
| 1.700 | -49.55 | n/a | n/a | n/a | 8 | 22 |
Pfizer
|
Bioorg Med Chem Lett. 19: 3493-7 (2009)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens (human) | N-(Pyridin-2-yl) arylsulfonamide, 24
| B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| PC cid
PC sid
| PubMed
| 1.900 | -49.27 | n/a | n/a | n/a | 8 | 22 |
Pfizer
|
Bioorg Med Chem Lett. 19: 3493-7 (2009)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:469190
(1-piperidin-1-yl-cyclopropanecarboxylic acid (5-hy...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PC cid
PC sid
| PubMed
| 2.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott
Curated by ChEMBL
|
Bioorg Med Chem Lett. 16: 5958-62 (2006)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:558059
(1-(((R)-3-methyl-4-(4-((S)-1,1,1-trifluoro-2-hydro...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PDB
| PDB
PubMed
| 2.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
|
Bioorg Med Chem. 16: 8922-31 (2008)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:465500
(N-(5-hydroxy-adamantan-2-yl)-2-(3-trifluoromethyl-...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PC cid
PC sid
| PubMed
| 3.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
|
J Med Chem. 50: 149-64 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens (human) | 2-(S)-Phenethylamine analog 8
(2-((S)-1-(2-fluorophenyl)ethylamino)-5-isopropyl-5...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| PC cid
PC sid
| PubMed
| 3.000 | -48.15 | n/a | n/a | n/a | 7.2 | 22 |
Amgen
|
J Med Chem. 50: 429-32 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens (human) | 2-Amino-1,3-thiazol-4(5H)-one, 8b
(2-(hexahydro-2,5-methanopentalen-3a(1H)-ylamino)-1...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| PC cid
PC sid
| PubMed
| 3.000 | -48.15 | n/a | n/a | n/a | 7.2 | 22 |
Biovitrum AB
|
J Med Chem. 51: 2933-43 (2008)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:508528
(2-(2,6-dichloro-4-fluoro-phenoxy)-2-methyl-N-(5-su...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PC cid
PC sid
| PubMed
| 3.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott
Curated by ChEMBL
|
Bioorg Med Chem Lett. 17: 527-32 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:465672
((R)-N-[(E)-5-hydroxy-2-adamantyl]-2-{4-[5-(trifluo...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PC cid
PC sid
| PubMed
| 4.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
|
J Med Chem. 50: 149-64 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:465664
(N-[(1R,3S)-5-hydroxy-2-adamantyl]-2-(6,7,9,10-tetr...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PC cid
PC sid
| PubMed
| 4.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
|
J Med Chem. 50: 149-64 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:498575
(2-(adamantan-1-ylamino)-5,5-diethyl-oxazol-4-one) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
| PubMed
| 4.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
|
Bioorg Med Chem Lett. 17: 4837-40 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:498577
(2-(1-adamantylamino)-1-oxa-3-azaspiro[4.4]non-2-en...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
| PubMed
| 4.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
|
Bioorg Med Chem Lett. 17: 4837-40 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:469021
((4-amino-3,5-dichlorophenyl)(1,3,3-trimethyl-6-aza...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PC cid
PC sid
| PubMed
| 4.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
|
Bioorg Med Chem Lett. 16: 6241-5 (2006)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:469028
((4-amino-3,5-dichloro-phenyl)-(2-aza-tricyclo[3.3....) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PC cid
PC sid
| PubMed
| 4.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
|
Bioorg Med Chem Lett. 16: 6241-5 (2006)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:508512
(2-(3-chloro-phenoxy)-2-methyl-N-(5-sulfamoyl-adama...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PC cid
PC sid
| PubMed
| 4.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott
Curated by ChEMBL
|
Bioorg Med Chem Lett. 17: 527-32 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:508510
(2-(2-chloro-phenoxy)-2-methyl-N-(5-sulfamoyl-adama...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PC cid
PC sid
| PubMed
| 4.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott
Curated by ChEMBL
|
Bioorg Med Chem Lett. 17: 527-32 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens (human) | 2-(S)-Phenethylamine analog 11
((5S)-2-{[(1S)-1-(2-fluorophenyl)ethyl]amino}-5-met...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CSLS
PC cid
PC sid
| PubMed
| 4.000 | -47.45 | n/a | n/a | n/a | 7.2 | 22 |
Amgen
|
J Med Chem. 50: 429-32 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens (human) | N-(Pyridin-2-yl) arylsulfonamide, 22
| B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| PC cid
PC sid
| PubMed
| 4.000 | -47.45 | n/a | n/a | n/a | 8 | 22 |
Pfizer
|
Bioorg Med Chem Lett. 19: 3493-7 (2009)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens (human) | N-(Pyridin-2-yl) arylsulfonamide, 28
| B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CSLS
PC cid
PC sid
| PubMed
| 4.800 | -47.00 | n/a | n/a | n/a | 8 | 22 |
Pfizer
|
Bioorg Med Chem Lett. 19: 3493-7 (2009)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:508533
(2-(4-chloro-phenoxy)-2-methyl-N-(5-sulfamoyl-adama...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PC cid
PC sid
| PubMed
| 5.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott
Curated by ChEMBL
|
Bioorg Med Chem Lett. 17: 527-32 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:465490
(N-[(E)-5-hydroxy-2-adamantyl]-2-{4-[5-(trifluorome...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PC cid
PC sid
| PubMed
| 5.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
|
J Med Chem. 50: 149-64 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:465459
(N-adamantan-2-yl-2-[4-(4-chloro-phenyl)-piperazin-...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PC cid
PC sid
| PubMed
| 5.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
|
J Med Chem. 50: 149-64 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:465663
(2-[3-(2-fluoro-phenoxy)-azetidin-1-yl]-N-(5-hydrox...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PC cid
PC sid
| PubMed
| 5.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
|
J Med Chem. 50: 149-64 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:508495
(2-(2-chloro-phenoxy)-N-(5-methanesulfonyl-adamanta...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PC cid
PC sid
| PubMed
| 5.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott
Curated by ChEMBL
|
Bioorg Med Chem Lett. 17: 527-32 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:469172
(4-[2-(3,3-difluoro-piperidin-1-yl)-butyrylamino]-a...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PC cid
PC sid
| PubMed
| 5.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott
Curated by ChEMBL
|
Bioorg Med Chem Lett. 16: 5958-62 (2006)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:501619
(5-cyclopentyl-2-(2-fluorophenylamino)thiazol-4(5H)...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
| PubMed
| 5.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
|
Bioorg Med Chem Lett. 17: 6056-61 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens (human) | N-(Pyridin-2-yl) arylsulfonamide, 20
| B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| PC cid
PC sid
| PubMed
| 5.800 | -46.53 | n/a | n/a | n/a | 8 | 22 |
Pfizer
|
Bioorg Med Chem Lett. 19: 3493-7 (2009)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:508526
(2-(2-chloro-4-fluoro-phenoxy)-2-methyl-N-(5-sulfam...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PC cid
PC sid
| PubMed
| 6.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott
Curated by ChEMBL
|
Bioorg Med Chem Lett. 17: 527-32 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:469191
(1-piperidin-1-yl-cyclopropanecarboxylic acid (5-hy...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PC cid
PC sid
| PubMed
| 6.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott
Curated by ChEMBL
|
Bioorg Med Chem Lett. 16: 5958-62 (2006)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:465492
((E)-N-(5-methoxy-adamantan-2-yl)-2-[4-(5-trifluoro...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PC cid
PC sid
| PubMed
| 6.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
|
J Med Chem. 50: 149-64 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:498573
(2-(adamantan-2-ylamino)-5-isopropyl-5-methyl-oxazo...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
| PubMed
| 6.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
|
Bioorg Med Chem Lett. 17: 4837-40 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:498576
(2-(adamantan-1-ylamino)-5-isopropyl-5-methyl-oxazo...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
| PubMed
| 6.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
|
Bioorg Med Chem Lett. 17: 4837-40 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:469125
(4-{2-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazin...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PC cid
PC sid
| PubMed
| 6.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott
Curated by ChEMBL
|
Bioorg Med Chem Lett. 16: 5958-62 (2006)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:469133
(4-{2-cyclopropyl-2-[4-(5-trifluoromethyl-pyridin-2...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PC cid
PC sid
| PubMed
| 6.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott
Curated by ChEMBL
|
Bioorg Med Chem Lett. 16: 5958-62 (2006)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:465487
(N-(7-hydroxy-5-methoxy-adamantan-2-yl)-2-[4-(5-tri...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PC cid
PC sid
| PubMed
| 6.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
|
J Med Chem. 50: 149-64 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:501616
(2-(2-chlorophenylamino)-5-cyclopentylthiazol-4(5H)...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
| PubMed
| 6.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
|
Bioorg Med Chem Lett. 17: 6056-61 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens (human) | N-(Pyridin-2-yl) arylsulfonamide, 23
| B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| PC cid
PC sid
| PubMed
| 6.600 | -46.22 | n/a | n/a | n/a | 8 | 22 |
Pfizer
|
Bioorg Med Chem Lett. 19: 3493-7 (2009)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:498571
(2-(2-adamantylamino)-5-methyl-5-(trifluoromethyl)-...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
| PubMed
| 7.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
|
Bioorg Med Chem Lett. 17: 4837-40 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:469139
(4-({1-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazi...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PC cid
PC sid
| PubMed
| 7.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott
Curated by ChEMBL
|
Bioorg Med Chem Lett. 16: 5958-62 (2006)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens (human) | 2-(S)-Phenethylamine analog 10
(2-((S)-1-(2-bromophenyl)ethylamino)-5-isopropyl-5-...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CSLS
PC cid
PC sid
| PubMed
| 7.000 | -46.07 | n/a | n/a | n/a | 7.2 | 22 |
Amgen
|
J Med Chem. 50: 429-32 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:501620
((5R)-2-[(2-fluorophenyl)amino]-5-(1-methylethyl)-1...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PDB
| PDB
PubMed
| 7.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
|
Bioorg Med Chem Lett. 17: 6056-61 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:465672
((R)-N-[(E)-5-hydroxy-2-adamantyl]-2-{4-[5-(trifluo...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PC cid
PC sid
| PubMed
| 7.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
|
J Med Chem. 50: 149-64 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:469198
(4-({1-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazi...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PC cid
PC sid
| PubMed
| 7.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott
Curated by ChEMBL
|
Bioorg Med Chem Lett. 16: 5958-62 (2006)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:508483
(2-(2-chloro-4-fluoro-phenoxy)-N-(5-methanesulfonyl...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PC cid
PC sid
| PubMed
| 7.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott
Curated by ChEMBL
|
Bioorg Med Chem Lett. 17: 527-32 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:508524
(2-methyl-N-(5-sulfamoyl-adamantan-2-yl)-2-(2-trifl...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PC cid
PC sid
| PubMed
| 7.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott
Curated by ChEMBL
|
Bioorg Med Chem Lett. 17: 527-32 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:508498
(2-(4-chloro-phenoxy)-N-(5-methanesulfonyl-adamanta...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PC cid
PC sid
| PubMed
| 7.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott
Curated by ChEMBL
|
Bioorg Med Chem Lett. 17: 527-32 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:508499
(N-(5-methanesulfonyl-adamantan-2-yl)-2-methyl-2-(2...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
PC cid
PC sid
| PubMed
| 7.000 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott
Curated by ChEMBL
|
Bioorg Med Chem Lett. 17: 527-32 (2007)
|
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1)
Homo sapiens | CHEBI:501584
(2-(2-chlorophenylamino)-5-isopropylthiazol-4(5H)-o...) | B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
| CHEBI
CSLS
| PubMed
| 7.200 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
|
Bioorg Med Chem Lett. 17: 6056-61 (2007)
|
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