Found 161 hits of affinity data for UniProtKB/TrEMBL: P31751Target (Institution) | Ligand | Target Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | pH | Temp °C |
Protein kinase B (Akt 2)
Homo sapiens (human) | A-443654
 (5-indazolyl pyridine 3 | 5-{5-[(2S)-2-amino-3-(1H-...) | B.MOAD GoogleScholar MMDB PDB
| B.MOAD CSLS MMDB PC cid PC sid PDB
| B.MOAD MMDB PDB PubMed
| n/a | n/a | 0.5 | n/a | n/a | 7.2 | 22 |
Astex
|
J Mol Biol. 367: 882-94 (2007)
 |
Protein kinase B (Akt 2)
Homo sapiens (human) | oxadiazole-containing compound, 3d
 (4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-[(3S)-3-amin...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| PC cid PC sid
| PubMed
| n/a | n/a | 4.0 | n/a | n/a | 7.5 | 22 |
GlaxoSmithKline
|
J Med Chem. 51: 5663-79 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | Isoquinoline-pyridine, 10a
 (6-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]-2-chl...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 5.0 | n/a | n/a | 7.5 | 22 |
Abbott Laboratories
|
Bioorg Med Chem Lett. 16: 3150-5 (2006)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | Isoquinoline-pyridine, 10e
 (6-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]-2-eth...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| PC cid PC sid
| PubMed
| n/a | n/a | 5.0 | n/a | n/a | 7.5 | 22 |
Abbott Laboratories
|
Bioorg Med Chem Lett. 16: 3150-5 (2006)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | oxadiazole-containing compound, 14b
 ((2S)-3-[(3-{[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-et...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| PC cid PC sid
| PubMed
| n/a | n/a | 5.0 | n/a | n/a | 7.5 | 22 |
GlaxoSmithKline
|
J Med Chem. 51: 5663-79 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | oxadiazole-containing compound, 14a
 (4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(3-{...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| PC cid PC sid
| PubMed
| n/a | n/a | 6.0 | n/a | n/a | 7.5 | 22 |
GlaxoSmithKline
|
J Med Chem. 51: 5663-79 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | Staurosporine
 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| B.MOAD CHEBI CSLS MMDB PC cid PC sid PDB
| PubMed
| n/a | n/a | 6.5 | n/a | n/a | 7.5 | 22 |
Abbott Laboratories
|
Bioorg Med Chem Lett. 16: 2000-7 (2006)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | pyridine-base inhibitor 13a
 ((2S)-1-(1H-indol-3-yl)-3-(5-isoquinolin-6-ylpyridi...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| B.MOAD CSLS MMDB PC cid PC sid PDB
| PubMed
| n/a | n/a | 6.8 | n/a | n/a | 7.5 | 22 |
Abbott Laboratories
|
Bioorg Med Chem Lett. 16: 2000-7 (2006)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | oxadiazole-containing compound, 3f
 (4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(pip...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| PC cid PC sid
| PubMed
| n/a | n/a | 8.0 | n/a | n/a | 7.5 | 22 |
GlaxoSmithKline
|
J Med Chem. 51: 5663-79 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | oxadiazole-containing compound, 3b
 (4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(pip...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| PC cid PC sid
| PubMed
| n/a | n/a | 8.0 | n/a | n/a | 7.5 | 22 |
GlaxoSmithKline
|
J Med Chem. 51: 5663-79 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | oxadiazole-containing compound, 3a
 (4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(4-aminobuto...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| PC cid PC sid
| PubMed
| n/a | n/a | 9.0 | n/a | n/a | 7.5 | 22 |
GlaxoSmithKline
|
J Med Chem. 51: 5663-79 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | 6-phenylpurine compound 16
 ((4-chlorophenyl)[4-(9H-purin-6-yl)phenyl]methanami...) | B.MOAD GoogleScholar MMDB PDB
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 9.0 | n/a | n/a | 7.2 | 22 |
Astex
|
J Med Chem. 50: 2289-92 (2007)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | 6-phenylpurine compound 18
 (2-(4-chlorophenyl)-N-methyl-2-[4-(9H-purin-6-yl)ph...) | B.MOAD GoogleScholar MMDB PDB
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 10.0 | n/a | n/a | 7.2 | 22 |
Astex
|
J Med Chem. 50: 2289-92 (2007)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | GSK690693
 (4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| MMDB PC cid PC sid PDB
| PDB PubMed
| n/a | n/a | 13.0 | n/a | n/a | 7.5 | 22 |
GlaxoSmithKline
|
J Med Chem. 51: 5663-79 (2008)
 |
Protein kinase B (Akt 2)
Homo sapiens (human) | oxadiazole-containing compound, 3e
 (4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(pyr...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| PC cid PC sid
| PubMed
| n/a | n/a | 13.0 | n/a | n/a | 7.5 | 22 |
GlaxoSmithKline
|
J Med Chem. 51: 5663-79 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | pyrazole-based inhibitor 9
 (4-(4-chlorophenyl)-4-[4-(1H-pyrazol-4-yl)phenyl]pi...) | B.MOAD GoogleScholar MMDB PDB
| B.MOAD CSLS MMDB PC cid PC sid PDB
| B.MOAD MMDB PDB PubMed
| n/a | n/a | 18.0 | n/a | n/a | 7.2 | 22 |
Astex
|
J Med Chem. 50: 2293-2296 (2007)
 |
Protein kinase B (Akt 2)
Homo sapiens (human) | 6-phenylpurine compound 20
 (6-{4-[4-(4-chlorophenyl)piperidin-4-yl]phenyl}-9H-...) | B.MOAD GoogleScholar MMDB PDB
| B.MOAD CSLS MMDB PC cid PC sid PDB
| PubMed
| n/a | n/a | 20.0 | n/a | n/a | 7.2 | 22 |
Astex
|
J Med Chem. 50: 2289-92 (2007)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | oxadiazole-containing compound, 3c
 (4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(2-aminoetho...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| PC cid PC sid
| PubMed
| n/a | n/a | 20.0 | n/a | n/a | 7.5 | 22 |
GlaxoSmithKline
|
J Med Chem. 51: 5663-79 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | Isoquinoline-pyridine, 10y
 (6-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 21.0 | n/a | n/a | 7.5 | 22 |
Abbott Laboratories
|
Bioorg Med Chem Lett. 16: 3150-5 (2006)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | 2,3,5-trisubstituted pyridine, 10c
 (5-{5-phenyl-6-[4-({4-[5-(pyridin-2-yl)-1H-1,2,4-tr...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 22.0 | n/a | n/a | 7.5 | 22 |
Merck Research Laboratories
|
Bioorg Med Chem Lett. 18: 2194-7 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | 2,3,5-trisubstituted pyridine, 10f
 (5-(6-{4-[(4-{4-amino-1H-pyrazolo[3,4-d]pyrimidin-1...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 22.0 | n/a | n/a | 7.5 | 22 |
Merck Research Laboratories
|
Bioorg Med Chem Lett. 18: 2194-7 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | Pyridopyrimidine, 13i
 (2-{5-[1-({4-[2-(methylsulfanyl)-6-phenylpyrido[2,3...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 26.0 | n/a | n/a | 7.5 | 22 |
Merck Research Laboratories
|
Bioorg Med Chem Lett. 18: 1274-9 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | 2,3,5-trisubstituted pyridine, 10b
 (5-{5-phenyl-6-[4-({4-[5-(pyridin-2-yl)-1H-pyrazol-...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 28.0 | n/a | n/a | 7.5 | 22 |
Merck Research Laboratories
|
Bioorg Med Chem Lett. 18: 2194-7 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | 2,3,5-trisubstituted pyridine, 10h
 (3-[({4-[5-(5-amino-1,3,4-thiadiazol-2-yl)-3-phenyl...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 30.0 | n/a | n/a | 7.5 | 22 |
Merck Research Laboratories
|
Bioorg Med Chem Lett. 18: 2194-7 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | pyrazole-based inhibitor 8
 (2-(4-chlorophenyl)-2-[4-(1H-pyrazol-4-yl)phenyl]et...) | B.MOAD GoogleScholar MMDB PDB
| CSLS PC cid PC sid PDB
| PubMed
| n/a | n/a | 31.0 | n/a | n/a | 7.2 | 22 |
Astex
|
J Med Chem. 50: 2293-2296 (2007)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | pyrazole-based inhibitor 8a
 ((2R)-2-(4-chlorophenyl)-2-[4-(1H-pyrazol-4-yl)phen...) | B.MOAD GoogleScholar MMDB PDB
| B.MOAD CSLS MMDB PC cid PC sid PDB
| PubMed
| n/a | n/a | 34.0 | n/a | n/a | 7.2 | 22 |
Astex
|
J Med Chem. 50: 2293-2296 (2007)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | Pyridopyrimidine, 14c
 (6-phenyl-7-[4-({4-[5-(pyridin-2-yl)-4H-1,2,4-triaz...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 35.0 | n/a | n/a | 7.5 | 22 |
Merck Research Laboratories
|
Bioorg Med Chem Lett. 18: 1274-9 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | 2,3,5-trisubstituted pyridine, 10a
 (5-{5-phenyl-6-[4-({4-[5-(pyridin-4-yl)-1H-pyrazol-...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 38.0 | n/a | n/a | 7.5 | 22 |
Merck Research Laboratories
|
Bioorg Med Chem Lett. 18: 2194-7 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | Pyridopyrimidine, 11
 (1-[1-({4-[2-(methylsulfanyl)-6-phenylpyrido[2,3-d]...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 44.0 | n/a | n/a | 7.5 | 22 |
Merck Research Laboratories
|
Bioorg Med Chem Lett. 18: 1274-9 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | 2,3,5-trisubstituted pyridine, 10e
 (5-{5-phenyl-6-[4-({4-[4-(pyrazin-2-yl)-1H-pyrazol-...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 51.0 | n/a | n/a | 7.5 | 22 |
Merck Research Laboratories
|
Bioorg Med Chem Lett. 18: 2194-7 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | Pyridopyrimidine, 13h
 (4-{3-[1-({4-[2-(methylsulfanyl)-6-phenylpyrido[2,3...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 57.0 | n/a | n/a | 7.5 | 22 |
Merck Research Laboratories
|
Bioorg Med Chem Lett. 18: 1274-9 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | Pyridopyrimidine, 14b
 (6-phenyl-7-[4-({4-[5-(pyridin-2-yl)-4H-1,2,4-triaz...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 59.0 | n/a | n/a | 7.5 | 22 |
Merck Research Laboratories
|
Bioorg Med Chem Lett. 18: 1274-9 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | 2,3,5-trisubstituted pyridine, 13c
 (1-[1-({4-[3-phenyl-5-(pyrimidin-2-yl)pyridin-2-yl]...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 62.0 | n/a | n/a | 7.5 | 22 |
Merck Research Laboratories
|
Bioorg Med Chem Lett. 18: 2194-7 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | 2,3,5-trisubstituted pyridine, 13b
 (1-[1-({4-[3-phenyl-5-(1,3-thiazol-2-yl)pyridin-2-y...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| PC cid PC sid
| PubMed
| n/a | n/a | 64.0 | n/a | n/a | 7.5 | 22 |
Merck Research Laboratories
|
Bioorg Med Chem Lett. 18: 2194-7 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | quinoxaline 16c
 (1-[1-({4-[3-phenyl-6-(2H-1,2,3,4-tetrazol-5-yl)qui...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 65.0 | n/a | n/a | 7.5 | 22 |
Merck Research Laboratories
|
Bioorg Med Chem Lett. 15: 761-4 (2005)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | 2,3,5-trisubstituted pyridine, 10g
 (1-[1-({4-[5-(5-amino-1,3,4-thiadiazol-2-yl)-3-phen...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 73.0 | n/a | n/a | 7.5 | 22 |
Merck Research Laboratories
|
Bioorg Med Chem Lett. 18: 2194-7 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | 2,3,5-trisubstituted pyridine, 10d
 (5-{5-phenyl-6-[4-({4-[4-(pyridin-2-yl)-1H-pyrazol-...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 90.0 | n/a | n/a | 7.5 | 22 |
Merck Research Laboratories
|
Bioorg Med Chem Lett. 18: 2194-7 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | Pyridopyrimidine, 12l
 (1-(2-aminophenyl)-3-[({4-[2-(methylsulfanyl)-6-phe...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| CHEBI CSLS PC cid PC sid
| PubMed
| n/a | n/a | 90.0 | n/a | n/a | 7.5 | 22 |
Merck Research Laboratories
|
Bioorg Med Chem Lett. 18: 1274-9 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | Pyridopyrimidine, 14d
 (N-methyl-6-phenyl-7-[4-({4-[5-(pyridin-2-yl)-4H-1,...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| CHEBI CSLS PC cid PC sid
| PubMed
| n/a | n/a | 94.4 | n/a | n/a | 7.5 | 22 |
Merck Research Laboratories
|
Bioorg Med Chem Lett. 18: 1274-9 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | Pyridopyrimidine, 2
 (7-{4-[(4-{4-amino-1H-pyrazolo[3,4-d]pyrimidin-1-yl...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 99.0 | n/a | n/a | 7.5 | 22 |
Merck Research Laboratories
|
Bioorg Med Chem Lett. 18: 1274-9 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | 2,3,5-trisubstituted pyridine, 13e
 (1-[1-({4-[3-phenyl-5-(1H-1,2,4-triazol-3-yl)pyridi...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 101.0 | n/a | n/a | 7.5 | 22 |
Merck Research Laboratories
|
Bioorg Med Chem Lett. 18: 2194-7 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | 2,3,5-trisubstituted pyridine, 3
 (9-[1-({4-[3-phenyl-5-(1H-1,2,3,4-tetrazol-5-yl)pyr...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 105.0 | n/a | n/a | 7.5 | 22 |
Merck Research Laboratories
|
Bioorg Med Chem Lett. 18: 2194-7 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | Pyridopyrimidine, 14a
 (2-(5-{1-[(4-{2-methoxy-6-phenylpyrido[2,3-d]pyrimi...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 107.2 | n/a | n/a | 7.5 | 22 |
Merck Research Laboratories
|
Bioorg Med Chem Lett. 18: 1274-9 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | 2,3,5-trisubstituted pyridine, 13d
 (1-[1-({4-[5-(1,2,4-oxadiazol-3-yl)-3-phenylpyridin...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 121.0 | n/a | n/a | 7.5 | 22 |
Merck Research Laboratories
|
Bioorg Med Chem Lett. 18: 2194-7 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | quinoxaline 16d
 (1-[1-({4-[3-phenyl-7-(2H-1,2,3,4-tetrazol-5-yl)qui...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 144.0 | n/a | n/a | 7.5 | 22 |
Merck Research Laboratories
|
Bioorg Med Chem Lett. 15: 761-4 (2005)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | tetrazolylypyridine 8a
 (1-[1-({4-[3-phenyl-5-(1H-1,2,3,4-tetrazol-5-yl)pyr...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 157.0 | n/a | n/a | 7.5 | 22 |
Merck Research Laboratories
|
Bioorg Med Chem Lett. 15: 905-9 (2005)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | pyrazole-based inhibitor 7
 (4-phenyl-4-[4-(1H-pyrazol-4-yl)phenyl]piperidine) | B.MOAD GoogleScholar MMDB PDB
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 200.0 | n/a | n/a | 7.2 | 22 |
Astex
|
J Med Chem. 50: 2293-2296 (2007)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | oxadiazole-containing compound, 7
 (4-[1-ethyl-7-(piperidin-4-ylmethoxy)-1H-imidazo[4,...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 204.0 | n/a | n/a | 7.5 | 22 |
GlaxoSmithKline
|
J Med Chem. 51: 5663-79 (2008)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | imidazoquinoxaline 16h
 (1-{1-[(4-{7-phenyl-1H-imidazo[4,5-g]quinoxalin-6-y...) | B.MOAD GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 210.0 | n/a | n/a | 7.5 | 22 |
Merck Research Laboratories
|
Bioorg Med Chem Lett. 15: 761-4 (2005)
|
Protein kinase B (Akt 2)
Homo sapiens (human) | isoquinoline-5-sulfonamide 10
 (Isoquinoline-5-sulfonic acid (2-(2-(3,4-dichlorobe...) | B.MOAD GoogleScholar MMDB PDB
| CSLS PC cid PC sid
| PubMed
| n/a | n/a | 210.0 | n/a | n/a | 7.2 | 22 |
UK Centre for Cancer Therapeutics
|
Bioorg Med Chem. 14: 1255-73 (2006)
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