Compile Data Set for Download or QSAR
maximum 50k data
Found 1954 of ic50 data for polymerid = 1662
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50512318(CHEMBL4546504)
Affinity DataIC50:  0.0320nMAssay Description:Inhibition of recombinant human full length His-tagged JNK1 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50059652(CHEMBL3220502)
Affinity DataIC50:  0.240nMAssay Description:Inhibition of JNK1 (unknown origin) by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50352631(CHEMBL1822313)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of JNK1 using ATF2 substrate by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50059665(CHEMBL3393600)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of JNK1 (unknown origin) by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50352631(CHEMBL1822313)
Affinity DataIC50:  0.900nMAssay Description:Displacement of biotin-RPKRPTTLNLF from GST tagged JNK1 using ATF2 substrate by dissociation enhanced lanthanide fluoro-immuno assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50352621(CHEMBL1822152)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant JNK1 using ser73 of c-jun as substrate preincubated for 15 mins measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50059649(CHEMBL3220493)
Affinity DataIC50:  1nMAssay Description:Inhibition of JNK1 (unknown origin) by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50352624(CHEMBL1822305 | US9796706, Compound 139)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant JNK1 using ser73 of c-jun as substrate preincubated for 15 mins measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM100437(US8501732, I-1)
Affinity DataIC50:  1nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50352620(CHEMBL1822151)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant JNK1 using ser73 of c-jun as substrate preincubated for 15 mins measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50578360(CHEMBL4849353)
Affinity DataIC50:  1nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM86633(JNK-IN-8)
Affinity DataIC50:  1nMAssay Description:Inhibition of JNK1 (unknown origin) after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50578357(CHEMBL4856984)
Affinity DataIC50:  1nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM86636(JNK-IN-11)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of JNK1 (unknown origin) after 1 hr incubationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM86636(JNK-IN-11)
Affinity DataIC50:  1.34nMAssay Description:The binding results were confirmed by measuring IC50 for the inhibition of JNK kinase activity by using Z'-LYTE assay format.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM86632(JNK-IN-7)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of JNK1 (unknown origin) after 1 hr incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM86632(JNK-IN-7)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of wild-type human full length JNK1 (M1 to Q384 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM86632(JNK-IN-7)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of JNK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM86632(JNK-IN-7)
Affinity DataIC50:  1.54nMAssay Description:The binding results were confirmed by measuring IC50 for the inhibition of JNK kinase activity by using Z'-LYTE assay format.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50578367(CHEMBL4864618)
Affinity DataIC50:  2nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50578347(CHEMBL4853125)
Affinity DataIC50:  2nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50578358(CHEMBL4878370)
Affinity DataIC50:  2nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50352615(CHEMBL1822146)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant JNK1 using ser73 of c-jun as substrate preincubated for 15 mins measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50352618(CHEMBL1822149)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant JNK1 using ser73 of c-jun as substrate preincubated for 15 mins measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM102578(US8536172, I-27)
Affinity DataIC50:  2nMpH: 7.5Assay Description:JNK activity was measured by phosphorylation of GST-ATF2 (19-96) with [gamma-33P] ATP.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50352628(CHEMBL1822309 | US9796706, Compound 136)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant JNK1 using ser73 of c-jun as substrate preincubated for 15 mins measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM16016(CHEMBL437747 | N-cyclohexyl-4-[4-(3,4-dichlorophen...)
Affinity DataIC50:  2nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM86630(JNK-IN-5)
Affinity DataIC50:  2.11nMAssay Description:The binding results were confirmed by measuring IC50 for the inhibition of JNK kinase activity by using Z'-LYTE assay format.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM102593(US8536172, I-42)
Affinity DataIC50:  2.40nMpH: 7.5Assay Description:JNK activity was measured by phosphorylation of GST-ATF2 (19-96) with [gamma-33P] ATP.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50578346(CHEMBL4847078)
Affinity DataIC50:  3nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM102557(US8536172, I-6)
Affinity DataIC50:  3nMpH: 7.5Assay Description:JNK activity was measured by phosphorylation of GST-ATF2 (19-96) with [gamma-33P] ATP.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM102563(US8536172, I-12)
Affinity DataIC50:  3nMAssay Description:Inhibition of human JNK1alpha1 using GST-tagged ATF2 as substrate preincubated for 10 mins prior to substrate addition measured after 30 mins by micr...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM102557(US8536172, I-6)
Affinity DataIC50:  3nMAssay Description:Inhibition of human JNK1alpha1 using GST-tagged ATF2 as substrate preincubated for 10 mins prior to substrate addition measured after 30 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50578346(CHEMBL4847078)
Affinity DataIC50:  3nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50578365(CHEMBL4853525)
Affinity DataIC50:  3nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50578366(CHEMBL4845965)
Affinity DataIC50:  3nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM102565(US8536172, I-14)
Affinity DataIC50:  3nMpH: 7.5Assay Description:JNK activity was measured by phosphorylation of GST-ATF2 (19-96) with [gamma-33P] ATP.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50059650(CHEMBL3220495)
Affinity DataIC50:  3nMAssay Description:Inhibition of JNK1 (unknown origin) by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50352614(CHEMBL1822145)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant JNK1 using ser73 of c-jun as substrate preincubated for 15 mins measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50352613(CHEMBL1822144)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant JNK1 using ser73 of c-jun as substrate preincubated for 15 mins measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM102563(US8536172, I-12)
Affinity DataIC50:  3.10nMpH: 7.5Assay Description:JNK activity was measured by phosphorylation of GST-ATF2 (19-96) with [gamma-33P] ATP.More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50373218(CHEMBL260429)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM102602(US8536172, I-51)
Affinity DataIC50:  3.60nMpH: 7.5Assay Description:JNK activity was measured by phosphorylation of GST-ATF2 (19-96) with [gamma-33P] ATP.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM102573(US8536172, I-22)
Affinity DataIC50:  3.60nMpH: 7.5Assay Description:JNK activity was measured by phosphorylation of GST-ATF2 (19-96) with [gamma-33P] ATP.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM102566(US8536172, I-15)
Affinity DataIC50:  3.60nMpH: 7.5Assay Description:JNK activity was measured by phosphorylation of GST-ATF2 (19-96) with [gamma-33P] ATP.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM102577(US8536172, I-26)
Affinity DataIC50:  3.70nMpH: 7.5Assay Description:JNK activity was measured by phosphorylation of GST-ATF2 (19-96) with [gamma-33P] ATP.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM100550(US8501732, I-110)
Affinity DataIC50:  4nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM100549(US8501732, I-109)
Affinity DataIC50:  4nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM100445(US8501732, I-9)
Affinity DataIC50:  4nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50352609(CHEMBL1822140)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant JNK1 using ser73 of c-jun as substrate preincubated for 15 mins measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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