Compile Data Set for Download or QSAR
maximum 50k data
Found 38 of ic50 data for polymerid = 1730
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM16499((2S)-2-[(2S,3S)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxir...)
Affinity DataIC50:  23nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM16500((2S)-2-[(2S,3S)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxir...)
Affinity DataIC50:  24nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM16502((2S)-1-[(2S,3S)-2-{[(2S,3S)-3-(benzylcarbamoyl)oxi...)
Affinity DataIC50:  29nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM16509((2S)-1-[(2S,3S)-3-methyl-2-{[(2S,3S)-3-(propylcarb...)
Affinity DataIC50:  38nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM16510((2S,3S)-3-[[(1S)-1-(isoamylcarbamoyl)-3-methyl-but...)
Affinity DataIC50:  40nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM50046899(2-Acetylamino-4-methyl-pentanoic acid [1-(5-amino-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM16508((2S)-1-[(2S,3S)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxir...)
Affinity DataIC50:  120nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)
Affinity DataIC50:  310nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM16501((2S)-2-[(2S,3R)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxir...)
Affinity DataIC50:  410nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM50046896(2-Acetylamino-4-methyl-pentanoic acid [1-(1-formyl...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM50046887(2-(2-Acetylamino-3-phenyl-propionylamino)-4-methyl...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM50046888(2-(2-Acetylamino-3-methyl-butyrylamino)-4-methyl-p...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM50484453(Shishicrellastatin A)
Affinity DataIC50:  6.79E+3nMAssay Description:Inhibition of bovine cathepsin B after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM50484452(Shishicrellastatin B)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of bovine cathepsin B after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM16504(CA inhibitor 7 | CA073 | PrNH-tES-Ile-Pro-OBzl | b...)
Affinity DataIC50:  9.10E+3nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM50047352(CHEMBL3314610)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of bovine spleen cathepsin B using Z-Arg-Arg-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM50046885(2-(2-Acetylamino-3-phenyl-propionylamino)-N-(1-for...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM50046890(2-Acetylamino-4-methyl-pentanoic acid [1-(5-amino-...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM50047353(CHEMBL3314607)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of bovine spleen cathepsin B using Z-Arg-Arg-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM16506((2S)-1-(2-{[(2S,3S)-3-(ethoxycarbonyl)oxiran-2-yl]...)
Affinity DataIC50:  1.53E+4nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM50368642(ACETYLPEPSTATIN)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of bovine spleen cathepsin B using Z-Arg-Arg-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM50046900(2-(2-Acetylamino-3-phenyl-propionylamino)-4-methyl...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM50046891(2-(2-Acetylamino-4-methyl-pentanoylamino)-3-methyl...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM50046898(2-Acetylamino-4-methyl-pentanoic acid [1-(5-amino-...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM16497((2S,3S)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxiran-2-yl]...)
Affinity DataIC50:  2.40E+4nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM50047355(CHEMBL3314608)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of bovine spleen cathepsin B using Z-Arg-Arg-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM50047354(CHEMBL3314609)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of bovine spleen cathepsin B using Z-Arg-Arg-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM50046895(2-Acetylamino-3-methyl-pentanoic acid [1-(5-amino-...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM50047351(CHEBI:7988 | CHEMBL3314611)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of bovine spleen cathepsin B using Z-Arg-Arg-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM16505(BzlNH-tES-Ile-Pro-OBzl | CA inhibitor 8 | CA077 | ...)
Affinity DataIC50:  4.60E+4nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM50046894(2-(2-Acetylamino-3-methyl-butyrylamino)-4-methyl-p...)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM50046892(2-Acetylamino-4-methyl-pentanoic acid [1-(1-formyl...)
Affinity DataIC50:  6.60E+4nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM16503(CA inhibitor 6 | CA074Me | PrNH-tES-Ile-Pro-OMe | ...)
Affinity DataIC50:  6.80E+4nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM50046893(2-[2-Acetylamino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50:  7.80E+4nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM50046889(2-Acetylamino-4-methyl-pentanoic acid [1-(1-formyl...)
Affinity DataIC50:  1.30E+5nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM50147766(CHEMBL3765121)
Affinity DataIC50:  1.70E+5nMAssay Description:Inhibition of bovine spleen cathepsin B using Z-Arg-Arg-MCA as substrate incubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM50224807(CHEMBL400366 | cyclo(Pro-Gly-Leu-Val-Met-Phe-Gly-V...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of bovine Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM50147767(CHEMBL3765089)
Affinity DataIC50:  5.00E+5nMAssay Description:Inhibition of bovine spleen cathepsin B using Z-Arg-Arg-MCA as substrate incubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed