BindingDB PrimarySearch

Found 23 hits of kd for UniProtKB: P10275
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM50367916 (METHYLTRIENOLONE \| Metribolone \| R-1881) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	Purchase CHEBI DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	0.520	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant for [3H]R-1881 binding to human androgen receptor at 278 K				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Androgen Receptor (Homo sapiens (Human))	BDBM50367916 (METHYLTRIENOLONE \| Metribolone \| R-1881) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	Purchase CHEBI DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	0.560	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant for [3H]R-1881 binding to human androgen receptor at 283 K				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Androgen Receptor (Homo sapiens (Human))	BDBM50367916 (METHYLTRIENOLONE \| Metribolone \| R-1881) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	Purchase CHEBI DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a
University of Illinois Curated by ChEMBL					Assay Description Binding affinity to androgen receptor				J Med Chem 53: 3349-60 (2010) Article DOI: 10.1021/jm100052k BindingDB Entry DOI: 10.7270/Q2BP03RQ
University of Illinois Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Androgen Receptor (Homo sapiens (Human))	BDBM50367916 (METHYLTRIENOLONE \| Metribolone \| R-1881) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	Purchase CHEBI DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	0.610	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant for [3H]R-1881 binding to human androgen receptor at 273 K				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Androgen Receptor (Homo sapiens (Human))	BDBM50367916 (METHYLTRIENOLONE \| Metribolone \| R-1881) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	Purchase CHEBI DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	0.680	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant for [3H]R-1881 binding to human androgen receptor at 288 K				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Androgen Receptor (Homo sapiens (Human))	BDBM50367916 (METHYLTRIENOLONE \| Metribolone \| R-1881) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	Purchase CHEBI DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	0.740	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant value of the radiolabeled compound against the androgen receptor 293 K				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Androgen Receptor (Homo sapiens (Human))	BDBM50367916 (METHYLTRIENOLONE \| Metribolone \| R-1881) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	Purchase CHEBI DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	0.990	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant for [3H]R-1881 binding to human androgen receptor at 298 K				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Androgen Receptor (Homo sapiens (Human))	BDBM50367916 (METHYLTRIENOLONE \| Metribolone \| R-1881) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	Purchase CHEBI DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	1.21	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant for [3H]R-1881 binding to human androgen receptor at 303 K				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Androgen Receptor (Homo sapiens (Human))	BDBM50131272 (3-(4-Fluoro-phenyl)-4-[1-(4-pyrrolidin-1-yl-phenyl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Dissociation constant against GST-hARLBD was measured in SC-3 cell by using [3H]-testosterone as radioligand				Bioorg Med Chem Lett 13: 2655-8 (2003) Article DOI: 10.1016/s0960-894x(03)00575-4 BindingDB Entry DOI: 10.7270/Q26D5SDD
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen Receptor (Homo sapiens (Human))	BDBM50131269 (3-(2-Fluoro-phenyl)-4-[1-(4-pyrrolidin-1-yl-phenyl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Dissociation constant against GST-hARLBD was measured in SC-3 cell by using [3H]-testosterone as radioligand				Bioorg Med Chem Lett 13: 2655-8 (2003) Article DOI: 10.1016/s0960-894x(03)00575-4 BindingDB Entry DOI: 10.7270/Q26D5SDD
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen Receptor (Homo sapiens (Human))	BDBM50131271 (3-(4-Hydroxy-phenyl)-4-[1-(4-pyrrolidin-1-yl-pheny...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Dissociation constant against GST-hARLBD was measured in SC-3 cell by using [3H]-testosterone as radioligand				Bioorg Med Chem Lett 13: 2655-8 (2003) Article DOI: 10.1016/s0960-894x(03)00575-4 BindingDB Entry DOI: 10.7270/Q26D5SDD
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen Receptor (Homo sapiens (Human))	BDBM50131268 (4-[1-(4-Dibutylamino-phenyl)-meth-(Z)-ylidene]-3-p...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Dissociation constant against GST-hARLBD was measured in SC-3 cell by using [3H]-testosterone as radioligand				Bioorg Med Chem Lett 13: 2655-8 (2003) Article DOI: 10.1016/s0960-894x(03)00575-4 BindingDB Entry DOI: 10.7270/Q26D5SDD
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen Receptor (Homo sapiens (Human))	BDBM50367916 (METHYLTRIENOLONE \| Metribolone \| R-1881) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	Purchase CHEBI DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	1.51	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant for [3H]R-1881 binding to human androgen receptor at 308 K				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Androgen Receptor (Homo sapiens (Human))	BDBM50367916 (METHYLTRIENOLONE \| Metribolone \| R-1881) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	Purchase CHEBI DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	1.95	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant for [3H]R-1881 binding to human androgen receptor at 310K				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Androgen Receptor (Homo sapiens (Human))	BDBM334273 (2-Butyl-2- hydroxy-hexanoic acid (2-bromo- pyridin...) Show SMILES CCCCC(O)(CCCC)C(=O)Nc1ccnc(Br)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a
Galderma Research & Development US Patent					Assay Description The N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides described herein exhibit androgen receptor (AR) inhibiting properties. This AR inhibiting activ...				US Patent US9732044 (2017) BindingDB Entry DOI: 10.7270/Q2348NHJ
Galderma Research & Development US Patent					More data for this Ligand-Target Pair
Androgen Receptor (Homo sapiens (Human))	BDBM334276 (2-Hydroxy-2,4- dimethyl-pentanoic acid (2-bromo-6-...) Show SMILES COc1cc(NC(=O)C(C)(O)CC(C)C)cc(Br)n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a
Galderma Research & Development US Patent					Assay Description The N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides described herein exhibit androgen receptor (AR) inhibiting properties. This AR inhibiting activ...				US Patent US9732044 (2017) BindingDB Entry DOI: 10.7270/Q2348NHJ
Galderma Research & Development US Patent					More data for this Ligand-Target Pair
Androgen Receptor (Homo sapiens (Human))	BDBM334272 (2-Hydroxy-2- methyl-hexanoic acid (2-bromo- 6-meth...) Show SMILES CCCCC(C)(O)C(=O)Nc1cc(Br)nc(OC)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a
Galderma Research & Development US Patent					Assay Description The N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides described herein exhibit androgen receptor (AR) inhibiting properties. This AR inhibiting activ...				US Patent US9732044 (2017) BindingDB Entry DOI: 10.7270/Q2348NHJ
Galderma Research & Development US Patent					More data for this Ligand-Target Pair
Androgen Receptor (Homo sapiens (Human))	BDBM334271 (2-Hydroxy-2- methyl- pentanoic acid (2-bromo-pyrid...) Show SMILES CCCC(C)(O)C(=O)Nc1ccnc(Br)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a
Galderma Research & Development US Patent					Assay Description The N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides described herein exhibit androgen receptor (AR) inhibiting properties. This AR inhibiting activ...				US Patent US9732044 (2017) BindingDB Entry DOI: 10.7270/Q2348NHJ
Galderma Research & Development US Patent					More data for this Ligand-Target Pair
Androgen Receptor (Homo sapiens (Human))	BDBM334277 (N-(2-Bromo-pyridin- 4-yl)-2-hydroxy- 2-methyl-4-ph...) Show SMILES CC(O)(CCc1ccccc1)C(=O)Nc1ccnc(Br)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a
Galderma Research & Development US Patent					Assay Description The N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides described herein exhibit androgen receptor (AR) inhibiting properties. This AR inhibiting activ...				US Patent US9732044 (2017) BindingDB Entry DOI: 10.7270/Q2348NHJ
Galderma Research & Development US Patent					More data for this Ligand-Target Pair
Androgen Receptor (Homo sapiens (Human))	BDBM334275 (N-(2-Bromo- pyridin-4-yl)-2- hydroxy-2-phenyl- pro...) Show SMILES CC(O)(C(=O)Nc1ccnc(Br)c1)c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a
Galderma Research & Development US Patent					Assay Description The N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides described herein exhibit androgen receptor (AR) inhibiting properties. This AR inhibiting activ...				US Patent US9732044 (2017) BindingDB Entry DOI: 10.7270/Q2348NHJ
Galderma Research & Development US Patent					More data for this Ligand-Target Pair
Androgen Receptor (Homo sapiens (Human))	BDBM334274 (N-(2-Bromo-pyridin- 4-yl)-2-hydroxy-4- (4-methoxy-...) Show SMILES COc1ccc(CCC(C)(O)C(=O)Nc2ccnc(Br)c2)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
Galderma Research & Development US Patent					Assay Description The N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides described herein exhibit androgen receptor (AR) inhibiting properties. This AR inhibiting activ...				US Patent US9732044 (2017) BindingDB Entry DOI: 10.7270/Q2348NHJ
Galderma Research & Development US Patent					More data for this Ligand-Target Pair
Androgen receptor/Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human))	BDBM50529667 (CHEMBL4444904 \| US10806720, Compound 11) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	Purchase PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of androgen receptor AF1 domain (141 to 486 residues) (unknown origin) incubated for 30 mins by steady-state fluorescence emission spectro...				J Med Chem 63: 11330-11361 (2020)
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen Receptor (Homo sapiens (Human))	BDBM334278 (4-(2-Hydroxy-2- methyl- pentanoylamino)- pyridine-...) Show SMILES CCCC(C)(O)C(=O)Nc1ccnc(c1)C(=O)OC Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a
Galderma Research & Development US Patent					Assay Description The N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides described herein exhibit androgen receptor (AR) inhibiting properties. This AR inhibiting activ...				US Patent US9732044 (2017) BindingDB Entry DOI: 10.7270/Q2348NHJ
Galderma Research & Development US Patent					More data for this Ligand-Target Pair