Compile Data Set for Download or QSAR
(2D       Computed 3D by Vconf -m prep )

Data curated solely by BindingDB

Found 9 hits of affinity data for UniProtKB/TrEMBL: P42330

Target (Institution)	Ligand	Target Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	pH	Temp °C
17-beta-Hydroxysteroid Dehydrogenase 5 (17-beta-HSD5, AKR1C3) Homo sapiens (human)	EM-1404 ((2R,15'S)-5,5,15'-trimethyl-6-oxospiro[oxane-2,14'...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid PDB	PDB PubMed	6.900	-48.45	n/a	n/a	n/a	7.5	37
CHUL					J Biol Chem. 282: 8368-79 (2007)
17-beta-Hydroxysteroid Dehydrogenase 5 (17-beta-HSD5, AKR1C3) Homo sapiens (human)	Flufenamic acid (2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	B.MOAD CHEBI CSLS DrugBank KEGG MMDB PC cid PC sid PDB	B.MOAD DrugBank MMDB PDB PubMed	140.0	-39.77	n/a	n/a	n/a	7	30
The University of Birmingham					Cancer Res. 64: 1802-10 (2004)
17-beta-Hydroxysteroid Dehydrogenase 5 (17-beta-HSD5, AKR1C3) Homo sapiens (human)	Indomethacin (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS DrugBank KEGG MMDB PC cid PC sid PDB	PDB PubMed	270.0	-38.12	n/a	n/a	n/a	7	30
The University of Birmingham					Cancer Res. 64: 1802-10 (2004)
17-beta-Hydroxysteroid Dehydrogenase 5 (17-beta-HSD5, AKR1C3) Homo sapiens (human)	Indomethacin (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS DrugBank KEGG MMDB PC cid PC sid PDB	PDB PubMed	2100	-32.95	n/a	n/a	n/a	7	30
The University of Birmingham					Cancer Res. 64: 1802-10 (2004)
17-beta-Hydroxysteroid Dehydrogenase 5 (17-beta-HSD5, AKR1C3) Homo sapiens (human)	Flufenamic acid (2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	B.MOAD CHEBI CSLS DrugBank KEGG MMDB PC cid PC sid PDB	B.MOAD DrugBank MMDB PDB PubMed	3100	-31.96	n/a	n/a	n/a	7	30
The University of Birmingham					Cancer Res. 64: 1802-10 (2004)
17-beta-Hydroxysteroid Dehydrogenase 5 (17-beta-HSD5, AKR1C3) Homo sapiens (human)	3,5-dichlorosalicylic acid (3,5-dichloro-2-hydroxybenzoic acid)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS MMDB PC cid PC sid PDB	MMDB PDB PubMed	94000	-22.98	n/a	n/a	n/a	7.4	25
Monash University					J Med Chem. 51: 4844-8 (2008)
17-beta-Hydroxysteroid Dehydrogenase 5 (17-beta-HSD5, AKR1C3) Homo sapiens (human)	EM-1404 ((2R,15'S)-5,5,15'-trimethyl-6-oxospiro[oxane-2,14'...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid PDB	PDB PubMed	n/a	n/a	3.2	n/a	n/a	6	22
CHUL					J Biol Chem. 282: 8368-79 (2007)
17-beta-Hydroxysteroid Dehydrogenase 5 (17-beta-HSD5, AKR1C3) Homo sapiens (human)	EM-1424 ((2R,15'S)-5'-(2-methoxyethoxy)-5,5,15'-trimethyl-6...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	9.5	n/a	n/a	6	22
CHUL					J Biol Chem. 282: 8368-79 (2007)
17-beta-Hydroxysteroid Dehydrogenase 5 (17-beta-HSD5, AKR1C3) Homo sapiens (human)	EM-1396 ((2R,15'S)-5'-(2-methoxyethoxy)-5,5,15'-trimethyl-6...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	n/a	n/a	13.0	n/a	n/a	6	22
CHUL					J Biol Chem. 282: 8368-79 (2007)

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