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Compile Data Set for Download or QSAR

Found 3 hits of ki data for polymerid = 1407   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
11-beta-hydroxysteroid dehydrogenase 2


(Homo sapiens (human))
BDBM50210884
PNG
(1-(1-(3-methoxy-4-methylbenzoyl)piperidin-4-yl)-1H...)
Show SMILES COc1cc(ccc1C)C(=O)N1CCC(CC1)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C21H23N3O3/c1-14-7-8-15(13-19(14)27-2)20(25)23-11-9-16(10-12-23)24-18-6-4-3-5-17(18)22-21(24)26/h3-8,13,16H,9-12H2,1-2H3,(H,22,26)
KEGG

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PC cid
PC sid
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Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Biovitrum AB

Curated by ChEMBL


Assay Description
Inhibition of 11betaHSD2


Bioorg Med Chem Lett 17: 3421-5 (2007)

More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 2


(Homo sapiens (human))
BDBM50317206
PNG
((3-Phenyl-adamantan-1-yl)-piperidin-1-yl-methanone...)
Show SMILES O=C(N1CCCCC1)C12CC3CC(C1)CC(C3)(C2)c1ccccc1
Show InChI InChI=1S/C22H29NO/c24-20(23-9-5-2-6-10-23)22-14-17-11-18(15-22)13-21(12-17,16-22)19-7-3-1-4-8-19/h1,3-4,7-8,17-18H,2,5-6,9-16H2
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Pfizer Global Research& Development

Curated by ChEMBL


Assay Description
Inhibition of 11-beta-HSD2


Bioorg Med Chem Lett 20: 2897-902 (2010)

More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 2


(Homo sapiens (human))
BDBM50216917
PNG
(2-(cyclooctylamino)-5,5-diethyloxazol-4(5H)-one | ...)
Show SMILES CCC1(CC)OC(NC2CCCCCCC2)=NC1=O
Show InChI InChI=1S/C15H26N2O2/c1-3-15(4-2)13(18)17-14(19-15)16-12-10-8-6-5-7-9-11-12/h12H,3-11H2,1-2H3,(H,16,17,18)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Biovitrum AB

Curated by ChEMBL


Assay Description
Binding affinity to human 11beta-HSD2


Bioorg Med Chem Lett 17: 4837-40 (2007)

More data for this
Ligand-Target Pair