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Found 62 hits affinity hit(s) for enzyme = Dihydrofolate Reductase (DHFR) with UniProtKB: P16184
Target (Institution)	Ligand	Target Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	pH	Temp °C
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Piritrexim analogue, 10 (5-[3-({2,4-diamino-5-methylpyrido[2,3-d]pyrimidin-...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	0.097	n/a	n/a	7.4	37
Harvard Medical School			CSLS PubChem	PubMed	J Med Chem. 48: 4420-31 (2005)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Piritrexim analogue, 9 (4-[2-({2,4-diamino-5-methylpyrido[2,3-d]pyrimidin-...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	0.17	n/a	n/a	7.4	37
Harvard Medical School			CSLS PubChem	PubMed	J Med Chem. 48: 4420-31 (2005)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Piritrexim analogue, 6 (2,4-diamino-5-deazapteridine, 4 \| 4-[3-({2,4-diami...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	0.43	n/a	n/a	7.4	37
Harvard Medical School			CSLS PubChem	PubMed	J Med Chem. 48: 4420-31 (2005)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Piritrexim analogue, 7 (2,4-diamino-5-deazapteridine, 5 \| 5-[3-({2,4-diami...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	0.51	n/a	n/a	7.4	37
Harvard Medical School			CSLS PubChem	PubMed	J Med Chem. 48: 4420-31 (2005)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Piritrexim analogue, 13 (5-[2-({2,4-diamino-5-methylpyrido[2,3-d]pyrimidin-...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	0.65	n/a	n/a	7.4	37
Harvard Medical School			CSLS PubChem	PubMed	J Med Chem. 48: 4420-31 (2005)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Diaminopyrimidine analogue, 3 (6-{3-[(2,4-diaminopyrimidin-5-yl)methyl]-4,5-dimet...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PubChem	PubMed	n/a	n/a	1.0	n/a	n/a	7.4	37
Harvard Medical School			PubChem	PubMed	J Med Chem. 48: 4420-31 (2005)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Piritrexim analogue, 14 (6-[2-({2,4-diamino-5-methylpyrido[2,3-d]pyrimidin-...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	1.2	n/a	n/a	7.4	37
Harvard Medical School			CSLS PubChem	PubMed	J Med Chem. 48: 4420-31 (2005)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Piritrexim analogue, 8 (2,4-diamino-5-deazapteridine, 6 \| 6-[3-({2,4-diami...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	1.3	n/a	n/a	7.4	37
Harvard Medical School			CSLS PubChem	PubMed	J Med Chem. 48: 4420-31 (2005)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Piritrexim analogue, 11 (2,4-diamino-5-deazapteridine, 10 \| 6-[3-({2,4-diam...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	1.4	n/a	n/a	7.4	37
Harvard Medical School			CSLS PubChem	PubMed	J Med Chem. 48: 4420-31 (2005)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Piritrexim analogue, 12 (2,4-diamino-5-deazapteridine, 2 \| 7-[3-({2,4-diami...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	1.8	n/a	n/a	7.4	37
Harvard Medical School			CSLS PubChem	PubMed	J Med Chem. 48: 4420-31 (2005)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Piritrexim analogue, 56 (6-[(2-iodo-5-methoxyphenyl)methyl]-5-methylpyrido[...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	3.8	n/a	n/a	7.4	37
Harvard Medical School			CSLS PubChem	PubMed	J Med Chem. 48: 4420-31 (2005)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Piritrexim analogue, 55 (6-[(5-iodo-2-methoxyphenyl)methyl]-5-methylpyrido[...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	5.8	n/a	n/a	7.4	37
Harvard Medical School			CSLS PubChem	PubMed	J Med Chem. 48: 4420-31 (2005)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Piritrexim analogue,30 (2,4-diamino-5-deazapteridine, 7 \| ethyl 4-[3-({2,4...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	6.5	n/a	n/a	7.4	37
Harvard Medical School			CSLS PubChem	PubMed	J Med Chem. 48: 4420-31 (2005)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Pteridine analogue, 19 (4-{2-[(2,4-diaminopteridin-6-yl)methyl]-2-azatricy...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	9.4	n/a	n/a	7.4	37
Harvard Medical School			CSLS PubChem	PubMed	J Med Chem. 48: 4420-31 (2005)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Pteridine analogue, 21 (6-{2-[(2,4-diaminopteridin-6-yl)methyl]-2-azatricy...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	12.0	n/a	n/a	7.4	37
Harvard Medical School			CSLS PubChem	PubMed	J Med Chem. 48: 4420-31 (2005)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Piritrexim (6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	B.MOAD CSLS DrugBank PDB PubChem	PubMed	n/a	n/a	13.0	n/a	n/a	7.4	37
Harvard Medical School			B.MOAD CSLS DrugBank PDB PubChem	PubMed	J Med Chem. 48: 4420-31 (2005)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Piritrexim analogue,31 (2,4-diamino-5-deazapteridine, 8 \| ethyl 5-[3-({2,4...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	28.0	n/a	n/a	7.4	37
Harvard Medical School			CSLS PubChem	PubMed	J Med Chem. 48: 4420-31 (2005)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Piritrexim analogue,32 (2,4-diamino-5-deazapteridine, 9 \| ethyl 6-[3-({2,4...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	35.0	n/a	n/a	7.4	37
Harvard Medical School			CSLS PubChem	PubMed	J Med Chem. 48: 4420-31 (2005)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Trimetrexate (5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS DrugBank PDB PubChem	PubMed	n/a	n/a	42.0	n/a	n/a	7.4	37
Duquesne University			CSLS DrugBank PDB PubChem	PubMed	J Med Chem. 50: 3046-3053 (2007)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Diaminopyrimidine analogue, 22 (5-{2-bromo-5-[(2,4-diaminopyrimidin-5-yl)methyl]-3...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	71.0	n/a	n/a	7.4	37
Harvard Medical School			CSLS PubChem	PubMed	J Med Chem. 48: 4420-31 (2005)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Piritrexim analogue, 45 (ethyl 4-[2-({2,4-diamino-5-methylpyrido[2,3-d]pyri...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	83.0	n/a	n/a	7.4	37
Harvard Medical School			CSLS PubChem	PubMed	J Med Chem. 48: 4420-31 (2005)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Piritrexim analogue,38 (6-{[2-(benzyloxy)-5-methoxyphenyl]methyl}-5-methyl...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	96.0	n/a	n/a	7.4	37
Harvard Medical School			CSLS PubChem	PubMed	J Med Chem. 48: 4420-31 (2005)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Pteridine analogue, 20 (5-{2-[(2,4-diaminopteridin-6-yl)methyl]-2-azatricy...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	230.0	n/a	n/a	7.4	37
Harvard Medical School			CSLS PubChem	PubMed	J Med Chem. 48: 4420-31 (2005)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Iclaprim (5-[(2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl)me...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	2400.0	n/a	n/a	7	30
GSK			CSLS PubChem	PubMed	Bioorg Med Chem Lett. 13: 4217-21 (2003)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Pyrrolo[2, 3-d]pyrimidine analogue, 7 (6-[(3-chlorophenyl)sulfanyl]-5-ethyl-7H-pyrrolo[2,...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PubChem	PubMed	n/a	n/a	4020.0	n/a	n/a	7.4	37
Duquesne University			PubChem	PubMed	J Med Chem. 50: 3046-3053 (2007)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Pyrrolo[2, 3-d]pyrimidine analogue, 13 (6-[(2,5-dimethoxyphenyl)sulfanyl]-5-ethyl-7H-pyrro...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PubChem	PubMed	n/a	n/a	6040.0	n/a	n/a	7.4	37
Duquesne University			PubChem	PubMed	J Med Chem. 50: 3046-3053 (2007)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Pyrrolo[2, 3-d]pyrimidine analogue, 10 (6-[(2,4-dichlorophenyl)sulfanyl]-5-ethyl-7H-pyrrol...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PubChem	PubMed	n/a	n/a	7190.0	n/a	n/a	7.4	37
Duquesne University			PubChem	PubMed	J Med Chem. 50: 3046-3053 (2007)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Pyrrolo[2, 3-d]pyrimidine analogue, 5 (5-ethyl-6-[(4-nitrophenyl)sulfanyl]-7H-pyrrolo[2,3...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PubChem	PubMed	n/a	n/a	8680.0	n/a	n/a	7.4	37
Duquesne University			PubChem	PubMed	J Med Chem. 50: 3046-3053 (2007)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Pyrrolo[2, 3-d]pyrimidine analogue, 16 (5-ethyl-6-(quinolin-8-ylsulfanyl)-7H-pyrrolo[2,3-d...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PubChem	PubMed	n/a	n/a	9580.0	n/a	n/a	7.4	37
Duquesne University			PubChem	PubMed	J Med Chem. 50: 3046-3053 (2007)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Pyrrolo[2, 3-d]pyrimidine analogue, 8 (6-[(4-chlorophenyl)sulfanyl]-5-ethyl-7H-pyrrolo[2,...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PubChem	PubMed	n/a	n/a	11900.0	n/a	n/a	7.4	37
Duquesne University			PubChem	PubMed	J Med Chem. 50: 3046-3053 (2007)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Trimethoprim (5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	B.MOAD CSLS DrugBank PDB PubChem	B.MOAD PDB PubMed	n/a	n/a	12000.0	n/a	n/a	7.4	37
Duquesne University			B.MOAD CSLS DrugBank PDB PubChem	B.MOAD PDB PubMed	J Med Chem. 50: 3046-3053 (2007)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	2,4-diaminofuro[2,3-d]pyrimidine, 10	B.MOAD DrugBank GoogleScholar PDB UniProtKB/SwissProt	PubChem	PubMed	n/a	n/a	12500.0	n/a	n/a	7.4	37
Duquesne University	2,4-diaminofuro[2,3-d]pyrimidine, 10	B.MOAD DrugBank GoogleScholar PDB UniProtKB/SwissProt	PubChem	PubMed	Bioorg Med Chem. 17: 7324-36 (2009)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Trimethoprim (5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	B.MOAD CSLS DrugBank PDB PubChem	B.MOAD PDB PubMed	n/a	n/a	13000.0	n/a	n/a	7.4	37
Harvard Medical School			B.MOAD CSLS DrugBank PDB PubChem	B.MOAD PDB PubMed	J Med Chem. 48: 4420-31 (2005)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Pyrrolo[2, 3-d]pyrimidine analogue, 4 (5-ethyl-6-(naphthalen-2-ylsulfanyl)-7H-pyrrolo[2,3...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PubChem	PubMed	n/a	n/a	13880.0	n/a	n/a	7.4	37
Duquesne University			PubChem	PubMed	J Med Chem. 50: 3046-3053 (2007)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Pyrrolo[2, 3-d]pyrimidine analogue, 1i (6-[(2,5-dimethoxyphenyl)sulfanyl]-5-methyl-7H-pyrr...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	14600.0	n/a	n/a	7.4	37
Duquesne University			CSLS PubChem	PubMed	J Med Chem. 50: 3046-3053 (2007)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Pyrrolo[2, 3-d]pyrimidine analogue, 1d (6-[(4-chlorophenyl)sulfanyl]-5-methyl-7H-pyrrolo[2...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	16700.0	n/a	n/a	7.4	37
Duquesne University			CSLS PubChem	PubMed	J Med Chem. 50: 3046-3053 (2007)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Pyrrolo[2, 3-d]pyrimidine analogue, 3 (5-ethyl-6-(naphthalen-1-ylsulfanyl)-7H-pyrrolo[2,3...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PubChem	PubMed	n/a	n/a	18400.0	n/a	n/a	7.4	37
Duquesne University			PubChem	PubMed	J Med Chem. 50: 3046-3053 (2007)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Pyrrolo[2, 3-d]pyrimidine analogue, 1h (6-[(3,4-dichlorophenyl)sulfanyl]-5-methyl-7H-pyrro...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PubChem	PubMed	n/a	n/a	20000.0	n/a	n/a	7.4	37
Duquesne University			PubChem	PubMed	J Med Chem. 50: 3046-3053 (2007)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Pyrrolo[2, 3-d]pyrimidine analogue, 11 (6-[(2,6-dichlorophenyl)sulfanyl]-5-ethyl-7H-pyrrol...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PubChem	PubMed	n/a	n/a	20600.0	n/a	n/a	7.4	37
Duquesne University			PubChem	PubMed	J Med Chem. 50: 3046-3053 (2007)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Pyrrolo[2, 3-d]pyrimidine analogue, 9 (6-[(3,4-dichlorophenyl)sulfanyl]-5-ethyl-7H-pyrrol...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PubChem	PubMed	n/a	n/a	20700.0	n/a	n/a	7.4	37
Duquesne University			PubChem	PubMed	J Med Chem. 50: 3046-3053 (2007)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Pyrrolo[2, 3-d]pyrimidine analogue, 15 (5-ethyl-6-(phenylsulfanyl)-7H-pyrrolo[2,3-d]pyrimi...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PubChem	PubMed	n/a	n/a	21800.0	n/a	n/a	7.4	37
Duquesne University			PubChem	PubMed	J Med Chem. 50: 3046-3053 (2007)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	2,4-diaminofuro[2,3-d]pyrimidine, 4 (E/Z ratio=2:1)	B.MOAD DrugBank GoogleScholar PDB UniProtKB/SwissProt	PubChem	PubMed	n/a	n/a	22200.0	n/a	n/a	7.4	37
Duquesne University	2,4-diaminofuro[2,3-d]pyrimidine, 4 (E/Z ratio=2:1)	B.MOAD DrugBank GoogleScholar PDB UniProtKB/SwissProt	PubChem	PubMed	Bioorg Med Chem. 17: 7324-36 (2009)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	2,4-diaminofuro[2,3-d]pyrimidine, 5 (E/Z ratio=3:2)	B.MOAD DrugBank GoogleScholar PDB UniProtKB/SwissProt	PubChem	PubMed	n/a	n/a	25900.0	n/a	n/a	7.4	37
Duquesne University	2,4-diaminofuro[2,3-d]pyrimidine, 5 (E/Z ratio=3:2)	B.MOAD DrugBank GoogleScholar PDB UniProtKB/SwissProt	PubChem	PubMed	Bioorg Med Chem. 17: 7324-36 (2009)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Pyrrolo[2, 3-d]pyrimidine analogue, 6 (6-[(4-bromophenyl)sulfanyl]-5-ethyl-7H-pyrrolo[2,3...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PubChem	PubMed	n/a	n/a	26600.0	n/a	n/a	7.4	37
Duquesne University			PubChem	PubMed	J Med Chem. 50: 3046-3053 (2007)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Pyrrolo[2, 3-d]pyrimidine analogue, 14 (5-ethyl-6-[(3-methoxyphenyl)sulfanyl]-7H-pyrrolo[2...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PubChem	PubMed	n/a	n/a	28300.0	n/a	n/a	7.4	37
Duquesne University			PubChem	PubMed	J Med Chem. 50: 3046-3053 (2007)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	2,4-diaminofuro[2,3-d]pyrimidine, 1b (Z-isomer)	B.MOAD DrugBank GoogleScholar PDB UniProtKB/SwissProt	CSLS PubChem	PubMed	n/a	n/a	30000.0	n/a	n/a	7.4	37
Duquesne University	2,4-diaminofuro[2,3-d]pyrimidine, 1b (Z-isomer)	B.MOAD DrugBank GoogleScholar PDB UniProtKB/SwissProt	CSLS PubChem	PubMed	Bioorg Med Chem. 17: 7324-36 (2009)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	Pyrrolo[2, 3-d]pyrimidine analogue, 17 (6-[(2,6-dimethylphenyl)sulfanyl]-5-ethyl-7H-pyrrol...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PubChem	PubMed	n/a	n/a	30200.0	n/a	n/a	7.4	37
Duquesne University			PubChem	PubMed	J Med Chem. 50: 3046-3053 (2007)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	2,4-diaminofuro[2,3-d]pyrimidine, 11	B.MOAD DrugBank GoogleScholar PDB UniProtKB/SwissProt	PubChem	PubMed	n/a	n/a	30900.0	n/a	n/a	7.4	37
Duquesne University	2,4-diaminofuro[2,3-d]pyrimidine, 11	B.MOAD DrugBank GoogleScholar PDB UniProtKB/SwissProt	PubChem	PubMed	Bioorg Med Chem. 17: 7324-36 (2009)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	2,4-diaminofuro[2,3-d]pyrimidine, 3 (E/Z ratio=3:1)	B.MOAD DrugBank GoogleScholar PDB UniProtKB/SwissProt	PubChem	PubMed	n/a	n/a	34000.0	n/a	n/a	7.4	37
Duquesne University	2,4-diaminofuro[2,3-d]pyrimidine, 3 (E/Z ratio=3:1)	B.MOAD DrugBank GoogleScholar PDB UniProtKB/SwissProt	PubChem	PubMed	Bioorg Med Chem. 17: 7324-36 (2009)
Dihydrofolate Reductase (DHFR) Pneumocystis carinii	2,4-diaminofuro[2,3-d]pyrimidine, 2 (E/Z ratio=2:1)	B.MOAD DrugBank GoogleScholar PDB UniProtKB/SwissProt	PubChem	PubMed	n/a	n/a	37000.0	n/a	n/a	7.4	37
Duquesne University	2,4-diaminofuro[2,3-d]pyrimidine, 2 (E/Z ratio=2:1)	B.MOAD DrugBank GoogleScholar PDB UniProtKB/SwissProt	PubChem	PubMed	Bioorg Med Chem. 17: 7324-36 (2009)