Compile Data Set for Download or QSAR
(2D       Computed 3D by Vconf -m prep )

Data curated solely by BindingDB

Found 132 hits of affinity data for UniProtKB/TrEMBL: P00374

Target (Institution)	Ligand	Target Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	pH	Temp °C
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	1,8-naphthalein derivative, 13 (4-(3-bromo-4-hydroxyphenyl)-4-(4-hydroxyphenyl)-3-...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	3400	-31.21	n/a	n/a	n/a	7	25
UNIMORE					J Med Chem. 49: 5958-68 (2006)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	1,2-naphthalein derivative, 3 (3,3-bis(4-hydroxy-3-iodophenyl)-4-oxatricyclo[7.4....)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	3900	-30.87	n/a	n/a	n/a	7	25
UNIMORE					J Med Chem. 49: 5958-68 (2006)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	A156 (1,8-naphthalein derivative, 10 | 4,4-bis(3-chloro-...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	B.MOAD CHEBI CSLS MMDB PC cid PC sid PDB	PubMed	5200	-30.15	n/a	n/a	n/a	7	25
UNIMORE					J Med Chem. 49: 5958-68 (2006)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	1,8-naphthalein derivative, 15 (4,4-bis(3,5-dibromo-4-hydroxyphenyl)-3-oxatricyclo...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	9500	-28.66	n/a	n/a	n/a	7	25
UNIMORE					J Med Chem. 49: 5958-68 (2006)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	1,8-naphthalein derivative, 18 (8-chloro-4,4-bis(3-fluoro-4-hydroxyphenyl)-3-oxatr...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	12000	-28.08	n/a	n/a	n/a	7	25
UNIMORE					J Med Chem. 49: 5958-68 (2006)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	1,8-naphthalein derivative, 16 (4,4-bis(3-bromo-4-hydroxyphenyl)-8-chloro-3-oxatri...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	13000	-27.88	n/a	n/a	n/a	7	25
UNIMORE					J Med Chem. 49: 5958-68 (2006)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	1,2-naphthalein derivative, 6 (3,3-bis[4-hydroxy-2-methyl-5-(propan-2-yl)phenyl]-...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	13000	-27.88	n/a	n/a	n/a	7	25
UNIMORE					J Med Chem. 49: 5958-68 (2006)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	1,8-naphthalein derivative, 14 (4,4-bis(3-bromo-4-hydroxyphenyl)-3-oxatricyclo[7.3...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	15000	-27.53	n/a	n/a	n/a	7	25
UNIMORE					J Med Chem. 49: 5958-68 (2006)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	1,8-naphthalein derivative, 12 (4,4-bis(3,5-dichloro-4-hydroxyphenyl)-3-oxatricycl...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	28000	-25.98	n/a	n/a	n/a	7	25
UNIMORE					J Med Chem. 49: 5958-68 (2006)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	1,2-naphthalein derivative, 4 (3,3-bis(3-bromo-4-hydroxyphenyl)-4-oxatricyclo[7.4...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	33000	-25.57	n/a	n/a	n/a	7	25
UNIMORE					J Med Chem. 49: 5958-68 (2006)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	1,2-naphthalein derivative, 2 (5,5-bis(4-hydroxyphenyl)-4-oxatricyclo[7.4.0.0^{2,...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	35000	-25.43	n/a	n/a	n/a	7	25
UNIMORE					J Med Chem. 49: 5958-68 (2006)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	1,2-naphthalein derivative, 7 (5,5-bis(3-chloro-4-hydroxyphenyl)-4-oxatricyclo[7....)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	35000	-25.43	n/a	n/a	n/a	7	25
UNIMORE					J Med Chem. 49: 5958-68 (2006)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	1,8-naphthalein derivative, 17 (4,4-bis(3-fluoro-4-hydroxyphenyl)-3-oxatricyclo[7....)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS PC cid PC sid	PubMed	42000	-24.98	n/a	n/a	n/a	7	25
UNIMORE					J Med Chem. 49: 5958-68 (2006)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	1,2-naphthalein derivative, 5 (3,3-bis(3,5-dibromo-4-hydroxyphenyl)-4-oxatricyclo...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	69000	-23.75	n/a	n/a	n/a	7	25
UNIMORE					J Med Chem. 49: 5958-68 (2006)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	1,8-naphthalein derivative, 9 (4,4-bis(4-hydroxy-3-iodophenyl)-3-oxatricyclo[7.3....)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	94000	-22.98	n/a	n/a	n/a	7	25
UNIMORE					J Med Chem. 49: 5958-68 (2006)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	1,2-naphthalein derivative, 8 (5,5-bis(3-fluoro-4-hydroxyphenyl)-4-oxatricyclo[7....)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	109000	-22.61	n/a	n/a	n/a	7	25
UNIMORE					J Med Chem. 49: 5958-68 (2006)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	1,2-naphthalein derivative, 1 (3,3-bis(4-hydroxyphenyl)-4-oxatricyclo[7.4.0.0^{2,...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	110000	-22.59	n/a	n/a	n/a	7	25
UNIMORE					J Med Chem. 49: 5958-68 (2006)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	GW345 (1,3-DIAMINO-7-(1-ETHYEPROPYE)-7H-PYRRALO-[3,2-F]QU...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	B.MOAD CHEBI CSLS MMDB PC cid PC sid PDB	PubMed	n/a	n/a	6.6	n/a	n/a	7	30
GSK					J Med Chem. 44: 2928-32 (2001)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	2,4-diaminopyrimidine-based antagonist, 4c (6-ethyl-5-(4-{[(4-methanesulfonylphenyl)methyl]ami...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS PC cid PC sid	PubMed	n/a	n/a	<10.0	n/a	n/a	7.3	37
Abbott Laboratories					J Med Chem. 49: 4459-69 (2006)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	thieno[2,3-d]pyrimidine deriv., 2	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	MMDB PC cid PC sid PDB	MMDB PDB PubMed	n/a	n/a	19.0	n/a	n/a	7.4	30
Duquesne University					J Med Chem. 52: 4892-902 (2009)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	thieno[2,3-d]pyrimidine deriv., 1	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS MMDB PC cid PC sid PDB	MMDB PDB PubMed	n/a	n/a	20.0	n/a	n/a	7.4	30
Duquesne University					J Med Chem. 52: 4892-902 (2009)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	Methotrexate (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	B.MOAD CHEBI CSLS DrugBank KEGG MMDB PC cid PC sid PDB	B.MOAD DrugBank MMDB PDB PubMed	n/a	n/a	20.0	n/a	n/a	7.4	30
Duquesne University					J Med Chem. 51: 68-76 (2008)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	Methotrexate (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	B.MOAD CHEBI CSLS DrugBank KEGG MMDB PC cid PC sid PDB	B.MOAD DrugBank MMDB PDB PubMed	n/a	n/a	20.0	n/a	n/a	7.4	30
Duquesne University					J Med Chem. 52: 4892-902 (2009)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	Methotrexate (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	B.MOAD CHEBI CSLS DrugBank KEGG MMDB PC cid PC sid PDB	B.MOAD DrugBank MMDB PDB PubMed	n/a	n/a	22.0	n/a	12.5	7.4	30
Duquesne University					J Med Chem. 48: 7215-22 (2005)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	Methotrexate (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	B.MOAD CHEBI CSLS DrugBank KEGG MMDB PC cid PC sid PDB	B.MOAD DrugBank MMDB PDB PubMed	n/a	n/a	22.0	n/a	13.3	7.4	30
Duquesne University					J Med Chem. 50: 3046-3053 (2007)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	Methotrexate (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	B.MOAD CHEBI CSLS DrugBank KEGG MMDB PC cid PC sid PDB	B.MOAD DrugBank MMDB PDB PubMed	n/a	n/a	24.3	n/a	n/a	7	30
Oklahoma State University at Stillwater					Antimicrob Agents Chemother. 48: 4643-9 (2004)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	Propargyl inhibitor, 20 (6-ethyl-5-[3-(3,4,5-trimethoxyphenyl)prop-1-yn-1-y...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	57.0	n/a	n/a	7	25
University of Connecticut					J Med Chem. 51: 7532-40 (2008)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	Pyrrolo[2, 3-d]pyrimidine analogue, 2 ((2S)-2-{[4-({2,4-diamino-5-ethyl-7H-pyrrolo[2,3-d]...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	n/a	n/a	66.0	n/a	68.0	7.4	30
Duquesne University					J Med Chem. 50: 3046-3053 (2007)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	Pyrrolo[3,2-d]pyrimidine analogue, 4 ((2S)-2-{[4-({2-amino-6-methyl-4-oxo-3H,4H,5H-pyrro...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	120.0	n/a	n/a	7.4	30
Duquesne University					J Med Chem. 51: 68-76 (2008)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	Propargyl inhibitor, 22 (5-[3-(2,3-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylp...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	130.0	n/a	n/a	7	25
University of Connecticut					J Med Chem. 51: 7532-40 (2008)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	Pyrrolo[2, 3-d]pyrimidine analogue, 1a ((2S)-2-{[4-({2,4-diamino-5-methyl-7H-pyrrolo[2,3-d...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	n/a	n/a	210.0	n/a	190.0	7.4	30
Duquesne University					J Med Chem. 50: 3046-3053 (2007)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	Pyrrolo[2, 3-d]pyrimidine analogue, 1a ((2S)-2-{[4-({2,4-diamino-5-methyl-7H-pyrrolo[2,3-d...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	n/a	n/a	210.0	n/a	190.0	7.4	30
Duquesne University					J Med Chem. 48: 7215-22 (2005)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	thieno[2,3-d]pyrimidine deriv., 2c	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	260.0	n/a	n/a	7.4	30
Duquesne University					J Med Chem. 52: 4892-902 (2009)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	thieno[2,3-d]pyrimidine deriv., 2j	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	260.0	n/a	n/a	7.4	30
Duquesne University					J Med Chem. 52: 4892-902 (2009)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	thieno[2,3-d]pyrimidine deriv., 2f	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	280.0	n/a	n/a	7.4	30
Duquesne University					J Med Chem. 52: 4892-902 (2009)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	thieno[2,3-d]pyrimidine deriv., 2e	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	290.0	n/a	n/a	7.4	30
Duquesne University					J Med Chem. 52: 4892-902 (2009)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	2,4-diaminopyrimidine derivative, 8a (6-[(benzyloxy)methyl]-5-(4-{[(4-chlorophenyl)methy...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	n/a	n/a	300.0	n/a	n/a	7.3	37
Abbott Laboratories					J Med Chem. 49: 2568-78 (2006)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	thieno[2,3-d]pyrimidine deriv., 2k	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	300.0	n/a	n/a	7.4	30
Duquesne University					J Med Chem. 52: 4892-902 (2009)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	thieno[2,3-d]pyrimidine deriv., 2b	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	300.0	n/a	n/a	7.4	30
Duquesne University					J Med Chem. 52: 4892-902 (2009)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	thieno[2,3-d]pyrimidine deriv., 2h	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	350.0	n/a	n/a	7.4	30
Duquesne University					J Med Chem. 52: 4892-902 (2009)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	Propargyl inhibitor, 24 (6-ethyl-5-(3-phenylprop-1-yn-1-yl)pyrimidine-2,4-d...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	360.0	n/a	n/a	7	25
University of Connecticut					J Med Chem. 51: 7532-40 (2008)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	TMP derivative with propargyl-based linker, 16 (6-methyl-5-[3-(3,4,5-trimethoxyphenyl)prop-1-yn-1-...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	n/a	n/a	400.0	n/a	n/a	7	25
University of Connecticut					J Med Chem. 51: 7532-40 (2008)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	Pyrrolo[2,3-d]pyrimidine analogue, 4 ((2S)-2-{[4-({2-amino-6-ethyl-4-oxo-3H,4H,7H-pyrrol...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	n/a	n/a	420.0	n/a	n/a	7.4	30
Duquesne University					J Med Chem. 49: 1055-65 (2006)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	thieno[2,3-d]pyrimidine deriv., 2l	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	540.0	n/a	n/a	7.4	30
Duquesne University					J Med Chem. 52: 4892-902 (2009)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	thieno[2,3-d]pyrimidine deriv., 2m	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	600.0	n/a	n/a	7.4	30
Duquesne University					J Med Chem. 52: 4892-902 (2009)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	thieno[2,3-d]pyrimidine deriv., 2i	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	620.0	n/a	n/a	7.4	30
Duquesne University					J Med Chem. 52: 4892-902 (2009)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	GW997 (5-(PHENYLSULFANYL)-2,4-QUINAZOLINEDIAMINE | 5-(ph...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	B.MOAD CSLS DrugBank MMDB PC cid PC sid PDB	PubMed	n/a	n/a	620.0	n/a	n/a	7	30
GSK					J Med Chem. 44: 2928-32 (2001)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	thieno[2,3-d]pyrimidine deriv., 2d	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	840.0	n/a	n/a	7.4	30
Duquesne University					J Med Chem. 52: 4892-902 (2009)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	GW578 (5-[(4-METHYLPHENYL)SULFANYL]-2,4-QUINAZOLINEDIAMIN...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	B.MOAD CHEBI CSLS DrugBank MMDB PC cid PC sid PDB	PubMed	n/a	n/a	940.0	n/a	n/a	7	30
GSK					J Med Chem. 44: 2928-32 (2001)
Dihydrofolate Reductase (DHFR) Homo sapiens (human)	TMP derivative with propargyl-based linker, 27 (5-[3-methoxy-3-(3,4,5-trimethoxyphenyl)prop-1-yn-1...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	n/a	n/a	1160.0	n/a	n/a	7	25
University of Connecticut					J Med Chem. 51: 7532-40 (2008)

Displayed 1 to 50 (of 132 total )  |  Next  |  Last  >>

Jump to:

• Reorder this table by ec50
• Reorder this table by ic50
• Reorder this table by kd
• Reorder this table by pH
• Reorder this table by T
• Change energy unit to:  kcal/mole