Compile Data Set for Download or QSAR
(2D       Computed 3D by Vconf -m prep )

Data curated solely by BindingDB

Found 45 hits of affinity data for UniProtKB/TrEMBL: A5IS24

Target (Institution)	Ligand	Target Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	pH	Temp °C
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 64 (2-[2-({[(2R)-2-(4-bromothiophen-2-yl)-2-hydroxyeth...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	n/a	n/a	3.7	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 38 (2-[2-({[2-(4-bromothiophen-2-yl)-2-hydroxyethyl]am...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	n/a	n/a	8.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 43 (2-({[2-(benzyloxy)phenyl]methyl}amino)-1-(4-bromot...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	10.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 47 (1-(4-bromothiophen-2-yl)-2-({[2-(pyridin-4-ylmetho...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	16.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 46 (1-(4-bromothiophen-2-yl)-2-({[2-(pyridin-3-ylmetho...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	18.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 42 (1-(4-bromothiophen-2-yl)-2-({[2-(prop-2-en-1-yloxy...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	18.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 41 (1-(4-bromothiophen-2-yl)-2-[({2-[2-(morpholin-4-yl...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	18.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 59 (2-({[2-(4-aminobutoxy)phenyl]methyl}amino)-1-(4-br...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	22.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 55 (3-[2-({[2-(4-bromothiophen-2-yl)-2-hydroxyethyl]am...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	25.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 44 (1-(4-bromothiophen-2-yl)-2-[({2-[(4-methanesulfony...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	26.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 48 (2-({[2-(1H-1,3-benzodiazol-2-ylmethoxy)phenyl]meth...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	26.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 58 (4-[2-({[2-(4-bromothiophen-2-yl)-2-hydroxyethyl]am...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	26.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 57 (4-[2-({[2-(4-bromothiophen-2-yl)-2-hydroxyethyl]am...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	30.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 22 (2-({[2-(benzyloxy)phenyl]methyl}amino)-1-(3-chloro...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	31.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 23 (2-({[2-(benzyloxy)phenyl]methyl}amino)-1-(3-iodoph...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	32.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 50 (2-[2-({[2-(4-bromothiophen-2-yl)-2-hydroxyethyl]am...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	32.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 36 (1-(4-bromothiophen-2-yl)-2-({[2-(methoxymethoxy)ph...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	35.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 54 (3-[2-({[2-(4-bromothiophen-2-yl)-2-hydroxyethyl]am...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	36.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 49 (2-[2-({[2-(4-bromothiophen-2-yl)-2-hydroxyethyl]am...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	42.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 45 (1-(4-bromothiophen-2-yl)-2-({[2-(pyridin-2-ylmetho...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	43.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 56 (4-[2-({[2-(4-bromothiophen-2-yl)-2-hydroxyethyl]am...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	43.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 37 (2-[2-({[2-(4-bromothiophen-2-yl)-2-hydroxyethyl]am...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	49.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 13 (2-({[2-(benzyloxy)phenyl]methyl}amino)-1-[3-(trifl...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	50.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 34 (1-(4-bromothiophen-2-yl)-2-{[(2-methoxyphenyl)meth...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	50.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 53 (3-[2-({[2-(4-bromothiophen-2-yl)-2-hydroxyethyl]am...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	58.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 12 (2-({[2-(prop-2-en-1-yloxy)phenyl]methyl}amino)-1-[...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	58.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 60 (2-{4-[2-({[2-(4-bromothiophen-2-yl)-2-hydroxyethyl...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	69.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 24 (2-({[2-(benzyloxy)phenyl]methyl}amino)-1-(3-methox...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	83.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 9 (2-[({2-hydroxy-2-[3-(trifluoromethyl)phenyl]ethyl}...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	100.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 19 (2-{[(2-methoxyphenyl)methyl]amino}-1-(3-methylphen...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	110.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 52 (2-[2-({[2-(4-bromothiophen-2-yl)-2-hydroxyethyl]am...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	110.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 18 (1-(3-bromophenyl)-2-{[(2-methoxyphenyl)methyl]amin...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	110.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 51 (2-[2-({[2-(4-bromothiophen-2-yl)-2-hydroxyethyl]am...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	120.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 35 (1-(4-bromothiophen-2-yl)-2-{[(2-phenoxyphenyl)meth...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	120.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 1 (2-(benzylamino)-1-[3-(trifluoromethyl)phenyl]ethan...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	160.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 11 (2-{[(2-methoxyphenyl)methyl]amino}-1-[3-(trifluoro...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	160.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 20 (2-{[(2-methoxyphenyl)methyl]amino}-1-[3-(trifluoro...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	190.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 39 (2-({[2-(2-aminoethoxy)phenyl]methyl}amino)-1-(4-br...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	220.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 40 (2-{2-[2-({[2-(4-bromothiophen-2-yl)-2-hydroxyethyl...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	250.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 10 (2-({[2-(difluoromethoxy)phenyl]methyl}amino)-1-[3-...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	260.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 25 (2-({[2-(benzyloxy)phenyl]methyl}amino)-1-[3-(hydro...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	570.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 6 (2-{[(2-methylphenyl)methyl]amino}-1-[3-(trifluorom...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	790.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 65 (2-[2-({[(2S)-2-(4-bromothiophen-2-yl)-2-hydroxyeth...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	>1000.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 7 (2-[({2-hydroxy-2-[3-(trifluoromethyl)phenyl]ethyl}...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	2500.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)
tRNA synthetase (PheRS) Staphylococcus aureus	ethanolamine, 8 (2-({[2-(morpholin-4-yl)phenyl]methyl}amino)-1-[3-(...)	GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	10000.0	n/a	n/a	7.9	37
GSK					Bioorg Med Chem Lett. 15: 2305-9 (2005)

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• Change energy unit to:  kcal/mole