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Compile Data Set for Download or QSAR

Found 295 hits of ic50 data for polymerid = 1409   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50247012
PNG
(3beta-O-Succinyl-18-beta-glycyrrhetinic acid | Car...)
Show SMILES CC1(C)[C@H](CC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2C(=O)C=C2[C@@H]3C[C@](C)(CC[C@]3(C)CC[C@@]12C)C(O)=O)OC(=O)CCC(O)=O
Show InChI InChI=1S/C34H50O7/c1-29(2)23-10-13-34(7)27(32(23,5)12-11-24(29)41-26(38)9-8-25(36)37)22(35)18-20-21-19-31(4,28(39)40)15-14-30(21,3)16-17-33(20,34)6/h18,21,23-24,27H,8-17,19H2,1-7H3,(H,36,37)(H,39,40)/t21-,23-,24-,27+,30+,31-,32-,33+,34+/m0/s1
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n/an/a 82n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of mouse microsomal 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...


Bioorg Med Chem Lett 19: 4455-8 (2009)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM13757
PNG
((1R,3R,4S,7S)-4-[2-(2-chlorophenoxy)-2-methylpropa...)
Show SMILES CC(C)(Oc1ccccc1Cl)C(=O)N[C@H]1C2C[C@@H]3C[C@@H]1C[C@](C3)(C2)C(O)=O
Show InChI InChI=1S/C21H26ClNO4/c1-20(2,27-16-6-4-3-5-15(16)22)18(24)23-17-13-7-12-8-14(17)11-21(9-12,10-13)19(25)26/h3-6,12-14,17H,7-11H2,1-2H3,(H,23,24)(H,25,26)/t12-,13+,14?,17+,21+/m0/s1
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n/an/a 140n/an/an/an/an/an/a



Abbott Laboratories



Assay Description
The in Vitro 11beta-HSD2 dehydrogenase assays were developed using the cell lysates that had the full length human or mouse 11beta-HSD2 cDNA over exp...


Bioorg Med Chem Lett 17: 750-5 (2007)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50340383
PNG
(5-(4-(5,6,7,8,9,10-hexahydro-[1,2,4]triazolo[4,3-a...)
Show SMILES CC(O)CCCC12CCC(CC1)(CC2)c1nnc2CCCCCCn12
Show InChI InChI=1S/C21H35N3O/c1-17(25)7-6-9-20-10-13-21(14-11-20,15-12-20)19-23-22-18-8-4-2-3-5-16-24(18)19/h17,25H,2-16H2,1H3
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n/an/a 190n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta-HSD2 expressed in CHO-K1 cells assessed as conversion of [3H]-cortisol to [3H]-cortisone by scintillation proximity assay


Bioorg Med Chem Lett 21: 2568-72 (2011)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50247012
PNG
(3beta-O-Succinyl-18-beta-glycyrrhetinic acid | Car...)
Show SMILES CC1(C)[C@H](CC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2C(=O)C=C2[C@@H]3C[C@](C)(CC[C@]3(C)CC[C@@]12C)C(O)=O)OC(=O)CCC(O)=O
Show InChI InChI=1S/C34H50O7/c1-29(2)23-10-13-34(7)27(32(23,5)12-11-24(29)41-26(38)9-8-25(36)37)22(35)18-20-21-19-31(4,28(39)40)15-14-30(21,3)16-17-33(20,34)6/h18,21,23-24,27H,8-17,19H2,1-7H3,(H,36,37)(H,39,40)/t21-,23-,24-,27+,30+,31-,32-,33+,34+/m0/s1
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n/an/a 206n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [3H]cortisone into [3H]cortisol by scintillation proximity assay


J Nat Prod 75: 599-604 (2012)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM13758
PNG
((1R,3R,4S,7S)-4-[2-(3-chlorophenoxy)-2-methylpropa...)
Show SMILES CC(C)(Oc1cccc(Cl)c1)C(=O)N[C@H]1C2C[C@@H]3C[C@@H]1C[C@](C3)(C2)C(O)=O
Show InChI InChI=1S/C21H26ClNO4/c1-20(2,27-16-5-3-4-15(22)8-16)18(24)23-17-13-6-12-7-14(17)11-21(9-12,10-13)19(25)26/h3-5,8,12-14,17H,6-7,9-11H2,1-2H3,(H,23,24)(H,25,26)/t12-,13+,14?,17+,21+/m0/s1
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n/an/a 540n/an/an/an/an/an/a



Abbott Laboratories



Assay Description
The in Vitro 11beta-HSD2 dehydrogenase assays were developed using the cell lysates that had the full length human or mouse 11beta-HSD2 cDNA over exp...


Bioorg Med Chem Lett 17: 750-5 (2007)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50195290
PNG
(4-{2-methyl-2-[4-(5-trifluoromethyl-pyridin-2-yl)-...)
Show SMILES CC(C)(N1CCN(CC1)c1ccc(cn1)C(F)(F)F)C(=O)N[C@H]1C2C[C@H]3CC1C[C@](C3)(C2)C(O)=O
Show InChI InChI=1S/C25H33F3N4O3/c1-23(2,32-7-5-31(6-8-32)19-4-3-18(14-29-19)25(26,27)28)21(33)30-20-16-9-15-10-17(20)13-24(11-15,12-16)22(34)35/h3-4,14-17,20H,5-13H2,1-2H3,(H,30,33)(H,34,35)/t15-,16?,17?,20-,24-
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n/an/a 780n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta-HSD2 assessed as cortisol disappearance by SPA


Bioorg Med Chem Lett 16: 5958-62 (2006)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50195295
PNG
(4-({1-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazi...)
Show SMILES OC(=O)[C@@]12CC3CC(C1)[C@H](NC(=O)C1(CCCC1)N1CCN(CC1)c1ccc(cn1)C(F)(F)F)C(C3)C2
Show InChI InChI=1S/C27H35F3N4O3/c28-27(29,30)20-3-4-21(31-16-20)33-7-9-34(10-8-33)26(5-1-2-6-26)23(35)32-22-18-11-17-12-19(22)15-25(13-17,14-18)24(36)37/h3-4,16-19,22H,1-2,5-15H2,(H,32,35)(H,36,37)/t17?,18?,19?,22-,25-
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n/an/a 1.10E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta-HSD2 assessed as cortisol disappearance by SPA


Bioorg Med Chem Lett 16: 5958-62 (2006)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM13772
PNG
(2-(2-chloro-4-fluorophenoxy)-2-methyl-N-[(1R,2S,5R...)
Show SMILES CC(C)(Oc1ccc(F)cc1Cl)C(=O)N[C@H]1C2C[C@@H]3C[C@@H]1C[C@](C3)(C2)c1nnn[nH]1
Show InChI InChI=1S/C21H25ClFN5O2/c1-20(2,30-16-4-3-14(23)7-15(16)22)19(29)24-17-12-5-11-6-13(17)10-21(8-11,9-12)18-25-27-28-26-18/h3-4,7,11-13,17H,5-6,8-10H2,1-2H3,(H,24,29)(H,25,26,27,28)/t11-,12+,13?,17+,21+/m0/s1
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n/an/a 1.20E+3n/an/an/an/an/an/a



Abbott Laboratories



Assay Description
The in Vitro 11beta-HSD2 dehydrogenase assays were developed using the cell lysates that had the full length human or mouse 11beta-HSD2 cDNA over exp...


Bioorg Med Chem Lett 17: 750-5 (2007)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM13773
PNG
((1R,3R,4S,7S)-4-[2-(2-chlorophenoxy)-2-methylpropa...)
Show SMILES CC(C)(Oc1ccccc1Cl)C(=O)N[C@H]1C2C[C@@H]3C[C@@H]1C[C@](C3)(C2)C(=O)NS(C)(=O)=O
Show InChI InChI=1S/C22H29ClN2O5S/c1-21(2,30-17-7-5-4-6-16(17)23)19(26)24-18-14-8-13-9-15(18)12-22(10-13,11-14)20(27)25-31(3,28)29/h4-7,13-15,18H,8-12H2,1-3H3,(H,24,26)(H,25,27)/t13-,14+,15?,18+,22+/m0/s1
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Abbott Laboratories



Assay Description
The in Vitro 11beta-HSD2 dehydrogenase assays were developed using the cell lysates that had the full length human or mouse 11beta-HSD2 cDNA over exp...


Bioorg Med Chem Lett 17: 750-5 (2007)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM13755
PNG
((1R,3R,4S,7S)-4-(2-methyl-2-phenoxypropanamido)ada...)
Show SMILES CC(C)(Oc1ccccc1)C(=O)N[C@H]1C2C[C@@H]3C[C@@H]1C[C@](C3)(C2)C(O)=O
Show InChI InChI=1S/C21H27NO4/c1-20(2,26-16-6-4-3-5-7-16)18(23)22-17-14-8-13-9-15(17)12-21(10-13,11-14)19(24)25/h3-7,13-15,17H,8-12H2,1-2H3,(H,22,23)(H,24,25)/t13-,14+,15?,17+,21+/m0/s1
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n/an/a 1.50E+3n/an/an/an/an/an/a



Abbott Laboratories



Assay Description
The in Vitro 11beta-HSD2 dehydrogenase assays were developed using the cell lysates that had the full length human or mouse 11beta-HSD2 cDNA over exp...


Bioorg Med Chem Lett 17: 750-5 (2007)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50193796
PNG
(3,3-dimethyl-1-[5-(1H-tetrazol-5-yl)-adamantan-2-y...)
Show SMILES CC1(C)C(COc2ccc(cn2)C(F)(F)F)CN([C@H]2C3CC4CC2C[C@](C4)(C3)c2nnn[nH]2)C1=O
Show InChI InChI=1S/C24H29F3N6O2/c1-22(2)17(12-35-18-4-3-16(10-28-18)24(25,26)27)11-33(21(22)34)19-14-5-13-6-15(19)9-23(7-13,8-14)20-29-31-32-30-20/h3-4,10,13-15,17,19H,5-9,11-12H2,1-2H3,(H,29,30,31,32)/t13?,14?,15?,17?,19-,23-
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n/an/a 1.60E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta-HSD2


Bioorg Med Chem Lett 16: 5555-60 (2006)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50195300
PNG
(4-({1-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazi...)
Show SMILES OC(=O)[C@@]12CC3CC(C1)[C@H](NC(=O)C1(CCC1)N1CCN(CC1)c1ccc(cn1)C(F)(F)F)C(C3)C2
Show InChI InChI=1S/C26H33F3N4O3/c27-26(28,29)19-2-3-20(30-15-19)32-6-8-33(9-7-32)25(4-1-5-25)22(34)31-21-17-10-16-11-18(21)14-24(12-16,13-17)23(35)36/h2-3,15-18,21H,1,4-14H2,(H,31,34)(H,35,36)/t16?,17?,18?,21-,24-
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n/an/a 1.70E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta-HSD2 assessed as cortisol disappearance by SPA


Bioorg Med Chem Lett 16: 5958-62 (2006)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM13759
PNG
((1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylpropa...)
Show SMILES CC(C)(Oc1ccc(Cl)cc1)C(=O)N[C@H]1C2C[C@@H]3C[C@@H]1C[C@](C3)(C2)C(O)=O
Show InChI InChI=1S/C21H26ClNO4/c1-20(2,27-16-5-3-15(22)4-6-16)18(24)23-17-13-7-12-8-14(17)11-21(9-12,10-13)19(25)26/h3-6,12-14,17H,7-11H2,1-2H3,(H,23,24)(H,25,26)/t12-,13+,14?,17+,21+/m0/s1
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n/an/a 1.70E+3n/an/an/an/an/an/a



Abbott Laboratories



Assay Description
The in Vitro 11beta-HSD2 dehydrogenase assays were developed using the cell lysates that had the full length human or mouse 11beta-HSD2 cDNA over exp...


Bioorg Med Chem Lett 17: 750-5 (2007)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50192685
PNG
((3s,9s)-9-(2-(4-chlorophenoxy)-2-methylpropanamido...)
Show SMILES CC(C)(Oc1ccc(Cl)cc1)C(=O)N[C@@H]1C2CCCC1C[C@H](C2)C(O)=O
Show InChI InChI=1S/C20H26ClNO4/c1-20(2,26-16-8-6-15(21)7-9-16)19(25)22-17-12-4-3-5-13(17)11-14(10-12)18(23)24/h6-9,12-14,17H,3-5,10-11H2,1-2H3,(H,22,25)(H,23,24)/t12?,13?,14-,17+
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n/an/a 1.82E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta-HSD2


Bioorg Med Chem Lett 16: 5408-13 (2006)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50174285
PNG
(3-(4-pentylbicyclo[2.2.2]octan-1-yl)-5,6,7,8,9,10-...)
Show SMILES CCCCCC12CCC(CC1)(CC2)c1nnc2CCCCCCn12
Show InChI InChI=1S/C21H35N3/c1-2-3-7-10-20-11-14-21(15-12-20,16-13-20)19-23-22-18-9-6-4-5-8-17-24(18)19/h2-17H2,1H3
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n/an/a 2.10E+3n/an/an/an/an/an/a



Merck & Co.

Curated by ChEMBL


Assay Description
Inhibitory activity against mouse 11beta-HSD2


Bioorg Med Chem Lett 15: 5266-9 (2005)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50174285
PNG
(3-(4-pentylbicyclo[2.2.2]octan-1-yl)-5,6,7,8,9,10-...)
Show SMILES CCCCCC12CCC(CC1)(CC2)c1nnc2CCCCCCn12
Show InChI InChI=1S/C21H35N3/c1-2-3-7-10-20-11-14-21(15-12-20,16-13-20)19-23-22-18-9-6-4-5-8-17-24(18)19/h2-17H2,1H3
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n/an/a 2.10E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta-HSD2 expressed in CHO-K1 cells assessed as conversion of [3H]-cortisol to [3H]-cortisone by scintillation proximity assay


Bioorg Med Chem Lett 21: 2568-72 (2011)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50195288
PNG
(4-{2-cyclopropyl-2-[4-(5-trifluoromethyl-pyridin-2...)
Show SMILES OC(=O)[C@@]12CC3CC(C1)[C@H](NC(=O)C(C1CC1)N1CCN(CC1)c1ccc(cn1)C(F)(F)F)C(C3)C2
Show InChI InChI=1S/C26H33F3N4O3/c27-26(28,29)19-3-4-20(30-14-19)32-5-7-33(8-6-32)22(16-1-2-16)23(34)31-21-17-9-15-10-18(21)13-25(11-15,12-17)24(35)36/h3-4,14-18,21-22H,1-2,5-13H2,(H,31,34)(H,35,36)/t15?,17?,18?,21-,22?,25-
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n/an/a 2.70E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta-HSD2 assessed as cortisol disappearance by SPA


Bioorg Med Chem Lett 16: 5958-62 (2006)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50195294
PNG
(4-({1-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazi...)
Show SMILES OC(=O)[C@@]12C[C@H]3CC(C1)[C@H](NC(=O)C1(CC1)N1CCN(CC1)c1ccc(cn1)C(F)(F)F)C(C3)C2
Show InChI InChI=1S/C25H31F3N4O3/c26-25(27,28)18-1-2-19(29-14-18)31-5-7-32(8-6-31)24(3-4-24)21(33)30-20-16-9-15-10-17(20)13-23(11-15,12-16)22(34)35/h1-2,14-17,20H,3-13H2,(H,30,33)(H,34,35)/t15-,16?,17?,20-,23-
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n/an/a 3.20E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta-HSD2 assessed as cortisol disappearance by SPA


Bioorg Med Chem Lett 16: 5958-62 (2006)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50195291
PNG
(4-{2-methyl-2-[4-(5-trifluoromethyl-pyridin-2-yl)-...)
Show SMILES CC(C)(N1CCN(CC1)c1ccc(cn1)C(F)(F)F)C(=O)N[C@H]1C2C[C@H]3CC1C[C@](C3)(C2)C(N)=O
Show InChI InChI=1S/C25H34F3N5O2/c1-23(2,33-7-5-32(6-8-33)19-4-3-18(14-30-19)25(26,27)28)22(35)31-20-16-9-15-10-17(20)13-24(11-15,12-16)21(29)34/h3-4,14-17,20H,5-13H2,1-2H3,(H2,29,34)(H,31,35)/t15-,16?,17?,20-,24-
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n/an/a 3.60E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta-HSD2 assessed as cortisol disappearance by SPA


Bioorg Med Chem Lett 16: 5958-62 (2006)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50174294
PNG
(CHEMBL200876 | methyl 4-(5,6,7,8,9,10-hexahydro-[1...)
Show SMILES COC(=O)C12CCC(CC1)(CC2)c1nnc2CCCCCCn12
Show InChI InChI=1S/C18H27N3O2/c1-23-16(22)18-10-7-17(8-11-18,9-12-18)15-20-19-14-6-4-2-3-5-13-21(14)15/h2-13H2,1H3
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n/an/a>4.00E+3n/an/an/an/an/an/a



Merck & Co.

Curated by ChEMBL


Assay Description
Inhibitory activity against mouse 11beta-HSD2


Bioorg Med Chem Lett 15: 5266-9 (2005)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50174289
PNG
(3-(4-(3-(cyclopropylmethyl)-1,2,4-oxadiazol-5-yl)b...)
Show SMILES C(C1CC1)c1noc(n1)C12CCC(CC1)(CC2)c1nnc2CCCCCCn12
Show InChI InChI=1S/C22H31N5O/c1-2-4-14-27-18(5-3-1)24-25-19(27)21-8-11-22(12-9-21,13-10-21)20-23-17(26-28-20)15-16-6-7-16/h16H,1-15H2
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n/an/a>4.00E+3n/an/an/an/an/an/a



Merck & Co.

Curated by ChEMBL


Assay Description
Inhibitory activity against mouse 11beta-HSD2


Bioorg Med Chem Lett 15: 5266-9 (2005)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50174279
PNG
(3-(4-(3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl)bicy...)
Show SMILES Clc1ccc(cc1)-c1noc(n1)C12CCC(CC1)(CC2)c1nnc2CCCCCCn12
Show InChI InChI=1S/C24H28ClN5O/c25-18-8-6-17(7-9-18)20-26-22(31-29-20)24-13-10-23(11-14-24,12-15-24)21-28-27-19-5-3-1-2-4-16-30(19)21/h6-9H,1-5,10-16H2
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n/an/a 4.00E+3n/an/an/an/an/an/a



Merck & Co.

Curated by ChEMBL


Assay Description
Inhibitory activity against mouse 11beta-HSD2


Bioorg Med Chem Lett 15: 5266-9 (2005)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50174280
PNG
(3-(4-(3-methyl-1,2,4-oxadiazol-5-yl)bicyclo[2.2.2]...)
Show SMILES Cc1noc(n1)C12CCC(CC1)(CC2)c1nnc2CCCCCCn12
Show InChI InChI=1S/C19H27N5O/c1-14-20-17(25-23-14)19-10-7-18(8-11-19,9-12-19)16-22-21-15-6-4-2-3-5-13-24(15)16/h2-13H2,1H3
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n/an/a>4.00E+3n/an/an/an/an/an/a



Merck & Co.

Curated by ChEMBL


Assay Description
Inhibitory activity against mouse 11beta-HSD2


Bioorg Med Chem Lett 15: 5266-9 (2005)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50239407
PNG
(3-(1-(4-chlorophenyl)cyclobutyl)-5,6,7,8,9,10-hexa...)
Show SMILES Clc1ccc(cc1)C1(CCC1)c1nnc2CCCCCCn12
Show InChI InChI=1S/C18H22ClN3/c19-15-9-7-14(8-10-15)18(11-5-12-18)17-21-20-16-6-3-1-2-4-13-22(16)17/h7-10H,1-6,11-13H2
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta HSD2


Bioorg Med Chem Lett 18: 3405-11 (2008)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50239276
PNG
(3-Adamantan-1-yl-4-methyl-5-phenyl-4H-[1,2,4]triaz...)
Show SMILES Cn1c(nnc1C12CC3CC(CC(C3)C1)C2)-c1ccccc1
Show InChI InChI=1S/C19H23N3/c1-22-17(16-5-3-2-4-6-16)20-21-18(22)19-10-13-7-14(11-19)9-15(8-13)12-19/h2-6,13-15H,7-12H2,1H3
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta HSD2


Bioorg Med Chem Lett 18: 3405-11 (2008)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50260939
PNG
(3-(3-Chloro-3'-methanesulfonyl-biphenyl-4-yl)-5-[1...)
Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1Cl)-c1cccc(c1)S(C)(=O)=O
Show InChI InChI=1S/C26H23Cl2N3O2S/c1-31-24(29-30-25(31)26(13-4-14-26)19-8-10-20(27)11-9-19)22-12-7-18(16-23(22)28)17-5-3-6-21(15-17)34(2,32)33/h3,5-12,15-16H,4,13-14H2,1-2H3
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n/an/a>4.00E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta HSD2


Bioorg Med Chem Lett 18: 3405-11 (2008)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50260937
PNG
(3-(3-Chloro-4'-methanesulfonyl-biphenyl-4-yl)-5-[1...)
Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1Cl)-c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C26H23Cl2N3O2S/c1-31-24(29-30-25(31)26(14-3-15-26)19-7-9-20(27)10-8-19)22-13-6-18(16-23(22)28)17-4-11-21(12-5-17)34(2,32)33/h4-13,16H,3,14-15H2,1-2H3
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta HSD2


Bioorg Med Chem Lett 18: 3405-11 (2008)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50261050
PNG
(3-(3-Chloro-3'-ethanesulfonyl-biphenyl-4-yl)-5-[1-...)
Show SMILES CCS(=O)(=O)c1cccc(c1)-c1ccc(-c2nnc(n2C)C2(CCC2)c2ccc(Cl)cc2)c(Cl)c1
Show InChI InChI=1S/C27H25Cl2N3O2S/c1-3-35(33,34)22-7-4-6-18(16-22)19-8-13-23(24(29)17-19)25-30-31-26(32(25)2)27(14-5-15-27)20-9-11-21(28)12-10-20/h4,6-13,16-17H,3,5,14-15H2,1-2H3
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta HSD2


Bioorg Med Chem Lett 18: 3405-11 (2008)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50261010
PNG
(3-(3-Chloro-2'-ethanesulfonyl-biphenyl-4-yl)-5-[1-...)
Show SMILES CCS(=O)(=O)c1ccccc1-c1ccc(-c2nnc(n2C)C2(CCC2)c2ccc(Cl)cc2)c(Cl)c1
Show InChI InChI=1S/C27H25Cl2N3O2S/c1-3-35(33,34)24-8-5-4-7-21(24)18-9-14-22(23(29)17-18)25-30-31-26(32(25)2)27(15-6-16-27)19-10-12-20(28)13-11-19/h4-5,7-14,17H,3,6,15-16H2,1-2H3
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta HSD2


Bioorg Med Chem Lett 18: 3405-11 (2008)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50260911
PNG
(3-(3-Chloro-2'-ethylsulfanyl-biphenyl-4-yl)-5-[1-(...)
Show SMILES CCSc1ccccc1-c1ccc(-c2nnc(n2C)C2(CCC2)c2ccc(Cl)cc2)c(Cl)c1
Show InChI InChI=1S/C27H25Cl2N3S/c1-3-33-24-8-5-4-7-21(24)18-9-14-22(23(29)17-18)25-30-31-26(32(25)2)27(15-6-16-27)19-10-12-20(28)13-11-19/h4-5,7-14,17H,3,6,15-16H2,1-2H3
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n/an/a>4.00E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta HSD2


Bioorg Med Chem Lett 18: 3405-11 (2008)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50261009
PNG
(3-(3-Chloro-4'-ethanesulfonyl-biphenyl-4-yl)-5-[1-...)
Show SMILES CCS(=O)(=O)c1ccc(cc1)-c1ccc(-c2nnc(n2C)C2(CCC2)c2ccc(Cl)cc2)c(Cl)c1
Show InChI InChI=1S/C27H25Cl2N3O2S/c1-3-35(33,34)22-12-5-18(6-13-22)19-7-14-23(24(29)17-19)25-30-31-26(32(25)2)27(15-4-16-27)20-8-10-21(28)11-9-20/h5-14,17H,3-4,15-16H2,1-2H3
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta HSD2


Bioorg Med Chem Lett 18: 3405-11 (2008)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50260909
PNG
(1-(3-chloro-4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-...)
Show SMILES Cc1nc2ccccc2n1-c1ccc(-c2nnc(n2C)C2(CCC2)c2ccc(Cl)cc2)c(Cl)c1
Show InChI InChI=1S/C27H23Cl2N5/c1-17-30-23-6-3-4-7-24(23)34(17)20-12-13-21(22(29)16-20)25-31-32-26(33(25)2)27(14-5-15-27)18-8-10-19(28)11-9-18/h3-4,6-13,16H,5,14-15H2,1-2H3
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta HSD2


Bioorg Med Chem Lett 18: 3405-11 (2008)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50261008
PNG
(3-(2-chloro-4-(2-(methylsulfonyl)-1H-imidazol-1-yl...)
Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1Cl)-n1ccnc1S(C)(=O)=O
Show InChI InChI=1S/C23H21Cl2N5O2S/c1-29-20(27-28-21(29)23(10-3-11-23)15-4-6-16(24)7-5-15)18-9-8-17(14-19(18)25)30-13-12-26-22(30)33(2,31)32/h4-9,12-14H,3,10-11H2,1-2H3
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta HSD2


Bioorg Med Chem Lett 18: 3405-11 (2008)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50261007
PNG
(3-(2-chloro-4-(2-(methylthio)-1H-imidazol-1-yl)phe...)
Show SMILES CSc1nccn1-c1ccc(-c2nnc(n2C)C2(CCC2)c2ccc(Cl)cc2)c(Cl)c1
Show InChI InChI=1S/C23H21Cl2N5S/c1-29-20(18-9-8-17(14-19(18)25)30-13-12-26-22(30)31-2)27-28-21(29)23(10-3-11-23)15-4-6-16(24)7-5-15/h4-9,12-14H,3,10-11H2,1-2H3
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta HSD2


Bioorg Med Chem Lett 18: 3405-11 (2008)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50260967
PNG
(3-(2-chloro-4-(2-(trifluoromethyl)-1H-imidazol-1-y...)
Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1Cl)-n1ccnc1C(F)(F)F
Show InChI InChI=1S/C23H18Cl2F3N5/c1-32-19(30-31-20(32)22(9-2-10-22)14-3-5-15(24)6-4-14)17-8-7-16(13-18(17)25)33-12-11-29-21(33)23(26,27)28/h3-8,11-13H,2,9-10H2,1H3
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta HSD2


Bioorg Med Chem Lett 18: 3405-11 (2008)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50260966
PNG
(3-(2-chloro-4-(2-cyclopropyl-4-methyl-1H-imidazol-...)
Show SMILES Cc1cn(c(n1)C1CC1)-c1ccc(-c2nnc(n2C)C2(CCC2)c2ccc(Cl)cc2)c(Cl)c1
Show InChI InChI=1S/C26H25Cl2N5/c1-16-15-33(23(29-16)17-4-5-17)20-10-11-21(22(28)14-20)24-30-31-25(32(24)2)26(12-3-13-26)18-6-8-19(27)9-7-18/h6-11,14-15,17H,3-5,12-13H2,1-2H3
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta HSD2


Bioorg Med Chem Lett 18: 3405-11 (2008)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50260965
PNG
(3-(2-chloro-4-(2,4-dimethyl-1H-imidazol-1-yl)pheny...)
Show SMILES Cc1cn(c(C)n1)-c1ccc(-c2nnc(n2C)C2(CCC2)c2ccc(Cl)cc2)c(Cl)c1
Show InChI InChI=1S/C24H23Cl2N5/c1-15-14-31(16(2)27-15)19-9-10-20(21(26)13-19)22-28-29-23(30(22)3)24(11-4-12-24)17-5-7-18(25)8-6-17/h5-10,13-14H,4,11-12H2,1-3H3
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta HSD2


Bioorg Med Chem Lett 18: 3405-11 (2008)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50260964
PNG
(3-(2-chloro-4-(2-methyl-1H-imidazol-1-yl)phenyl)-5...)
Show SMILES Cc1nccn1-c1ccc(-c2nnc(n2C)C2(CCC2)c2ccc(Cl)cc2)c(Cl)c1
Show InChI InChI=1S/C23H21Cl2N5/c1-15-26-12-13-30(15)18-8-9-19(20(25)14-18)21-27-28-22(29(21)2)23(10-3-11-23)16-4-6-17(24)7-5-16/h4-9,12-14H,3,10-11H2,1-2H3
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta HSD2


Bioorg Med Chem Lett 18: 3405-11 (2008)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50260938
PNG
(3-(2-chloro-4-(1H-imidazol-1-yl)phenyl)-5-(1-(4-ch...)
Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1Cl)-n1ccnc1
Show InChI InChI=1S/C22H19Cl2N5/c1-28-20(18-8-7-17(13-19(18)24)29-12-11-25-14-29)26-27-21(28)22(9-2-10-22)15-3-5-16(23)6-4-15/h3-8,11-14H,2,9-10H2,1H3
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta HSD2


Bioorg Med Chem Lett 18: 3405-11 (2008)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50260936
PNG
(2-(3-chloro-4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-...)
Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1Cl)-c1ccccn1
Show InChI InChI=1S/C24H20Cl2N4/c1-30-22(19-11-6-16(15-20(19)26)21-5-2-3-14-27-21)28-29-23(30)24(12-4-13-24)17-7-9-18(25)10-8-17/h2-3,5-11,14-15H,4,12-13H2,1H3
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n/an/a>4.00E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta HSD2


Bioorg Med Chem Lett 18: 3405-11 (2008)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50260910
PNG
(4-(3-chloro-4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-...)
Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1Cl)-c1ccncc1
Show InChI InChI=1S/C24H20Cl2N4/c1-30-22(20-8-3-17(15-21(20)26)16-9-13-27-14-10-16)28-29-23(30)24(11-2-12-24)18-4-6-19(25)7-5-18/h3-10,13-15H,2,11-12H2,1H3
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta HSD2


Bioorg Med Chem Lett 18: 3405-11 (2008)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50260908
PNG
(3-(3-chloro-4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-...)
Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1Cl)-c1cccnc1
Show InChI InChI=1S/C24H20Cl2N4/c1-30-22(20-10-5-16(14-21(20)26)17-4-2-13-27-15-17)28-29-23(30)24(11-3-12-24)18-6-8-19(25)9-7-18/h2,4-10,13-15H,3,11-12H2,1H3
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta HSD2


Bioorg Med Chem Lett 18: 3405-11 (2008)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50260882
PNG
(3-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-5-(4-(th...)
Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1)-c1nccs1
Show InChI InChI=1S/C22H19ClN4S/c1-27-19(15-3-5-16(6-4-15)20-24-13-14-28-20)25-26-21(27)22(11-2-12-22)17-7-9-18(23)10-8-17/h3-10,13-14H,2,11-12H2,1H3
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta HSD2


Bioorg Med Chem Lett 18: 3405-11 (2008)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50260881
PNG
(3-(4-(1H-pyrrol-1-yl)phenyl)-5-(1-(4-chlorophenyl)...)
Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1)-n1cccc1
Show InChI InChI=1S/C23H21ClN4/c1-27-21(17-5-11-20(12-6-17)28-15-2-3-16-28)25-26-22(27)23(13-4-14-23)18-7-9-19(24)10-8-18/h2-3,5-12,15-16H,4,13-14H2,1H3
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta HSD2


Bioorg Med Chem Lett 18: 3405-11 (2008)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50260879
PNG
(3-(4-(1H-imidazol-1-yl)phenyl)-5-(1-(4-chloropheny...)
Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1)-n1ccnc1
Show InChI InChI=1S/C22H20ClN5/c1-27-20(16-3-9-19(10-4-16)28-14-13-24-15-28)25-26-21(27)22(11-2-12-22)17-5-7-18(23)8-6-17/h3-10,13-15H,2,11-12H2,1H3
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta HSD2


Bioorg Med Chem Lett 18: 3405-11 (2008)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50260878
PNG
(3-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-5-(4-phe...)
Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C25H22ClN3O/c1-29-23(18-8-14-22(15-9-18)30-21-6-3-2-4-7-21)27-28-24(29)25(16-5-17-25)19-10-12-20(26)13-11-19/h2-4,6-15H,5,16-17H2,1H3
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta HSD2


Bioorg Med Chem Lett 18: 3405-11 (2008)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50260825
PNG
(3-(4-tert-butylphenyl)-5-(1-(4-chlorophenyl)cyclob...)
Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1)C(C)(C)C
Show InChI InChI=1S/C23H26ClN3/c1-22(2,3)17-8-6-16(7-9-17)20-25-26-21(27(20)4)23(14-5-15-23)18-10-12-19(24)13-11-18/h6-13H,5,14-15H2,1-4H3
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta HSD2


Bioorg Med Chem Lett 18: 3405-11 (2008)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50260824
PNG
(3-(4-benzylphenyl)-5-(1-(4-chlorophenyl)cyclobutyl...)
Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(Cc2ccccc2)cc1
Show InChI InChI=1S/C26H24ClN3/c1-30-24(21-10-8-20(9-11-21)18-19-6-3-2-4-7-19)28-29-25(30)26(16-5-17-26)22-12-14-23(27)15-13-22/h2-4,6-15H,5,16-18H2,1H3
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta HSD2


Bioorg Med Chem Lett 18: 3405-11 (2008)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50260823
PNG
(3-[1-(4-Chloro-phenyl)-cyclobutyl]-5-(4'-fluoro-bi...)
Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1)-c1ccc(F)cc1
Show InChI InChI=1S/C25H21ClFN3/c1-30-23(19-5-3-17(4-6-19)18-7-13-22(27)14-8-18)28-29-24(30)25(15-2-16-25)20-9-11-21(26)12-10-20/h3-14H,2,15-16H2,1H3
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta HSD2


Bioorg Med Chem Lett 18: 3405-11 (2008)

More data for this
Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)


(Mus musculus (mouse))
BDBM50260822
PNG
(3-Biphenyl-3-yl-5-[1-(4-chloro-phenyl)-cyclobutyl]...)
Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C25H22ClN3/c1-29-23(20-10-5-9-19(17-20)18-7-3-2-4-8-18)27-28-24(29)25(15-6-16-25)21-11-13-22(26)14-12-21/h2-5,7-14,17H,6,15-16H2,1H3
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta HSD2


Bioorg Med Chem Lett 18: 3405-11 (2008)

More data for this
Ligand-Target Pair
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